Sinemet - a combined remedy based on Levodopum + Carbidopum. In the treatment of Parkinson's syndrome and disease, Sinemet proved to be one of the most effective drug. The reviews are mostly positive, because it allows to reduce "inhibition" in patients who have been treated with other medications. For each patient, the dosage is selected individually, together with the frequency of admission.
Sinemet
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| 500mg × 30 Pills | $1.73 | $51.84 + Bonus - 4 Pills | - | Add to cart |
| 500mg × 60 Pills | $1.41 | $84.71 + Bonus - 4 Pills | $19.20 | Add to cart |
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| 500mg × 360 Pills | $1.22 | $440.33 + Bonus - 11 Pills Free Trackable Delivery | $183.60 | Add to cart |
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| 300mg × 30 Pills | $1.72 | $51.71 + Bonus - 4 Pills | - | Add to cart |
| 300mg × 60 Pills | $1.45 | $87.06 + Bonus - 4 Pills | $16.20 | Add to cart |
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| 300mg × 360 Pills | $1.22 | $440.57 + Bonus - 11 Pills Free Trackable Delivery | $180.00 | Add to cart |
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| 250mg × 30 Pills | $1.45 | $43.46 + Bonus - 4 Pills | - | Add to cart |
| 250mg × 60 Pills | $1.19 | $71.44 + Bonus - 4 Pills | $15.60 | Add to cart |
| 250mg × 90 Pills | $1.05 | $94.53 + Bonus - 7 Pills | $36.00 | Add to cart |
| 250mg × 120 Pills | $0.94 | $112.76 + Bonus - 7 Pills | $61.20 | Add to cart |
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| 110mg × 30 Pills | $0.88 | $26.46 + Bonus - 4 Pills | - | Add to cart |
| 110mg × 60 Pills | $0.72 | $43.39 + Bonus - 4 Pills | $9.60 | Add to cart |
| 110mg × 90 Pills | $0.67 | $60.33 + Bonus - 7 Pills | $18.90 | Add to cart |
| 110mg × 120 Pills | $0.64 | $77.27 + Bonus - 7 Pills | $28.80 | Add to cart |
| 110mg × 180 Pills | $0.62 | $111.13 + Bonus - 11 Pills | $46.80 | Add to cart |
| 110mg × 270 Pills | $0.60 | $161.94 + Bonus - 11 Pills | $75.60 | Add to cart |
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Sinemet Product Description
Drug Uses
Sinemet is a combination drug related to a therapeutic class known as antiparkinsonian agents. Sinemet is used to manage rare and more common forms of parkinsonism or parkinsonian syndrome, such as:
Parkinson's disease (PD)
Symptomatic and post-encephalitic parkinsonism
Sinemet stops or reduces progression of parkinsonism symptoms, including symptoms that can result in disability. This effect is achieved because Sinemet improves the process of replenishing dopamine in the brain.
At the beginning of the parkinsonian syndrome treatment, one tablet of Sinemet 25/ 100mg should be taken, three times a day. The dosage can be increased by one tablet every 24 or 48 hours till the maximum recommended daily Sinemet dosage of eight 25/100mg tablets is achieved.
Missed dose
If you’ve missed the assigned dosage of Sinemet, take the antiparkinsonian agent as soon as you remember. However, do not take Sinemet if it is time for the next prescribed dosage of this drug. Return to regular dosing schedule of Sinemet on the next day.
More Information
Combined dopaminergic drug Sinemet starts acting within first days of treatment, and sometimes even after the first dose intake. The clinically significant antiparkinsonian effect is achieved within 7-10 days after initiating Sinemet-therapy.
Storage
Antiparkinsonian agent Sinemet should be protected from strong light and excessive moisture under 30°C, and kept in an original package thoroughly sealed.
Sinemet Safety Information
Warnings
Sinemet should not be used if movement disorders, changes in behavior, hyperkinesia, and other extrapyramidal reactions were caused by drugs. In rare cases, the use of combined dopaminergic drug Sinemet may cause severe drowsiness, even in the middle of the day. Usually involuntary sleep episodes appear at the beginning of the parkinsonism treatment.
Disclaimer
Information about treatment of Parkinson's disease, provided in this review of Sinemet, is offered only “as-is” for informational and educational purposes only. This information is not implied to be a substitute for professional medical advice of the neurologist, neurosurgeon or other medical professional. The online pharmacy shall not be liable for any injury, which may be caused by improper use of the information on antiparkinsonian agent Sinemet.
Sinemet Side Effects
Most adverse reactions of Sinemet are mild and normally disappear after the daily dosage of the antiparkinsonian agent is decreased. The most often Sinemet may cause in the patients with parkinsonism such reactions as dyskinesia, chest pain, low blood pressure, vomiting, gastrointestinal bleeding, nausea, angioedema, shortness of breath, flushing, loss of hair, back pain or shoulder pain.
In rare cases, the patients taking Sinemet complain of: asthenia, anorexia, diarrhea, dark saliva, palpitation, muscle cramps, low platelet count, urticaria, pruritus, dizziness, somnolence, urinary tract infection or swelling.
An anthelmintic broad-spectrum drug; most effective with enterobioze and trihozefaleze. Causes irreversible violation of glucose utilization, depletes the glycogen stores in the tissues of worms, inhibits the synthesis of cellular tubulin and also inhibits the ATP synthesis.
In case of an arterial hypertension of Atacand causes dose-dependent long lowering of arterial pressure. Anti-hypertensive action happens due to decrease in system peripheric resistance without reflex increase in heart rate. Instructions on serious or strengthened hypotension after taking of the first dose or Withdrawal Effect after termination of treatment are absent.
The antibiotic produced by Streptomyces lincolniensis, has a bacteriostatic effect. Suppresses protein synthesis of bacteria due to reversible binding to the 50S subunit of ribosomes, disrupts the formation of peptide bonds.
It is active against gram-positive cocci Streptococcus spp., including Streptococcus pneumoniae); Haemophilus influenzae; Bacillus anthracis, Mycoplasma spp., Bacteroides spp., Corynebacterium diphtheriae, Clostridium perfringens, Clostridium tetani.
Being a part of the medicine Allegra - fexofenadine it is an antihistamine with a selective antagonistic activity to H1-receptors without anticholinergic and blocking alfa1-adrenergic receptors; also at fexofenadine isn't observed a sedative action and other effects from the central nervous system. The antihistaminic effect of Allegra is observed in 1 hour, reaching its maximum in 6 hours, and proceeds within 24 hours. After 28 days of taking the medicine there wasn't observed the accustoming to it.
The medicine is blue or white tablets, the dose of the active substance is 75, 100 and 150 mg. Tablets have the bitter taste and a slight anesthetic effect on the oral mucosa. Pills may be quickly dissolved in water. Bupron is a second-generation antidepressant. Its effectiveness as an anti-nicotine drug is based on the suppression of psychological dependence on nicotine (nicotine dependence), as well as on the direct antidepressant effect, which reduces the negative manifestations that appear when a person gives up smoking.
Antidepressant. Strengthens the central adrenergic and serotonergic transfer. Used for the treatment of depressions including anhedonia, psychomotor retardation, insomnia, early awakening, weight loss, loss of interest in life, suicidal thoughts and mood swings.
Januvia - is a drug for adult patients with type 2 diabetes mellitus, in order to control the glycemic level under conditions of monotherapy as part of combined treatment regimens. The drug is prescribed to patients with ineffectiveness of diet therapy in combination with optimal physical activity, with the impossible use of metformin because of its intolerance.
An antifungal agent from the group of imidazole derivatives for external and local applications reduces the synthesis of ergosterol, which is a part of the cell membrane of the microbial wall and leads to a change in its structure and properties. In fungicidal concentrations, it interacts with mitochondrial and peroxidase enzymes, leading to an increase in the concentration of hydrogen peroxide to toxic levels, which also contributes to the destruction of fungal cells. The pills are active against pathogenic dermatophytes, pathogens of multi-colored lichen, erythrasma, gram-positive and gram-negative bacteria.
Tinidazole - an antibacterial agent for systemic intake, used for the treatment of diseases such as trichomoniasis, giardiasis, amoeba dysentery, anaerobic infection, mixed aerobic-anaerobic infections (in combination with appropriate antibiotics), prevention of postoperative anaerobic infections.
Teramycin acts depressingly on pathogens of many diseases, as well as biomycin. It is less toxic and longer preserves its action in the body. The medicine is used for the treatment of anthrax, teileriosis, cholera and pasteurellosis and other diseases.
Lisinopril is an antihypertensive, vasodilating, cardioprotective drug, an ACE inhibitor that is used to treat hypertension, heart failure, acute myocardial infarction, diabetic nephropathy.
Tricor - is a hypolipidemic agent, has an uricosuric and antiplatelet effect. In combination with diet therapy, the drug is prescribed for a long-term treatment, the effectiveness of which must be periodically checked by determining serum lipid levels.
A lipid-lowering agent. Reversibly inhibits HMG-COA reductase, inhibits the cholesterol synthesis at the stage of mevinolinic acid and moderately reduces its intracellular concentration. The indications for the drug use include: primary hypercholesterolemia mainly of IIa and IIb types, under the ineffective diet treatment in patients with increased risk of coronary atherosclerosis, hypercholesterolemia combined with hypertriglyceridemia; prevention of coronary artery disease. The drug decreases the risk of myocardial infarction, the need for revascularization of the myocardium, deaths from cardiovascular system diseases.
Caduet consists of Amlodipine besylate and atorvastatin calcium. Caduet has a double mechanism of action; action of amlodipin as dihydropyridinic antagonist of calcium and for suppression of atorvastatin HMG-CoA reductase. It is taken for prevention of cardiovascular events at patients with hypertension, with three concurrent factors of cardiovascular risk, with cholesterol level from normal to moderately raised, without clinical manifestations of ischemic heart disease and also when according to the existing recommendations about treatment the combined use of amlodipin and low dose of atorvastatin is deemed appropriate.
Viagra Plus is the latest form of the medical treatment which is known worldwide. The formula is intensified by active medicinal plants, causing a boundless feeling of potentiality, unlimited desire and infinite lasting. The ginseng is one of the main ingredients of Viagra Plus, which carries out stimulation and increases endocrine activity in an organism, strengthens metabolism and facilitates cordial activity, helping thereby an arterial flow of blood, stimulating think-tanks and is promoted also by simplification of functioning of the central nervous system. Erection, sexual desire, success of sexual intercourse are guaranteed. From 400 mg of Viagra Plus - 50 mg make sildenafit, the remained 350 mg are ginseng and vitamins.
Zudena is another representative of the PDE5 inhibitors ubiquitously used in contemporary urology. It is commonly used for the therapy and prevention of erectile dysfunction. The pills contain udenafil – a reverse inhibitor of the phosphodiesterase-5, which is responsible for filling the penis with blood. This active ingredient has a range of recently introduced advantages the most notable of which are more rapid absorption (30-60 minutes) and increased half-life (starting from 10 to 12 hours, which leads to a 24-hour period of activity). The medicine may be prescribed not only for symptomatic but also for a long-term treatment.
Tadacip - an Indian brand, whose main chemical element is tadalafil, which is also a principal part of Cialis pills. It's been created by Cipla Ltd. with a more lucrative cost in comparison to Cialis made by the brand-maker Eli Lilly.
Florinef is a brand name of Fludrocortisone. It is a corticosteroid produced to treat adrenogenital syndrome (also called Apera-Galle syndrome), Addison's disease, orthostatic hypotension, cerebral salt wasting syndrome, and adrenal insufficiency. The drug replenishes the deficiency of hormones of the adrenal cortex. 1 tablet contains 0.1 mg of fludrocortisone acetate. It participates in the metabolism, including mineral and carbohydrate one. The drug causes the retention of sodium ions and promotes the excretion of potassium.
stimulant of the intestinal peristalsis. Motillium is assigned in cases of: distention, overeating, vomiting, heartburn, flatulence, a feeling of overflow of the stomach.
An antimicrobial bactericide - synthetic derivative of nitroimidazole. Used in urethritis, vaginitis, intestinal amoebiasis, liver amoebiasis, giardiasis.
Depakote - antiepileptic medicine, has the central myorelaxation and sedative effect. It is taken for treatment of epilepsy of various genesis, at epileptic seizures, febrile spasms at children, and character changes caused by epilepsy.
The drug has a thymoleptic and anxiolytic effect. Prescribed for the treatment of depressions of various origins, enuresis including the night one.
Cytoxan antineoplastic medicine of alkylating action, it has also immunodepressive effect. It is taken for treatment of small-celled lung cancer, ovarian cancer, cancer of a neck and uterus, cancer of bladder, prostate cancer, blastoma and leucosis.
Vastarel - the main substance of the drug is trimetazidine, which is used for the prevention of angina attacks in IHD, as well as in vertigo caused by violations of cerebral circulation, Meniere's disease, noise in the ears. It is believed that the beneficial effect of trimetazidine in myocardial ischemia is mainly associated with its antioxidant and antihypoxic properties and cytoprotective effects on the function of cardiomyocytes.
An antispasmodic drug, which removes pain and reduces the tone of smooth muscles: gastrointestinal tract, biliary tract, uterus, it also relaxes the detrusor (direct antispasmodic and m-anticholinergic effect). Increases bladder capacity, reduces the frequency of detrusor contractions, hinders urination. Well tolerated when appointed for a long term. Used in neurogenic bladder (including detrusor hyperreflexia, multiple sclerosis or spina bifida), urinary incontinence (of idiopathic origin), nocturnal enuresis (in children older than 5 years).
The local application of Rogaine 2 has a stimulating effect on hair growth in men and women with androgenetic alopecia. In clinical studies, it is reported that Regain stimulates hair growth and stops it falling out in cases when it begins to fall from the top (men) or in the middle part (women). The stimulation of hair growth begins approximately 4 months after using the product. After the withdrawal of the drug, the growth of new hair stops. In patients with normal or high blood pressure, a local use of the medicine was not accompanied by common side effects.
Combined oral contraceptives block the action of gonadotropins. The first effect of these drugs is aimed to inhibit ovulation. The drug leads to modifications in cervical mucus. Thus, it is strenuous for sperm to pass to the uterine cavity and affect the uterine lining, thereby reducing the possibility of implementation. It helps to prevent pregnancy. Moreover, oral contraceptives prevent pregnancy and have a number of advantages. They have an impact on the cycle of menses and it becomes regular. The amount of blood loss at the time of menstruation is shorter as well as the loss of iron, dysmenorrhea is rare.
Atorlip-10 belongs to the drugs which reduce the level of low-density lipoprotein and triglycerides. Doctors identify the level with the help of blood tests. If the level is rather high, then the patients are prescribed the pills. Heart attack, strokes, high blood pressure, diabetes, and other cardiovascular diseases can be prevented thanks to the medicine. The pills are effective in case the disease is acquired due to the improper way of living or when it’s inherited.
Gasex arranges the work of the intestine and reduces the time of digestion process. The drug acts as spasmolytic, antiulcerant, anti-inflammatory agent, cholagogue, hepatoprotective agent, membrane-modulating agent, an antimicrobial agent, and antioxidant. The drug also improves the digestibility of vitamins. It’s used for symptomatic control and relief of dyspepsia (upset stomach). The drug is used in case of flatulence, bloating, belching and for preliminary radiographic preparation of the intestine for radiography. The pills cope with discomfort in the abdomen in the postoperative period or during prolonged immobilization.
Diabecon is aimed at increasing peripheral glucose intake, restoring B cells, increasing C – peptide levels. Diabecon has antioxidant properties, protecting cells from oxidative stress. The drug eliminates the painful symptoms of diabetes: polyuria, fever, burning feet and hands. Symptoms are eliminated not immediately after administration but within two to three weeks. This is due to changes in chemical processes in the body that cause symptoms of the disease. Diabecon naturally reduces craving for sweets, restores the patient's appetite, normalizes the functions of liver and kidney.
Super P-Force is produced by the outstanding Indian company in the world of the pharma mart, named Sunrise Remedies. Now, one will escape from the issues with the penile function and forget about unanticipated ejaculation. It's worth ordering Super P Force even when such a product is not prescribed to you, but you just plan to raise the quality of a lovemaking procedure to a higher level.
Hytrin refers to the group of pharmaceutical products intended to cure the sexual/urinary maladies and sex hormone medical preparations. Its composition includes Terazozin - a medical mean for the normalization of the prostate gland in benign hypertrophy.
Trileptal is used to treat simple and complex forms of partial epileptic seizures that have secondary generalization (possibly without it) beginning at the age of one month; generalized tonic-clonic forms of epileptic seizures in patients from two years of age. Reviews about Trileptal have a positive connotation, which allows to determine its effectiveness in use, thanks to patients who have experience of taking the drug.
The medicine is a cardioselective blocker of beta-1-adrenergic receptors. A major risk index for glaucomatous scotoma is an increased tension. When its rate is soaring, the eyes are more damaged. As a consequence, a visual field narrows. Betoptic reduces both increased and usual pressure, regardless of if it occurs with glaucoma, or not; the structure of its activity is connected with a decline in the performance of intraocular fluid. Betaxolol acts after half-an-hour, and the expected result is normally achieved after 2 hours after application.
Coumadin is a drug that promotes blood thinning in the veins. Within a short period of application, anticoagulant reduces viscous blood consistency and lowers the risk of blood clots. The drug is prescribed only after laboratory blood tests when certain symptoms are detected. Independent use of tablets is prohibited, only a doctor may establish the need for taking the drug. Thrombosis is a disease that is characterized by the formation of blood clots. In case of delayed treatment, this disease may cause disorders of oxygen metabolism in the blood and embolism.
Anticholinesterase agent; having a cholinesterase effect through a reversible acetylcholinesterase inhibition and enhancing the action of acetylcholine. Improves neuromuscular transmission, increases the motility of the gastrointestinal tract, increases the tone of urinary bladder, bronchi, the secretion of exocrine glands. Prescribed for myasthenia gravis, postoperative intestinal atony, atonic constipation, bladder atony, post-traumatic movement disorders; flaccid paralysis; residual explication of polio, encephalitis, violation of emptying the bladder after gynecological surgery and childbirth.
Deltasone - renders an antiinflammatory, antiallergic, antishock and immunodepressive effect. It is taken for treatment of acute and chronic inflammatory diseases of joints, acute asthma, allergic diseases, skin diseases.
Xenical - a powerful, specific and reversible inhibitor of gastrointestinal lipases, which has a long-lasting effect. Its therapeutic effect is carried out in the lumen of the stomach and small intestine and consists in the formation of a covalent bond with the active serine portion of the gastric and pancreatic lipases. The inactivated enzyme at the same time loses the ability to break down food fats coming in the form of triglycerides, to sucking free fatty acids and monoglycerides. Since uncleaved triglycerides are not absorbed, the resulting decrease in the intake of calories into the body leads to a decrease in body weight. Thus, the therapeutic effect of the drug is carried out without absorption into the systemic circulation.
Xeloda is a cytostatic drug. The drug is used for the treatment of patients with metastatic or locally advanced breast cancer, including after an ineffective chemotherapy course, which included anthracycline drugs and taxanes, and also if the patient has contraindications to anthracyclines.
A nonsteroidal anti-inflammatory drug that has anti-inflammatory, analgesic, antipyretic action. Prescribed for inflammatory diseases of the musculoskeletal system (rheumatoid, gouty arthritis, arthritis, ankylosing spondylitis), pain syndrome (ossalgia, neuralgia, myalgia, arthralgia, sciatica, headache, dental pain, childbirth), for orthopedic surgery, cancer, algodismenorrhea, febrile syndrome.
Fosamax - drug for treatment of Paget disease, osteoporosis at women in a postmenopause, osteoporosis at men, a hypercalcemia at malignant tumors. Active alendronate ingredient - non-hormonal specific inhibitor of an osteoclastic bone resorption, suppresses osteoclasts. Taking of Fosamax stimulates bone formation, recovers positive balance between a resorption and recovery of a bone, progressively increases the mineral density of bones, promotes formation of a normal bone tissue with normal histologic structure.