Etodolac - has an anti-inflammatory, analgesic, antipyretic effect. The medicine is prescribed in case of rheumatoid arthritis, ankylosing spondylitis, arthrosis with pain syndrome and restriction of movements, acute and chronic osteoarthritis.
Etodolac
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Etodolac product description
Etodolac is a non-steroidal anti-inflammatory medication manufactured in tablets. The main purpose of the tablets is analgesic and antipyretic. This is an indoleacetic acid derivative that is distinguished by the presence of a tetrahydropyranol nucleus. This substance has an anti-inflammatory, analgesic, antipyretic effect. The drug reduces the production of prostaglandins from arachidonic acid by blocking the enzyme cyclooxygenase. This mechanism provides a decrease in the receptor sensitivity to mediators of pain (bradykinin, histamine), a decrease in exudation, migration of leukocytes, and sensitivity of thermoregulatory centers to the action of endogenous pyrogens. Etodolac has a moderate specificity with respect to COX-2, due to which it acts mainly in the centers of inflammation. The use of Etodolac is very popular due to its active influences on the three elements of the inflammatory process: pain, temperature and the cause of inflammation. This medical preparation is used for emergency or prolonged therapy of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis. It is also consumed to eliminate pain syndrome of any etiology.
Etodolac safety information
As with other non-steroidal anti-inflammatory preparations, it is advisable to take Etodolac after meals or with food, or antacid agents to reduce irritation of the gastrointestinal mucosa, especially with prolonged admission. There are known cases of hypersensitivity reactions to NVS or acetylsalicylic acid, anesthesia after aortocoronary shunting, special sensitivity to any of the elements of the composition, an ulcer active or recurrent, in the active phase, severe liver, kidney or heart failure.
The medication is also not used for the treatment of minors breastfeeding or pregnant.
The combination with other NSAIDs increases the risk of abdominal bleeding and peptic ulcer of the stomach. Etodolac enhances the results of the oral anticoagulants based on coumarin or indanedione derivatives. Increases the concentration of lithium in the blood plasma and increases the hematological toxicity of methotrexate.
Cefamandole, cefoperazone, cefotetan, valproic acid can lead to hypoprothrombinemia, and plicamycin or valproic acid can suppress platelet aggregation. The medical remedy is able to enhance the hypoglycemic effect of sulfonamides.
Among the other contraindications - peptic ulcer of the stomach, duodenum; bronchial asthma, rhinitis, hives in anamnesis, which occurred after taking acetylsalicylic acid or other NSAIDs; a severe allergic reaction in the anamnesis, for example, an anaphylactic reaction or angioedema.
Etodolac side effects
Side reactions, such as of many medications of this group, are present in this medication, among them there is nausea, vomiting (possibly with blood), fastening or upset of the stool, ulceration of the walls of the stomach, intestines, ulcerative stomatitis, weakness, dizziness, allergies on the skin and others, they are clearly marked with instructions. The reduction of the likelihood of their occurrence can be achieved by the correction of the dosage for an intake.
An anthelmintic broad-spectrum drug; most effective with enterobioze and trihozefaleze. Causes irreversible violation of glucose utilization, depletes the glycogen stores in the tissues of worms, inhibits the synthesis of cellular tubulin and also inhibits the ATP synthesis.
The antibiotic produced by Streptomyces lincolniensis, has a bacteriostatic effect. Suppresses protein synthesis of bacteria due to reversible binding to the 50S subunit of ribosomes, disrupts the formation of peptide bonds.
It is active against gram-positive cocci Streptococcus spp., including Streptococcus pneumoniae); Haemophilus influenzae; Bacillus anthracis, Mycoplasma spp., Bacteroides spp., Corynebacterium diphtheriae, Clostridium perfringens, Clostridium tetani.
Being a part of the medicine Allegra - fexofenadine it is an antihistamine with a selective antagonistic activity to H1-receptors without anticholinergic and blocking alfa1-adrenergic receptors; also at fexofenadine isn't observed a sedative action and other effects from the central nervous system. The antihistaminic effect of Allegra is observed in 1 hour, reaching its maximum in 6 hours, and proceeds within 24 hours. After 28 days of taking the medicine there wasn't observed the accustoming to it.
The medicine is blue or white tablets, the dose of the active substance is 75, 100 and 150 mg. Tablets have the bitter taste and a slight anesthetic effect on the oral mucosa. Pills may be quickly dissolved in water. Bupron is a second-generation antidepressant. Its effectiveness as an anti-nicotine drug is based on the suppression of psychological dependence on nicotine (nicotine dependence), as well as on the direct antidepressant effect, which reduces the negative manifestations that appear when a person gives up smoking.
Antidepressant. Strengthens the central adrenergic and serotonergic transfer. Used for the treatment of depressions including anhedonia, psychomotor retardation, insomnia, early awakening, weight loss, loss of interest in life, suicidal thoughts and mood swings.
Januvia - is a drug for adult patients with type 2 diabetes mellitus, in order to control the glycemic level under conditions of monotherapy as part of combined treatment regimens. The drug is prescribed to patients with ineffectiveness of diet therapy in combination with optimal physical activity, with the impossible use of metformin because of its intolerance.
Tinidazole - an antibacterial agent for systemic intake, used for the treatment of diseases such as trichomoniasis, giardiasis, amoeba dysentery, anaerobic infection, mixed aerobic-anaerobic infections (in combination with appropriate antibiotics), prevention of postoperative anaerobic infections.
Lisinopril is an antihypertensive, vasodilating, cardioprotective drug, an ACE inhibitor that is used to treat hypertension, heart failure, acute myocardial infarction, diabetic nephropathy.
Tricor - is a hypolipidemic agent, has an uricosuric and antiplatelet effect. In combination with diet therapy, the drug is prescribed for a long-term treatment, the effectiveness of which must be periodically checked by determining serum lipid levels.
A lipid-lowering agent. Reversibly inhibits HMG-COA reductase, inhibits the cholesterol synthesis at the stage of mevinolinic acid and moderately reduces its intracellular concentration. The indications for the drug use include: primary hypercholesterolemia mainly of IIa and IIb types, under the ineffective diet treatment in patients with increased risk of coronary atherosclerosis, hypercholesterolemia combined with hypertriglyceridemia; prevention of coronary artery disease. The drug decreases the risk of myocardial infarction, the need for revascularization of the myocardium, deaths from cardiovascular system diseases.
Caduet consists of Amlodipine besylate and atorvastatin calcium. Caduet has a double mechanism of action; action of amlodipin as dihydropyridinic antagonist of calcium and for suppression of atorvastatin HMG-CoA reductase. It is taken for prevention of cardiovascular events at patients with hypertension, with three concurrent factors of cardiovascular risk, with cholesterol level from normal to moderately raised, without clinical manifestations of ischemic heart disease and also when according to the existing recommendations about treatment the combined use of amlodipin and low dose of atorvastatin is deemed appropriate.
Zudena is another representative of the PDE5 inhibitors ubiquitously used in contemporary urology. It is commonly used for the therapy and prevention of erectile dysfunction. The pills contain udenafil – a reverse inhibitor of the phosphodiesterase-5, which is responsible for filling the penis with blood. This active ingredient has a range of recently introduced advantages the most notable of which are more rapid absorption (30-60 minutes) and increased half-life (starting from 10 to 12 hours, which leads to a 24-hour period of activity). The medicine may be prescribed not only for symptomatic but also for a long-term treatment.
Tadacip - an Indian brand, whose main chemical element is tadalafil, which is also a principal part of Cialis pills. It's been created by Cipla Ltd. with a more lucrative cost in comparison to Cialis made by the brand-maker Eli Lilly.
stimulant of the intestinal peristalsis. Motillium is assigned in cases of: distention, overeating, vomiting, heartburn, flatulence, a feeling of overflow of the stomach.
An antimicrobial bactericide - synthetic derivative of nitroimidazole. Used in urethritis, vaginitis, intestinal amoebiasis, liver amoebiasis, giardiasis.
Depakote - antiepileptic medicine, has the central myorelaxation and sedative effect. It is taken for treatment of epilepsy of various genesis, at epileptic seizures, febrile spasms at children, and character changes caused by epilepsy.
The drug has a thymoleptic and anxiolytic effect. Prescribed for the treatment of depressions of various origins, enuresis including the night one.
Cytoxan antineoplastic medicine of alkylating action, it has also immunodepressive effect. It is taken for treatment of small-celled lung cancer, ovarian cancer, cancer of a neck and uterus, cancer of bladder, prostate cancer, blastoma and leucosis.
The local application of Rogaine 2 has a stimulating effect on hair growth in men and women with androgenetic alopecia. In clinical studies, it is reported that Regain stimulates hair growth and stops it falling out in cases when it begins to fall from the top (men) or in the middle part (women). The stimulation of hair growth begins approximately 4 months after using the product. After the withdrawal of the drug, the growth of new hair stops. In patients with normal or high blood pressure, a local use of the medicine was not accompanied by common side effects.
Combined oral contraceptives block the action of gonadotropins. The first effect of these drugs is aimed to inhibit ovulation. The drug leads to modifications in cervical mucus. Thus, it is strenuous for sperm to pass to the uterine cavity and affect the uterine lining, thereby reducing the possibility of implementation. It helps to prevent pregnancy. Moreover, oral contraceptives prevent pregnancy and have a number of advantages. They have an impact on the cycle of menses and it becomes regular. The amount of blood loss at the time of menstruation is shorter as well as the loss of iron, dysmenorrhea is rare.
Atorlip-10 belongs to the drugs which reduce the level of low-density lipoprotein and triglycerides. Doctors identify the level with the help of blood tests. If the level is rather high, then the patients are prescribed the pills. Heart attack, strokes, high blood pressure, diabetes, and other cardiovascular diseases can be prevented thanks to the medicine. The pills are effective in case the disease is acquired due to the improper way of living or when it’s inherited.
Diabecon is aimed at increasing peripheral glucose intake, restoring B cells, increasing C – peptide levels. Diabecon has antioxidant properties, protecting cells from oxidative stress. The drug eliminates the painful symptoms of diabetes: polyuria, fever, burning feet and hands. Symptoms are eliminated not immediately after administration but within two to three weeks. This is due to changes in chemical processes in the body that cause symptoms of the disease. Diabecon naturally reduces craving for sweets, restores the patient's appetite, normalizes the functions of liver and kidney.
Trileptal is used to treat simple and complex forms of partial epileptic seizures that have secondary generalization (possibly without it) beginning at the age of one month; generalized tonic-clonic forms of epileptic seizures in patients from two years of age. Reviews about Trileptal have a positive connotation, which allows to determine its effectiveness in use, thanks to patients who have experience of taking the drug.
The medicine is a cardioselective blocker of beta-1-adrenergic receptors. A major risk index for glaucomatous scotoma is an increased tension. When its rate is soaring, the eyes are more damaged. As a consequence, a visual field narrows. Betoptic reduces both increased and usual pressure, regardless of if it occurs with glaucoma, or not; the structure of its activity is connected with a decline in the performance of intraocular fluid. Betaxolol acts after half-an-hour, and the expected result is normally achieved after 2 hours after application.
Coumadin is a drug that promotes blood thinning in the veins. Within a short period of application, anticoagulant reduces viscous blood consistency and lowers the risk of blood clots. The drug is prescribed only after laboratory blood tests when certain symptoms are detected. Independent use of tablets is prohibited, only a doctor may establish the need for taking the drug. Thrombosis is a disease that is characterized by the formation of blood clots. In case of delayed treatment, this disease may cause disorders of oxygen metabolism in the blood and embolism.
Anticholinesterase agent; having a cholinesterase effect through a reversible acetylcholinesterase inhibition and enhancing the action of acetylcholine. Improves neuromuscular transmission, increases the motility of the gastrointestinal tract, increases the tone of urinary bladder, bronchi, the secretion of exocrine glands. Prescribed for myasthenia gravis, postoperative intestinal atony, atonic constipation, bladder atony, post-traumatic movement disorders; flaccid paralysis; residual explication of polio, encephalitis, violation of emptying the bladder after gynecological surgery and childbirth.
Xeloda is a cytostatic drug. The drug is used for the treatment of patients with metastatic or locally advanced breast cancer, including after an ineffective chemotherapy course, which included anthracycline drugs and taxanes, and also if the patient has contraindications to anthracyclines.
A nonsteroidal anti-inflammatory drug that has anti-inflammatory, analgesic, antipyretic action. Prescribed for inflammatory diseases of the musculoskeletal system (rheumatoid, gouty arthritis, arthritis, ankylosing spondylitis), pain syndrome (ossalgia, neuralgia, myalgia, arthralgia, sciatica, headache, dental pain, childbirth), for orthopedic surgery, cancer, algodismenorrhea, febrile syndrome.
Fosamax - drug for treatment of Paget disease, osteoporosis at women in a postmenopause, osteoporosis at men, a hypercalcemia at malignant tumors. Active alendronate ingredient - non-hormonal specific inhibitor of an osteoclastic bone resorption, suppresses osteoclasts. Taking of Fosamax stimulates bone formation, recovers positive balance between a resorption and recovery of a bone, progressively increases the mineral density of bones, promotes formation of a normal bone tissue with normal histologic structure.