Antiepileptic agent; binds to the additional subunit (a2-delta protein) of the potential-dependent Ca2 + -channels in the CNS, which promotes the manifestation of analgesic and anticonvulsant action. Reduction in the frequency of seizures begins within the first week.
Lyrica
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| 150mg × 30 Pills | $1.37 | $41.06 + Bonus - 4 Pills | - | Add to cart |
| 150mg × 60 Pills | $1.09 | $65.59 + Bonus - 4 Pills | $16.80 | Add to cart |
| 150mg × 90 Pills | $1.07 | $96.74 + Bonus - 7 Pills | $27.00 | Add to cart |
| 150mg × 120 Pills | $1.06 | $126.77 + Bonus - 7 Pills | $37.20 | Add to cart |
| 150mg × 240 Pills | $0.98 | $235.85 + Bonus - 11 Pills Free Trackable Delivery | $93.60 | Add to cart |
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| 75mg × 30 Pills | $0.95 | $28.46 + Bonus - 4 Pills | - | Add to cart |
| 75mg × 60 Pills | $0.77 | $45.99 + Bonus - 4 Pills | $10.80 | Add to cart |
| 75mg × 90 Pills | $0.74 | $66.64 + Bonus - 7 Pills | $18.90 | Add to cart |
| 75mg × 120 Pills | $0.70 | $84.07 + Bonus - 7 Pills | $30.00 | Add to cart |
| 75mg × 240 Pills | $0.65 | $155.35 + Bonus - 11 Pills | $72.00 | Add to cart |
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Lyrica product description
An active ingredient of Lyrica is pregabalin, which has an anticonvulsant and antiepileptic effect. Corporation Pfizer synthesized pregabalin at the end of the last century. The company initially positioned Lyrica as a modern antiepileptic agent, devoid of serious side effects typical for this class of drugs, and not causing addiction. Later it turned out that Lyrica remarkably fights anxiety and relieves depression, and the area of application has naturally expanded. The mechanism of action of Lyrica has not been completely studied yet. It is known that the substance acts on the same areas of the brain as tranquilizers, but it is not clear why it causes the physical and mental excitement not peculiar to tranquilizers. In medical circles pregabalin has established itself as a drug for the treatment of epilepsy and anxiety disorders.
Lyrica safety information
During Lyrica treatment, it is necessary to evade from driving vehicles and practicing potentially dangerous activities that require a high concentration of attention and speed of psychomotor reactions.
Women of reproductive age should use reliable methods of contraception, while treatment of Lyrica. The drug is prescribed to pregnant women only if the intended benefit to the mother outweighs the risk to the fetus.
If patients with diabetes mellitus on the background of taking Lyrica increased body weight, correction of doses of hypoglycemic medicines is necessary. Treatment of the elderly can cause dizziness and drowsiness, which increases the risk of injury in the latter.
Do not administer Lyrica to patients with hypersensitivity to pregabalinum or other components of the drug. The drug is contraindicated for children under 17, women during lactation and people with impaired lactose absorption and intolerance to lactose.
Interaction with other substances
Pregabalin is metabolized to an insignificant degree in the body and practically does not bind to plasma proteins, so the pharmacokinetic interaction of Lyric with other drugs is unlikely.
The intake of Lyrica can enhance the effects of Lorazepam and ethanol. With the simultaneous use of pregabalin and oxycodone, there is an increase in impairments of the mnestic function and the basic motor functions, which are caused by the intake of oxycodone.
The drug does not affect the pharmacological effects of other anticonvulsants, as well as the effectiveness of oral contraceptives, diuretics, oral antidiabetics, and insulin.
Lyrica side effects
In evidence-based medicine, there is no evidence of the negative effect of Lyrica on the liver. The fact is that pregabalin is not processed in the liver, therefore its toxic effect on this organ is minimal. Regarding the influence of Lyrica on sexual function - there is no reliable information about the irreversible damage to the testicles and impotence caused by Lyrica. But the negative impact of Lyrica on the kidneys does not cause any doubt. Many patients complain of swollen limbs and pain in the lumbar region during treatment with pregabalin. In addition, according to a recent experiment in mice, pregabalin and its predecessors can interfere with the development of cellular bonds in the brain, which is fraught with early dementia.
Allopurinol - a drug that promotes the excretion of uric acid and the removal of urinary calculi.
Zyloprim is a tablet the effect of which appears due to the mechanism of action of its basic component called Allopurinol. This medicine is prescribed as a treatment of hyperuricemia, primary and secondary gout, urolithiasis with the formation of urinary calculi, hemoblastoma, cytostatic and radiation therapy of tumors, psoriasis, traumatic toxicosis. It is used as a corticosteroid therapy for the prevention of urinary acid nephropathy, malignant neoplasms and congenital disorders of purine metabolism in children.
Sinequan - antidepressant, which is taken as prescribed by the doctor in case of the following indications: depression, anxiety and sleep disturbance in neuroses, alcoholism, organic diseases of the central nervous system, psychoneurotic disorders with anxiety, depression, psychotic depression (including the involutionary, reactive depressive phase of manic-depressive Psychosis). In general therapeutic practice - duodenal ulcer, dumping syndrome, premenstrual syndrome, chronic pain in cancer patients, skin itching, chronic idiopathic urticaria.
An antituberculosis drug which acts bacteriostatically; it enters the actively growing cells of mycobacteria by inhibiting RNA synthesis, interferes with cellular metabolism, causing cessation of reproduction and death of bacteria. Active only in relation to the intensively dividing cells. Inhibits the growth and reproduction of tuberculosis mycobacterium resistant to streptomycin, isoniazid, PASK, ethionamide, kanamycin. In the conditions of monotherapy, the resistance of mycobacteria develops fast enough.
Tetracycline has a wide range of antibacterial activity. It interferes with the formation of a complex between the transport RNA and the ribosome, which leads to a violation of protein synthesis by a microbial cell. Active in relation to most gram-positive and gram-negative bacteria, spiophets, leptospires, rickettsiaes, trachomae pathogens, ornithosis, and large viruses.
Dipyridamole medicine for treatment and prevention of thrombosis and thromboembolism, prevention of occlusion of stents and aortocoronary shunts. Expands coronary vessels (preferential arterioles) and causes significant increase in volume speed of a blood velocity. Increases the level of oxygen in a venous blood of a coronary sine and its absorption by a myocardium.
The medicine is used for the temporary correction of male erectile disorders. It represents the last generation of drugs for men, as it was developed less than 10 years ago and has the most modern composition than the previous tablets for treating of potency.Avanafil is an active substance of the drug.In the process of excitation in the cavernous body of the male sexual organ,, it relaxes the arteries and vessels to increase blood flow in the right places. The enzyme FDE-5 in some cases disrupts the natural process, not allowing accumulating cGMP to the required level.
Viagra Super Active - an innovative formula of drug for treatment of erectile dysfunction. Drug is produced in gelatin capsules that allows to avoid emergence of heartburn or other unpleasant feelings in a stomach. Sildenafil Super Active also has a number of advantages. It is soaked quicker and works longer. The principle of action is identical with ordinary Sildenafil. Each capsule contains about 100 mg of active ingredient. That is quite enough for any man.
Cialis Professional - effective tablets for improvement of erection. They begin to work in 15 minutes from the moment of taking and actions for 36 hours. They can cause not less than 10, but no more than 16 erections. The medicine increases duration of sexual intercourse. The tablets are successfully used for reduction of time for recovery of erection after ejaculation.
Cialis Super Active is a generic drug, against erectile dysfunction, containing 20 mg of tadalafil. The tablets in this series have a gel inside. This form allows the active substance, Tadalafil, to immediately enter the blood, thus providing an immediate effect. The result from the Cialis Super Active tablets appears after 5 minutes! The action lasts for two days. The drug is safe and has virtually no contraindications.
Apcalis SX - Tadalafil pills, released by Ajanta in 20mg dosage. Being equal to Cialis by an outcome and the way of an action, this innovative medical mean is also directed at enhancing the hardness of the male sexual organ and reducing the period on the restoration of the male potency after the sexual act.
Methocarbamol – a muscle relaxant used to treat muscle spasms and pain. Its action is to block pain nerve impulses sent to the brain. The mechanism of action is not completely clear. The drug has no direct effect on skeletal muscles. It's likely that its effect is associated with sedative properties.
The drug Malegra (Malegra DXT) contains two active substances in one pill: Sildenafil citrate 100 mg (as in a conventional tablet of Viagra) and Duloxetine, belonging to selective serotonin and norepinephrine reuptake inhibitors. The latter was invented by Eli Lilly and has long been used to prevent premature ejaculation. This is the latest drug that helps to treat erectile dysfunction. This medicine does not have an adverse effect on the cardiovascular system. The biggest advantage of this drug is its safety. Duloxetine gives the maximum effect together with Sildenafil citrate.
Celebrex - non-steroidal anti-inflammatory drug. It has antiinflammatory, febrifugal and analgesic effect, slows down aggregation of thrombocytes. Oppressing COX-2, reduces quantity of Pg (preferentialy in the inflammation center), suppresses exudative and proliferative phases of inflammation. At prescribtion in high doses, prolonged use or specific features of an organism the selectivity decreases.
It is a combined drug with a fixed solution of dosages of active substances -lisinopril and amlodipine. The first one is a blocker of the enzyme peptidyl. The second hormone activates the discharge of aldosterone by the cortex. ACE restriction leads to reduced absorption of angiotensin.
Since the mechanism is based on the inhibition of the aldosterone and chemosin systems. The pill reduces an arterial pressure in people with high tension as well.