Cozaar is used to treat arterial hypertension, protect the kidneys in type 2 diabetes mellitus with proteinuria, reduce the risk of associated cardiovascular diseases, as well as lower the death rate for hypertension, hypertrophy.
Cozaar
| Package | pill | Total price | Save | Order |
|---|---|---|---|---|
| 50mg × 28 Pills | $1.07 | $29.99 + Bonus - 4 Pills | - | Add to cart |
| 50mg × 56 Pills | $0.86 | $47.98 + Bonus - 4 Pills | $11.76 | Add to cart |
| 50mg × 112 Pills | $0.75 | $83.97 + Bonus - 7 Pills | $35.84 | Add to cart |
| 50mg × 224 Pills | $0.70 | $155.94 + Bonus - 11 Pills | $82.88 | Add to cart |
| Package | pill | Total price | Save | Order |
|---|---|---|---|---|
| 25mg × 30 Pills | $0.92 | $27.49 + Bonus - 4 Pills | - | Add to cart |
| 25mg × 60 Pills | $0.74 | $44.18 + Bonus - 4 Pills | $10.80 | Add to cart |
| 25mg × 90 Pills | $0.68 | $60.88 + Bonus - 7 Pills | $21.60 | Add to cart |
| 25mg × 120 Pills | $0.65 | $77.57 + Bonus - 7 Pills | $32.40 | Add to cart |
| 25mg × 180 Pills | $0.62 | $110.96 + Bonus - 11 Pills | $54.00 | Add to cart |
| 25mg × 270 Pills | $0.60 | $161.04 + Bonus - 11 Pills | $86.40 | Add to cart |
| 25mg × 360 Pills | $0.59 | $211.11 + Bonus - 11 Pills Free Trackable Delivery | $118.80 | Add to cart |
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Product Description
Cozaar (losartan) is a specific antagonist of angiotensin II receptors (subtype AT 1).Cozaar would not inhibit the kinase II enzyme, which catalyzes conversion reaction of angiotensin I to angiotensin II.
Cozaar decreases systemic vascular resistance (SVR), concentration of adrenalin and aldosterone in blood, hypertension, pressure of the pulmonary circuit; reduces afterload, provides urinative effect. Medication prevents myocardial hypertrophy, increases exercise tolerance in patients with cardiac decompensation (heart failure).
Safety information
Indications:
- Arterial hypertension.
- Congestive heart failure (in a combination therapy, in case of intolerance or ineffectiveness of angiotensin-converting-enzyme inhibitors (ACE inhibitors) therapy).
- Prevention of cardiovascular diseases (including stroke) and mortality in patients with arterial hypertension and left ventricular hypertrophy.
- Treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria (urinary albumin to creatinine ratio 300 mg/g or greater) in patients with type 2 diabetes and a history of hypertension (it slows the progression of diabetic nephropathy to terminal chronic renal failure).
- Hypersensitivity to the components of the drug.
- Pregnancy
- Lactation
- Use in people under 18 years old (no data about effectiveness and safety )
How to use Cozaar
The drug is taken orally. You may take Cozaar with or without food. The medicine should be taken once a day. Average daily intake for patients with arterial hypertension is 50 mg. In some cases, in order to achieve better therapeutic effect, the dose should be increased to 100mg and is taken per day or in 2 divided doses.
Initial dose for patients with heart failure is 12,5 mg once a day. Typically, the dose is increased with a weekly interval (ie 12,5 mg per day, 25 mg per day, 50 mg per day) to average maintenance dose 50 mg per day depending on patient’s tolerance of the drug.
Side effects
Most commonly, there are no side effects for losartan. If any discovered, they have transient character, so in general, there is no need to cancel the treatment. Rarely, the following symptoms may arise: drowsiness, anxiety, memory disorders, depression, paresthesia, tremor, hypoaesthesia, migraine, hearing disorders, visual impairments, taste blindness, bronchitis, dyspnea, rhinitis, stomachache, nausea, diarrhea, backache, pain in limbs and chest; cramps, myalgia, persistent hypotension, tachycardia or bradycardia, stenocardia, arrhythmia, anemia.
Bactrim - a combined drug, containing two active ingredients: sulfanamide drug sulfamethoxazole and derivative of diaminopyrimidine - trimethoprimum. Colibacillus life activity oppresses that leads to reduction of synthesis of thymine, riboflavinum, niacin, etc. group B vitamins in intestines. Duration of therapeutic effect makes 7 years.
An antiaggregant, used for the prevention of thrombotic complications in patients with acute coronary syndrome (ACS), who are planned to undergo percutaneous coronary angioplasty and for prevention of stent thrombosis in acute coronary syndromes. The medicine is a receptor antagonist of P2Y12class to adenosine diphosphate (ADP), and consequently inhibits the activation and aggregation of platelets. Since platelets are involved in the development of atherosclerosis complications, the inhibition of platelet function may lead to a decrease in the frequency of cardiovascular complications.
Aricept, which is donepezil - is prescribed at dementia which occured due to Alzheimer disease (mild and moderate severity) at adults, including elderly people (symptomatic treatment). Medicine works through inhibition in acetylcholinesterase of brain.
Zanaflex - muscle relaxant with the basic component tizanidine hydrochloride.
It is used to help loosen some muscles of your body. It relieves muscle spasms, which are the consequences of multiple sclerosis or spinal injuries.
Prednisone - is a drug from the group of hormones of the adrenal cortex (glucocorticosteroids). It contains prednisolone as the main substance. It is prescribed to patients who suffer from: Bechterew's disease, inflammatory changes in the spinal cord and membranes, non-infectious arthritis, edematous processes of the vertebrae and its structures, osteoarthrosis, severe soreness in the spine, spinal and nerve injuries of the spine, osteochondrosis.
Prometrium is used as part of hormone replacement therapy for women who underwent menopause (menopause) and did not have a hysterectomy (surgical removal of the uterus). Prometrium is also used to cause menstruation for women of childbearing age.