Cozaar is used to treat arterial hypertension, protect the kidneys in type 2 diabetes mellitus with proteinuria, reduce the risk of associated cardiovascular diseases, as well as lower the death rate for hypertension, hypertrophy.
Cozaar
| Package | pill | Total price | Save | Order |
|---|---|---|---|---|
| 50mg × 28 Pills | $1.07 | $29.99 + Bonus - 4 Pills | - | Add to cart |
| 50mg × 56 Pills | $0.86 | $47.98 + Bonus - 4 Pills | $11.76 | Add to cart |
| 50mg × 112 Pills | $0.75 | $83.97 + Bonus - 7 Pills | $35.84 | Add to cart |
| 50mg × 224 Pills | $0.70 | $155.94 + Bonus - 11 Pills | $82.88 | Add to cart |
| Package | pill | Total price | Save | Order |
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| 25mg × 30 Pills | $0.92 | $27.49 + Bonus - 4 Pills | - | Add to cart |
| 25mg × 60 Pills | $0.74 | $44.18 + Bonus - 4 Pills | $10.80 | Add to cart |
| 25mg × 90 Pills | $0.68 | $60.88 + Bonus - 7 Pills | $21.60 | Add to cart |
| 25mg × 120 Pills | $0.65 | $77.57 + Bonus - 7 Pills | $32.40 | Add to cart |
| 25mg × 180 Pills | $0.62 | $110.96 + Bonus - 11 Pills | $54.00 | Add to cart |
| 25mg × 270 Pills | $0.60 | $161.04 + Bonus - 11 Pills | $86.40 | Add to cart |
| 25mg × 360 Pills | $0.59 | $211.11 + Bonus - 11 Pills Free Trackable Delivery | $118.80 | Add to cart |
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Product Description
Cozaar (losartan) is a specific antagonist of angiotensin II receptors (subtype AT 1).Cozaar would not inhibit the kinase II enzyme, which catalyzes conversion reaction of angiotensin I to angiotensin II.
Cozaar decreases systemic vascular resistance (SVR), concentration of adrenalin and aldosterone in blood, hypertension, pressure of the pulmonary circuit; reduces afterload, provides urinative effect. Medication prevents myocardial hypertrophy, increases exercise tolerance in patients with cardiac decompensation (heart failure).
Safety information
Indications:
- Arterial hypertension.
- Congestive heart failure (in a combination therapy, in case of intolerance or ineffectiveness of angiotensin-converting-enzyme inhibitors (ACE inhibitors) therapy).
- Prevention of cardiovascular diseases (including stroke) and mortality in patients with arterial hypertension and left ventricular hypertrophy.
- Treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria (urinary albumin to creatinine ratio 300 mg/g or greater) in patients with type 2 diabetes and a history of hypertension (it slows the progression of diabetic nephropathy to terminal chronic renal failure).
- Hypersensitivity to the components of the drug.
- Pregnancy
- Lactation
- Use in people under 18 years old (no data about effectiveness and safety )
How to use Cozaar
The drug is taken orally. You may take Cozaar with or without food. The medicine should be taken once a day. Average daily intake for patients with arterial hypertension is 50 mg. In some cases, in order to achieve better therapeutic effect, the dose should be increased to 100mg and is taken per day or in 2 divided doses.
Initial dose for patients with heart failure is 12,5 mg once a day. Typically, the dose is increased with a weekly interval (ie 12,5 mg per day, 25 mg per day, 50 mg per day) to average maintenance dose 50 mg per day depending on patient’s tolerance of the drug.
Side effects
Most commonly, there are no side effects for losartan. If any discovered, they have transient character, so in general, there is no need to cancel the treatment. Rarely, the following symptoms may arise: drowsiness, anxiety, memory disorders, depression, paresthesia, tremor, hypoaesthesia, migraine, hearing disorders, visual impairments, taste blindness, bronchitis, dyspnea, rhinitis, stomachache, nausea, diarrhea, backache, pain in limbs and chest; cramps, myalgia, persistent hypotension, tachycardia or bradycardia, stenocardia, arrhythmia, anemia.
Pamelor is a tricyclic antidepressant (TCA, tricyclic antidepressants) of the second generation. It is used in the treatment of some major depressive disorder and nocturnal enuresis (bedwetting) in children. In addition, the drug is sometimes used for the treatment of chronic diseases such as chronic fatigue syndrome, chronic pain and migraine, and the lability in certain neurological diseases.
Benicar is a drug that is prescribed for essential arterial hypertension. In case of arterial hypertension, olmesartan causes a dose-dependent long-term reduction of a blood pressure.
A receptors blocker angiotensin II (AT1 type). Has a vasodilating and hypotensive effect. Does not show the properties of the agonist of angiotensin receptors, does not affect the state of ionic channels involved in the regulation of SSS. Does not inhibit ACE. Decreases both systolic and diastolic blood pressure without affecting the pulse rate. The start of antihypertensive action is in 3 hours, a steady decrease of the blood pressure is in 4 weeks after the start of the treatment. The duration of the hypotensive effect after a single intake is 24 hours.
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Prometrium is used as part of hormone replacement therapy for women who underwent menopause (menopause) and did not have a hysterectomy (surgical removal of the uterus). Prometrium is also used to cause menstruation for women of childbearing age.