Dulcolax - purgative. Causes irritation of the receptor of bowels, exerts direct impact at mucous membrane of intestines, strengthening its peristaltics and increasing secretion of slime in a large intestine. It is effective at hypotonic and colonic inertia for regulation of fecal matter. Sometimes it is taken at preparation for surgeries, instrumental examinationand and radiological researches.
Dulcolax
| Package | pill | Total price | Save | Order |
|---|---|---|---|---|
| 5mg × 60 Pills | $0.39 | $23.44 + Bonus - 4 Pills | - | Add to cart |
| 5mg × 90 Pills | $0.32 | $28.48 + Bonus - 7 Pills | $6.30 | Add to cart |
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Product Description
Dulcolax (bisacodil) is a prodrug. When ingested in an alkaline environment, hydrolysis takes place forming a substance that exerts an irritant effect on the gastrointestinal mucosa (the secretion of mucus in the large intestine increases, its peristalsis accelerates and intensifies). When ingested, it starts acting in 6-10 hours, being taken before the bedtime the drug starts acting in 8-12 hours.
Safety information
Indications:
- acute constipation;
- atony of the intestine after prolonged bed rest, changes in diet or the environment;
- hypotension and flaccid peristalsis of the colon (for example, in elderly patients);
- evacuation of the intestine before the examinations (X-ray, endoscopic), before and after operations, with severe cardiovascular diseases, during childbirth;
Mode of application
The drug may be indicated per os (through the mouth) and per rectum (in the rectum). Adults - 1-3 dragees per night or 1-2 suppositories (suppositories) rectally (in the rectum). If necessary, take an additional 1-3 tablets in the morning 30 minutes before taking breakfast. Usual single dose for adults is 5-10 mg (1 - 2 tablets). Doses for children are set according to their exact age.
Contraindications:
Intestinal obstruction,
strangulated hernia,
acute inflammatory diseases of the abdominal cavity (appendicitis, diverticulitis),
lack of potassium,
peritonitis,
bleeding from the gastrointestinal tract,
uterine bleeding,
cystitis,
spastic constipation,
acute proctitis,
acute hemorrhoids,
hypersensitivity to bisacodil.
Side effects
The most commonly reported adverse reactions during the use of the drug are spastic abdominal pain and diarrhea.
On the part of the digestive system: spasmodic pains or discomfort in the abdomen, diarrhea (dehydration, muscle weakness, convulsions, lowering blood pressure), nausea, vomiting, minor amounts of blood in the stool, anorectal discomfort, colitis.
On the part of the nervous system: dizziness, fainting.
These side effects arising from the usage of the drug are associated with vasovagal reaction (i.e., due to intestinal spasm, straining during defecation).
On the part of the immune system: hypersensitivity, angio-edema, anaphylactic reactions.
Claritin prevents development and facilitates the course of allergic reactions. Possesses antiallergic, antipruritic, antiexudative action. Reduces permeability of capillaries, controls oedemata of tissues, removes spasms of smooth muscles. It is prescribed at allergic rhinitis, conjunctivitis, pollinosis, urticaria fever, angioedema, pruritic dermatosis; pseudo-allergic reactions, caused by release of histamine; allergic reactions at stings of insects.
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Aristocort - glucocorticoid drug (the adrenal hormone influencing carbohydrate and protein metabolism). Renders prominent antiinflammatory, antiallergic and immunodepressive (suppressing immunity - body defences of an organism) effect. It is prescribed at rheumatism, allergic reactions, multiform erythema (variously proceeding skin disease which occurs with rubefaction of affected area of skin), pseudorheumatism (the infectious and allergic disease from a group of collagenoses which is characterized by chronic progressing inflammation of joints); systemic lupus erythematosus and other collagenoses.
The drug is an inhibitor of the enzyme peptidyl. It inhibits the angiotensin-converting enzyme, which catalyzes the conversion of angiotensin I to vasoconstrictor peptide angiotensin II. Angiotensin II also stimulates the secretion of aldosterone by the adrenal cortex. Inhibition of ACE leads to reduced concentrations of angiotensin II, resulting in low aldosterone secretion. The decrease in the latter leads to an increase in the content of potassium in the blood serum. Since the mechanism is believed to be based on the inhibition of the renin-angiotensin-aldosterone system, it reduces blood pressure even in patients with hypertension with low renin levels.
Naltrexone - complex treatment of alcohol dependence. It is also attributed to the prevention of the pharmacological effects of exogenous opioids and the maintenance of a non-opioid state in patients with opioid dependence.
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