The anti-malarial drug from the group of 8-aminohinolina derivatives. It is characterized by intercalation with DNA plasmodia, leading to disruption of nucleic acids synthesis. It demonstrates high activity against exo-erythrocytic forms of all types of malaria, including primary tissue and para- erythrocyte forms. Particularly active against primary tissue forms of Plasmodium falciparum.
Primaquine
| Package | pill | Total price | Save | Order |
|---|---|---|---|---|
| 15mg × 30 Pills | $1.82 | $54.66 + Bonus - 4 Pills | - | Add to cart |
| 15mg × 60 Pills | $1.38 | $82.64 + Bonus - 4 Pills | $26.40 | Add to cart |
| 15mg × 90 Pills | $1.22 | $109.93 + Bonus - 7 Pills | $54.00 | Add to cart |
| 15mg × 120 Pills | $1.07 | $128.15 + Bonus - 7 Pills | $90.00 | Add to cart |
| 15mg × 180 Pills | $1.00 | $179.26 + Bonus - 11 Pills | $147.60 | Add to cart |
| Package | pill | Total price | Save | Order |
|---|---|---|---|---|
| 7.5mg × 30 Pills | $1.54 | $46.15 + Bonus - 4 Pills | - | Add to cart |
| 7.5mg × 60 Pills | $1.37 | $81.93 + Bonus - 4 Pills | $10.20 | Add to cart |
| 7.5mg × 120 Pills | $1.28 | $153.48 + Bonus - 7 Pills | $31.20 | Add to cart |
| 7.5mg × 240 Pills | $1.24 | $296.59 + Bonus - 11 Pills Free Trackable Delivery | $72.00 | Add to cart |
| 7.5mg × 300 Pills | $1.23 | $368.15 + Bonus - 11 Pills Free Trackable Delivery | $93.00 | Add to cart |
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Primaquine product description
Primaquine, it is released in the form of diphosphate. It is a fine crystalline powder of a bright yellow color, bitter in taste, soluble in water. It has an antiprotozoal effect on the sexual forms, schizonts and para-erythrocytic forms of all forms of malaria plasmoids. Applied for the prevention of long-term recurrences with three- and four-day and tropical malaria. In addition, prescribed for personal chemoprophylaxis in combination with Chingaminum (chloroquine), as well as for public chemoprophylaxis.
Primaquine safety information
Among the population of some areas of the Mediterranean, the Caucasus, and Africa (particularly often) there are people with congenital lack of glucose-6-phosphate dehydrogenase, therefore in these areas the primaquine should be consumed with an extreme caution, not exceeding the daily dose of 0.015 g based on the base (0.027 g diphosphate) for an adult; in the process of treatment, the accurate monitoring of the patient is necessary.
Primaquine should not be taken simultaneously with the Acrichinum (the Primaquine tablet is retained in the blood, and therefore its toxicity enhances) and during the shortest time after taking the Acrichinum (due to the slow release of Acrichinum from the body) and also with drugs that can exert hemolytic action and inhibit myeloid elements bone marrow (sulfonamides, etc.).
Primaquine is contraindicated for persons with acute infectious diseases (except malaria), during an exacerbation of rheumatism and other diseases characterized by a tendency to granulocytopenia, with blood and hematopoietic diseases, kidney illness, angina pectoris. It is impossible to cure with a help of Primaquine simultaneously with drugs that depress hemopoiesis.
Primaquine side effects
In the majority of cases this medical agent is well tolerated, but occasionally during the course of pharmaceutical, there may appear the pain in the abdomen, dyspepsia, pain in the heart; general weakness, cyanosis (methemoglobinemia). These phenomena occur after the drug course is discontinued. Children should get the prescription just being under severe control during the treatment procedure. An acute intravascular hemolysis with the hemoglobinuria may manifest in people with a lack of erythrocyte in the enzyme glucose-6-phosphate dehydrogenase. In severe cases, the picture resembles hemoglobinuric fever.
When prescribing the Primaquine tablets to patients with symptoms of anemia and with suspicion of anemia, an abnormality of red blood cells should be carefully regulated and the examination of the state of the blood and urine should be conducted as well. At the first signs of a change in the color of urine, a sharp decrease in the content of hemoglobin or a change in the number of white blood cells, the course of the treatment with Primaquine has to be immediately canceled.
A peripheral vasodilator, blocks postsynaptic alpha1-adrenergic receptors and prevents the vasoconstrictive influence of catecholamines. It reduces pressure in the pulmonary veins and the right atrium significantly, it also reduces pulmonary vascular resistance moderately. The drug therapeutic indications include: arterial hypertension; CHF (in combination therapy), Raynaud's syndrome and disease, pheochromocytoma, peripheral vascular spasm on the background of poisoning with ergot alkaloids. Prostatic hyperplasia
Cialis Super Active is a generic drug, against erectile dysfunction, containing 20 mg of tadalafil. The tablets in this series have a gel inside. This form allows the active substance, Tadalafil, to immediately enter the blood, thus providing an immediate effect. The result from the Cialis Super Active tablets appears after 5 minutes! The action lasts for two days. The drug is safe and has virtually no contraindications.
Viagra Oral Jelly - a new formula of the drug Viagra. Sildenafil - 100 mg. It is prescribed for men with a weak potentiality. Helps to recover libido and to improve sexual activity. Accelerates process of excitement of reproductive system. It makes erection brighter. Considerably increases duration of sexual intercourse. Besides, drug has various pleasant tastes, it is convenient to carry in a pocket or in a purse. Hurry to try it!
ED Trial Pack (2 Viagra + 2 Cialis + 2 Levitra) - a trial set consists of six tablets, for those who want to understand what medicine is better for him. Includes 6 tablets (by 2 pсs.): Viagra, Cialis and Levitra. It can be taken by people older than 18 years, in case of problems in private life related to fatigue, stress, sleep debt, slow-moving way of life and abuse of addictions.
Brand Viagra - a drug from Pfizer, with a basic chemical called Sildenafil Citrate, is a first developed pharmaceutical to cure the difficulties with erection. It functions approximately within 4-5 hours, must be taken an hour prior to sex.
Clozaril - atypical antipsychotic medicine. Blocks dopamine receptors of CNS and interferes dopamine transfer in basal gangliya and in limbic part of neoncephalon. It is taken at Hypersensitivity, diseases of hemopoietic system (including in anamnesis), alcoholic and toxic psychosis, myasthenia, comas.
Cymbalta drug possesses a central mechanism of suppression of a pain syndrome that first of all can be noticed at increase in a threshold of painful sensitivity at pain syndrome of neuropathic etiology.
Glucotrol peroral hypoglycemic medicine. It is taken at a diabetes mellitus of type 2 (at inefficiency of dietotherapy). It has pancreatic and extra pancreatic effects. Stimulates secretion of insulin by reductions of the threshold of irritation with glucose of beta cells of pancreas, increases sensitivity to insulin and extent of its linkng with target cells, increases insulin release, strengthens influence of insulin on glucose absorption by muscles and liver, brakes lipolysis in fatty tissue.
Fulvicin - the antifungal antibiotic, which is taken at mycosis of skin, hair and nails (favus, trichophytosis, microsporia of a pilar part of the head, microsporia of smooth skin, dermatomycosis of beard and moustaches, epidermophitia of smooth skin, inguinal epidermophitia, onychomycoses). It is effective concerning fungus of the sort Trichophyton, Microsporum, Epydermophyton, Achorionum; causes disturbance of the structure of a mitotic spindle and synthesis of a cell wall at chitin fungus, suppresses division of fungal cells in metaphase and synthesis of protein because of disruption of linking with template-RNA.
Cephalexin - antibacterial agents for systemic use. Cephalosporins of the first generation. Used in the treatment of infections caused by microorganisms susceptible to cefalexin: ENT organs and respiratory tract, genitourinary system, skin and soft tissues, bone tissue and joints.
Tricor - is a hypolipidemic agent, has an uricosuric and antiplatelet effect. In combination with diet therapy, the drug is prescribed for a long-term treatment, the effectiveness of which must be periodically checked by determining serum lipid levels.
A lipid-lowering agent. Reversibly inhibits HMG-COA reductase, inhibits the cholesterol synthesis at the stage of mevinolinic acid and moderately reduces its intracellular concentration. The indications for the drug use include: primary hypercholesterolemia mainly of IIa and IIb types, under the ineffective diet treatment in patients with increased risk of coronary atherosclerosis, hypercholesterolemia combined with hypertriglyceridemia; prevention of coronary artery disease. The drug decreases the risk of myocardial infarction, the need for revascularization of the myocardium, deaths from cardiovascular system diseases.
Gastroprotective agent, a synthetic analog of PgE1 boosts the formation of defensive slime and bicarbonate; enhances blood flow in the mucosa. It stimulates the healing of erosions, gastric and duodenal ulcers and is able to prevent their formation in some cases. It has a direct impact on the parietal cells of the abdomen, inhibits the lowest, and stimulated (by meal,pentagastrin, histamine) excretion of HCl. he drug diminishes the basal production of pepsin. The expected result occurs after 30 minutes and lasts at least 3-6 hours.
