The drug has a thymoleptic and anxiolytic effect. Prescribed for the treatment of depressions of various origins, enuresis including the night one.
Prothiaden
| Package | pill | Total price | Save | Order |
|---|---|---|---|---|
| 75mg × 30 Pills | $0.91 | $27.36 + Bonus - 4 Pills | - | Add to cart |
| 75mg × 60 Pills | $0.79 | $47.65 + Bonus - 4 Pills | $7.20 | Add to cart |
| 75mg × 90 Pills | $0.73 | $65.86 + Bonus - 7 Pills | $16.20 | Add to cart |
| 75mg × 120 Pills | $0.63 | $75.64 + Bonus - 7 Pills | $33.60 | Add to cart |
| 75mg × 180 Pills | $0.60 | $107.84 + Bonus - 11 Pills | $55.80 | Add to cart |
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Prothiaden product description
Prothiaden is a tricyclic antidepressant. It has an antidepressant and anxiolytic effect, which develops on the 3-5th day after one started taking the drug. It also has cholinolytic activity. Indications for use:
Depression (especially with anxiety, agitation and sleep disorders, including in childhood, endogenous, involutional, reactive, neurotic, drug-induced, with organic brain lesions, alcohol withdrawal), schizophrenic psychoses, mixed emotional disorders, behavioral and attention disorders, enuresis (except for patients with bladder hypotonia), incontinence, bulimia nervosa, chronic pain syndrome (chronic pain in cancer patients, migraine, preparation for surgery of patients with elevated the level of anxiety, psychogenic impotence.
The mechanism of antidepressant action is associated with an increase in the concentration of noradrenaline in synapses and/or serotonin in the central nervous system (a decrease in their reverse absorption). Accumulation of these neurotransmitters occurs as a result of inhibition of their inverse capture by the membranes of presynaptic neurons. With prolonged use, the medicine reduces the functional activity of beta-adrenergic and serotonin receptors in the brain, normalizes adrenergic and serotonergic transmission, restores the balance of these systems, disturbed in depressive states. With anxiety-depressive states reduces anxiety, agitation, and depressive manifestations.
Prothiaden safety information
The initial dose is 25-50 mg/day, most of the dose is given before bedtime. The maximum dose is 450 mg (for inpatients). With psychogenic impotence, 25 mg is prescribed at night. The minimum duration of treatment is 3 months. The maximum daily dose for children is 100 mg. The course of treatment with Protiaden starts from 3 months. It is necessary for the dosage to be prescribed by the attending physician, who has information on the patient's general health condition and clearly knows his diagnosis.
Prothiaden is incompatible with MAO inhibitors, phenytoin, adrenoblockers, phenothiazines, benzodiazepines, sympathomimetics, thyroid hormone drugs.
The drug is cautiously prescribed for patients with epilepsy. The drug therapy can be started not earlier than two weeks after stopping the intake of MAO inhibitors. Among the contraindications for taking medication are the following: closed-angle glaucoma, prostate adenoma, obstructive conditions of the digestive system, atony of the bladder, the first trimester of pregnancy.
Prothiaden side effects
Side effects of dozulepin are less common and weaker than in other antidepressants. Among them, there are cases of allergic reactions to the components of the drug, delayed urination, disruption of accommodation, constipation, tachycardia, hypotension, dry mouth, fatigue, drowsiness, dizziness. With prolonged admission, estrogen-like effects are possible. The drug is not used simultaneously with MAO inhibitors, phenytoin, adrenoblockers, phenothiazines, benzodiazepines, sympathomimetics, thyroid hormone preparations. The drug has a thymoleptic and anxiolytic effect.
A peripheral vasodilator, blocks postsynaptic alpha1-adrenergic receptors and prevents the vasoconstrictive influence of catecholamines. It reduces pressure in the pulmonary veins and the right atrium significantly, it also reduces pulmonary vascular resistance moderately. The drug therapeutic indications include: arterial hypertension; CHF (in combination therapy), Raynaud's syndrome and disease, pheochromocytoma, peripheral vascular spasm on the background of poisoning with ergot alkaloids. Prostatic hyperplasia
Clozaril - atypical antipsychotic medicine. Blocks dopamine receptors of CNS and interferes dopamine transfer in basal gangliya and in limbic part of neoncephalon. It is taken at Hypersensitivity, diseases of hemopoietic system (including in anamnesis), alcoholic and toxic psychosis, myasthenia, comas.
Cymbalta drug possesses a central mechanism of suppression of a pain syndrome that first of all can be noticed at increase in a threshold of painful sensitivity at pain syndrome of neuropathic etiology.
Glucotrol peroral hypoglycemic medicine. It is taken at a diabetes mellitus of type 2 (at inefficiency of dietotherapy). It has pancreatic and extra pancreatic effects. Stimulates secretion of insulin by reductions of the threshold of irritation with glucose of beta cells of pancreas, increases sensitivity to insulin and extent of its linkng with target cells, increases insulin release, strengthens influence of insulin on glucose absorption by muscles and liver, brakes lipolysis in fatty tissue.
Fulvicin - the antifungal antibiotic, which is taken at mycosis of skin, hair and nails (favus, trichophytosis, microsporia of a pilar part of the head, microsporia of smooth skin, dermatomycosis of beard and moustaches, epidermophitia of smooth skin, inguinal epidermophitia, onychomycoses). It is effective concerning fungus of the sort Trichophyton, Microsporum, Epydermophyton, Achorionum; causes disturbance of the structure of a mitotic spindle and synthesis of a cell wall at chitin fungus, suppresses division of fungal cells in metaphase and synthesis of protein because of disruption of linking with template-RNA.
Cephalexin - antibacterial agents for systemic use. Cephalosporins of the first generation. Used in the treatment of infections caused by microorganisms susceptible to cefalexin: ENT organs and respiratory tract, genitourinary system, skin and soft tissues, bone tissue and joints.
Tricor - is a hypolipidemic agent, has an uricosuric and antiplatelet effect. In combination with diet therapy, the drug is prescribed for a long-term treatment, the effectiveness of which must be periodically checked by determining serum lipid levels.
A lipid-lowering agent. Reversibly inhibits HMG-COA reductase, inhibits the cholesterol synthesis at the stage of mevinolinic acid and moderately reduces its intracellular concentration. The indications for the drug use include: primary hypercholesterolemia mainly of IIa and IIb types, under the ineffective diet treatment in patients with increased risk of coronary atherosclerosis, hypercholesterolemia combined with hypertriglyceridemia; prevention of coronary artery disease. The drug decreases the risk of myocardial infarction, the need for revascularization of the myocardium, deaths from cardiovascular system diseases.
Gastroprotective agent, a synthetic analog of PgE1 boosts the formation of defensive slime and bicarbonate; enhances blood flow in the mucosa. It stimulates the healing of erosions, gastric and duodenal ulcers and is able to prevent their formation in some cases. It has a direct impact on the parietal cells of the abdomen, inhibits the lowest, and stimulated (by meal,pentagastrin, histamine) excretion of HCl. he drug diminishes the basal production of pepsin. The expected result occurs after 30 minutes and lasts at least 3-6 hours.
The anti-malarial drug from the group of 8-aminohinolina derivatives. It is characterized by intercalation with DNA plasmodia, leading to disruption of nucleic acids synthesis. It demonstrates high activity against exo-erythrocytic forms of all types of malaria, including primary tissue and para- erythrocyte forms. Particularly active against primary tissue forms of Plasmodium falciparum.