Asacol, which is mesalamine - derivative of 5-aminosalicylic acid. It is prsecribed for treatment and remission maintenance at patients with ulcer colitis (earlier known as nonspecific ulcer colitis) of mild and moderate type.
Asacol
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Asacol product description
Drug uses
Asacol is an aminosalicylate drug used to treat inflammatory bowel disease. Asacol tablets are indicated in pediatric patients (aged 5 and above), adults and elders for treatment and prophylaxis of:
- Crohn's ileitis and colitis
- Mildly to moderately active ulcerative colitis
Asacol provides anti-inflammatory and antibacterial action, reduces intestinal inflammation by inhibition of prostaglandin production in the rectum and by blocking of cyclooxygenase activity (an enzyme involved in prostaglandin synthesis).
The characteristic feature of Asacol comparing to other aminosalicylates is its good tolerance and ability to significantly reduce the risk of relapse in Crohn's disease. The recommended adult dose of Asacol in the treatment of active ulcerative colitis is 2.4 grams per day (2 tablets of Asacol three times a day) for 6 weeks.
To maintain remission of mildly to moderately active ulcerative colitis, the recommended dose of Asacol is 1.6 grams per day. The dose of Asacol for children is calculated based on the child's body weight and disease severity. The maximum pediatric dose should not exceed 2.4 grams per day.
Missed dose
During treatment of inflammatory bowel disease, the patients should comply with the prescribed dosage regimen, and try to avoid skipping any pill of the anti-inflammatory drug. However, if the patient forgot to take a dose of the aminosalicylate drug, it should be taken as soon as possible.
To double a dose of the antimicrobial is not recommended. The patient is advised to skip a missed dose, if it is nearly time for the next dose of Asacol. Further treatment of inflammatory bowel disease is conducted under the regular dosage of Asacol.
More information
Asacol can be taken regardless of meals, the pills should be swallowed whole, not split or chewed. To avoid any reduction in the therapeutic efficacy of aminosalicylate, Asacol delayed-release tablets should be protected against moisture. Asacol is not recommended to patients during pregnancy and breastfeeding, as aminosalicylate may adversely affect the baby’s intrauterine development and the breastfed child.
Storage
Asacol tablets should be stored in a dry warm place, away from children, in their original package. The recommended storage temperature is from 15°C to 25°C.
Asacol safety information
Warnings
Coadministration of Asacol with nonsteroidal anti-inflammatory drugs or other nephrotoxic agents may increase the risk of nephrotoxicity. For this reason, extra caution should be taken while indicating Asacol in patients suffering from kidney failure.
Patients with hepatic dysfunction and with mild to moderate renal insufficiency are recommended to take caution whilst taking Asacol. All patients are advised to pass screening of the renal and liver function before starting the treatment of inflammatory bowel disease.
In patients suffering from pyloric stenosis, Asacol tablets may stay in the stomach for long, so aminosalicylate may reaches the colon later than usual. Coadministration of Asacol with 6-mercaptopurine or azathioprine may cause blood disorders, consequently for this reason, their coadministration should be avoided.
Disclaimer
Information about Asacol and treatment of gastrointestinal disorders contained in this review should not be used to replace the gastroenterologist’s consultation. The online pharmacy shall not be liable for consequences of any decisions made or actions based on the use of the review of anti-inflammatory drug Asacol.
Asacol side effects
Treatment with Asacol is usually well tolerated and does not cause any serious adverse effects. Cases of cessation of the drug Asacol use are reported rarely, because all adverse effects, caused by this drug, are characterized by mild transient nature.
Sometimes, while taking Asacol, certain side effects are experienced, most common of them include gastrointestinal adverse effects, such as abdominal pain, diarrhoea, constipation, and nausea. In addition, dizziness, headache and rash can be observed as well.
Cough, nasopharyngitis and sinusitis are considered as the most frequent adverse effects, which may appear in children during treatment with Asacol. Adults also may experience back pain, eructation, rhinitis, and nausea.
An anthelmintic broad-spectrum drug; most effective with enterobioze and trihozefaleze. Causes irreversible violation of glucose utilization, depletes the glycogen stores in the tissues of worms, inhibits the synthesis of cellular tubulin and also inhibits the ATP synthesis.
Vermox - anthelminthic drug of a wide spectrum of action. The most effective for Enterobius vermicularis, Trichuris trichiura, Ascaris lumbricoides, Ancylostoma duodenale, Necator americanus, Strongyloides stercoralis, Taenia solium, Echinococcus granulosus, Echinococcus multilocularis, Trichinella spiralis, Trichinella nativa, Trichinella nelsoni.
Causing an irreversible violation of glucose utilization, depletes glycogen stores in helminth tissues, interferes with the synthesis of cellular tubulin, and also inhibits the synthesis of ATP.
Co-Amoxiclav - co-formulated antibacterial agent, combine of bactericidal antibiotic of a broad spectrum of activity, from a group of semi-synthetic penicillin - Amoxicillin and Betalactamase inhibitor.
A drug for the prevention and treatment of HIV infection. An antiviral agent, which competitively blocks the reverse transcriptase and selectively inhibits the replication of viral DNA.
Promethazine reduces the permeability of capillaries, swelling of the mucous membranes, itching. Has adrenolytic, moderate peripheral and central cholinolytic action. Inhibits histamine-N-methyltransferase, blocks central histamine H3 receptors. Oppresses the central nervous system, has a sedative, anxiolytic, antipsychotic and hypnotic effect, lowers body temperature. Reduces the excitability of the vestibular receptors, eliminates dizziness. Has antiemetic effect.
Clarinex is an antihistamine, anti-allergic, anti-inflammatory drug in the form of tablets. Selectively blocks peripheral histamine H1 receptors. It is used for symptomatic therapy of seasonal and all-year-round allergic rhinitis, chronic idiopathic urticaria.
Aristocort - glucocorticoid drug (the adrenal hormone influencing carbohydrate and protein metabolism). Renders prominent antiinflammatory, antiallergic and immunodepressive (suppressing immunity - body defences of an organism) effect. It is prescribed at rheumatism, allergic reactions, multiform erythema (variously proceeding skin disease which occurs with rubefaction of affected area of skin), pseudorheumatism (the infectious and allergic disease from a group of collagenoses which is characterized by chronic progressing inflammation of joints); systemic lupus erythematosus and other collagenoses.
Eskalith - mood stabilizing agent (normalizes a mental state, without causing the general block), renders also antidepressive, sedative and anti-maniacal action. It is prescribed at maniacal and hypomaniacal states of various genesis, affective psychoses, alcoholism, migraine, Menyer's syndrome, sexual frustration, medicinal dependence.
The medicine is blue or white tablets, the dose of the active substance is 75, 100 and 150 mg. Tablets have the bitter taste and a slight anesthetic effect on the oral mucosa. Pills may be quickly dissolved in water. Bupron is a second-generation antidepressant. Its effectiveness as an anti-nicotine drug is based on the suppression of psychological dependence on nicotine (nicotine dependence), as well as on the direct antidepressant effect, which reduces the negative manifestations that appear when a person gives up smoking.
Antidepressant. Strengthens the central adrenergic and serotonergic transfer. Used for the treatment of depressions including anhedonia, psychomotor retardation, insomnia, early awakening, weight loss, loss of interest in life, suicidal thoughts and mood swings.
Fulvicin - the antifungal antibiotic, which is taken at mycosis of skin, hair and nails (favus, trichophytosis, microsporia of a pilar part of the head, microsporia of smooth skin, dermatomycosis of beard and moustaches, epidermophitia of smooth skin, inguinal epidermophitia, onychomycoses). It is effective concerning fungus of the sort Trichophyton, Microsporum, Epydermophyton, Achorionum; causes disturbance of the structure of a mitotic spindle and synthesis of a cell wall at chitin fungus, suppresses division of fungal cells in metaphase and synthesis of protein because of disruption of linking with template-RNA.
Grifulvin V - the antifungal antibiotic, which is taken at mycoses of skin, hair and nails, and effective concerning fungus of the sort Trichophyton, Microsporum, Epydermophyton, Achorionum; causes disturbance of structure of mitotic spindle and synthesis of a cell wall in chitin fungus, suppresses division of fungal cells in metaphase and synthesis of protein because of disruption of linking with template-RNA.
Diflucan - antifungal medicine, possesses highly specific action, inhibiting activity of enzymes of fungus. It is taken at systemic lesions caused by fungus including meningitis, sepsis, infections of lungs and skin as at patients with a normal immune response, and at patients with various forms of immunosuppression.
Famvir - antiviral medicine which is taken for prevention and treatment of herpes at primary infection, post-herpetic neuralgia, recurrent genital herpes. Pro-medicine; represents a 6-deoxysidiacetil analog of active antiviral agent of a penciclovir.
Zyvox is a synthetic medicine with the increased antibacterial effectiveness. It is mostly used in the treatment of pulmonary and skin diseases caused by a wide range of Gram-positive species. In current medicinal practice, Zyvox often plays a role of the drug of last resort, since it is intended for use in people suffering from multidrug-resistant infections. The extremely high efficiency of this medicine makes it a popular choice in the treatment of severe bacterial infections and simultaneously limits its use against low-hazard infections in order to avoid propagation of resistant microorganisms.
Cefadroxil - cephalosporin antibiotic of the I generation for intake. It works as bactericidal, breaking synthesis of a cell wall of microorganisms. It has a broad spectrum of activity: it is active in relation as gram-positive (Staphylococcus spp. which don't produce and produce a penicillinase; Streptococcus spp. (including Streptococcus pneumoniae), Corynebacterium diphtheriae, Bacillus anthracis), and gram-negative microorganisms (Shigella spp., Salmonella spp., Escherichia coli, Haemophilus influenzae, Klebsiella spp., some strains of Proteus spp., especially Proteus mirabilis), Moraxella catarrhalis (Branhamella). Many strains of Enterococcus faecalis and Enterococcus faecium are steady against Cefadroxil.
Cephalexin - antibacterial agents for systemic use. Cephalosporins of the first generation. Used in the treatment of infections caused by microorganisms susceptible to cefalexin: ENT organs and respiratory tract, genitourinary system, skin and soft tissues, bone tissue and joints.
Tetracycline has a wide range of antibacterial activity. It interferes with the formation of a complex between the transport RNA and the ribosome, which leads to a violation of protein synthesis by a microbial cell. Active in relation to most gram-positive and gram-negative bacteria, spiophets, leptospires, rickettsiaes, trachomae pathogens, ornithosis, and large viruses.
Chloromycetin - the Antibiotic of a broad spectrum of activity. The mechanism of antimicrobic action is connected with disturbance of protein synthesis of microorganisms. It has bacteriostatic action. It is active concerning gram-positive bacteria. Chloromycetin is active concerning the strains steady against penicillin, streptomycin, streptocides.
Dipyridamole medicine for treatment and prevention of thrombosis and thromboembolism, prevention of occlusion of stents and aortocoronary shunts. Expands coronary vessels (preferential arterioles) and causes significant increase in volume speed of a blood velocity. Increases the level of oxygen in a venous blood of a coronary sine and its absorption by a myocardium.
Non-selective beta-blocker. Has antianginal, hypotensive and antiarrhythmic effect. It is used for arterial hypertension, angina pectoris, unstable angina, sinus tachycardia, supraventricular tachycardia, tachyarrhythmia, extrasystole.
It is a sulfonamide diuretic that is pharmacologically related to thiazide diuretics. The medicine inhibits sodium reabsorption in the cortical segment of the kidneys. It increases the excretion of sodium and chlorides in the urine and the excretion of potassium and magnesium, thus increasing diuresis. The antihypertensive effect of the active components appears at doses at which the diuretic effect is insignificant. Moreover, its antihypertensive effect persists even in patients with hypertension.
Tricor - is a hypolipidemic agent, has an uricosuric and antiplatelet effect. In combination with diet therapy, the drug is prescribed for a long-term treatment, the effectiveness of which must be periodically checked by determining serum lipid levels.
Extra Super Avana is the medicine that is aimed to treat erectile dysfunction in men. It’s a combination of Avanafil and Dapoxetine. The erection is the result of muscle relaxation and increased blood flow to men’s genitals. Strong pressure provokes strong erection that can last up to 8 hours. Men also take the drug to prevent premature ejaculation. It’s one of Viagra analogs. The difference is in their main ingredients. Thanks to that a patient has an opportunity to avoid allergy by substituting one active component with the other.
Super Kamagra - Ajanta product combining two active substances: sildenafil, with a dosage of 100 mg, and dapoxetine, with a dosage of 60 mg. Such a successful mix of these elements helps men who have some potency disorders to fix 2 difficulties at once: 1 - connected with an erection, another - with premature ejaculation.
Aurogra is the erectile dysfunction drug that belongs to Viagra analogs. The drug is also taken in case of premature ejaculation and enlarged prostate. The drug is prescribed when erectile dysfunction occurs naturally (due to aging) and if it’s the result of bad habits (smoking, alcohol abuse, drug dependence) and diseases. Its main component is Sildenafil Citrate. It’s created to stimulate the natural process of erection in men. Blue diamond pills make the blood flow to the pelvic area and cause a stable erection. The effect of each pill is strong and lasts up to 5 hours.
Zenegra is a generic Sildenafil-containing medicine intended for use in urology – for the most part in the treatment of erectile dysfunctions of different origin. The drug provides regulation of the enzymic activity of the specific phosphodiesterase and releases nitric oxide that provides the muscle-relaxing effect. The active ingredient also maintains a certain level of blood pressure in the penis, providing a proper erectile response. The usual effect lasts no less than 4 hours; however, some patients report 18 and more hours of increased sexual arousal.
Premature ejaculation (PE) is a distressing male sexual dysfunction that can be present from the first sexual encounter or can develop later in life. Men with premature ejaculation appear to go through the same process of ejaculation as other men, but it happens more quickly and with a reduced feeling of control.
Kamagra - a pharmaceutical remedy for the readiness of a male sexual organ for a sex, provided by the generics maker named Ajanta, perceptibly balances the male aplomb and is one of the best replacements of Viagra.
Brand Levitra – a drug from Bayer, with a basic chemical called Vardenafil, is an improved remedy for treating erectile difficulties. Operates approximately within 6-8 hours, so a man may be ready to perform sexually the whole night.
Tadora is a relatively new medicine designed for prevention of the erectile failure. It contains the same active ingredient as the majority of other drugs used in current medicinal practice – Tadalafil, though its mechanism of action is not identical. The main difference, which is simultaneously the main advantage of the medicine, is its prolonged half-life. It is often called a “weekend pill” because it may work for 36-48 hours, creating favorable conditions for a normal intercourse. It can be recommended for men suffering from various forms of impotence, especially those requiring prolonged therapeutic action.
Florinef is a brand name of Fludrocortisone. It is a corticosteroid produced to treat adrenogenital syndrome (also called Apera-Galle syndrome), Addison's disease, orthostatic hypotension, cerebral salt wasting syndrome, and adrenal insufficiency. The drug replenishes the deficiency of hormones of the adrenal cortex. 1 tablet contains 0.1 mg of fludrocortisone acetate. It participates in the metabolism, including mineral and carbohydrate one. The drug causes the retention of sodium ions and promotes the excretion of potassium.
stimulant of the intestinal peristalsis. Motillium is assigned in cases of: distention, overeating, vomiting, heartburn, flatulence, a feeling of overflow of the stomach.
An antimicrobial bactericide - synthetic derivative of nitroimidazole. Used in urethritis, vaginitis, intestinal amoebiasis, liver amoebiasis, giardiasis.
Antiepileptic agent; binds to the additional subunit (a2-delta protein) of the potential-dependent Ca2 + -channels in the CNS, which promotes the manifestation of analgesic and anticonvulsant action. Reduction in the frequency of seizures begins within the first week.
Aldactone, which is spironolactone - is a competitive antagonist of aldosteron. In disteel kidney tubules increases removal of sodium and water, reduces - potassium. Lowers arterial pressure. It is prescribed at hyperaldosteronism, diagnostics of hyperaldosteronism, adenoma of adrenal glands, producing aldosterone; edema syndrome at chronic heart failure, cirrhosis, nephrotic syndrome, nephropathy of pregnant women; arterial hypertension, hypokalaemia, as additional medicine at malignant hypertension, hypokalaemia, prevention of hypokalaemia at patients with cardiac glycoside.
The anti-malarial drug from the group of 8-aminohinolina derivatives. It is characterized by intercalation with DNA plasmodia, leading to disruption of nucleic acids synthesis. It demonstrates high activity against exo-erythrocytic forms of all types of malaria, including primary tissue and para- erythrocyte forms. Particularly active against primary tissue forms of Plasmodium falciparum.
Rogaine is the brand recommended by trichologists all over the world for hair restoration. For more than 20 years, the medicine has shown excellent results, which are confirmed in more than 2000 clinical trials. Using Rogaine 5 one is able to grow new hair and stop further hair loss. The lotion has no smell and is easy to use. The medicine is a great discovery that stops baldness and regains self-confidence. Rogaine lotion Extra Strength 5% Minoxidil stimulates the growth of new healthy hair. The first signs of growth appear after 2-3 months of regular use of the drug.
Propecia - an anti-hormonal drug. Used to reduce the size of the prostate gland, to increase the maximum speed of urine outflow, reducing the risk of developing acute urinary retention. The drug also turned out to be effective in the treatment of men’s alopecia.
Tenorminis a cardioselective beta-adrenoblocker. It is based on a substance called Atenolol, which blocks nerve impulses, which leads to a decrease in the frequency and strength of the heartbeat. Atenolol has antihypertensive (lowers pressure), antianginal (eliminates the symptoms of myocardial ischemia) and antiarrhythmic (eliminates heart rhythm disturbances) by action.
Combined oral contraceptives block the action of gonadotropins. The first effect of these drugs is aimed to inhibit ovulation. The drug leads to modifications in cervical mucus. Thus, it is strenuous for sperm to pass to the uterine cavity and affect the uterine lining, thereby reducing the possibility of implementation. It helps to prevent pregnancy. Moreover, oral contraceptives prevent pregnancy and have a number of advantages. They have an impact on the cycle of menses and it becomes regular. The amount of blood loss at the time of menstruation is shorter as well as the loss of iron, dysmenorrhea is rare.
Zestril is an angiotensin-converting enzyme inhibitor (ACE). It works by relaxing the blood vessels. This helps lower blood pressure. It is used in the treatment of high blood pressure, alone or in conjunction with other medicines.
Bystolic is an anti-anginal, antihypertensive anti-arrhythmic drug. It stimulates the internal surface of the blood vessels (endothelium) for the production of nitric oxide, which also helps the vessels to relax. It is used for hypertension, IHD, Stenocardia tension.
Gasex arranges the work of the intestine and reduces the time of digestion process. The drug acts as spasmolytic, antiulcerant, anti-inflammatory agent, cholagogue, hepatoprotective agent, membrane-modulating agent, an antimicrobial agent, and antioxidant. The drug also improves the digestibility of vitamins. It’s used for symptomatic control and relief of dyspepsia (upset stomach). The drug is used in case of flatulence, bloating, belching and for preliminary radiographic preparation of the intestine for radiography. The pills cope with discomfort in the abdomen in the postoperative period or during prolonged immobilization.
Diabecon is aimed at increasing peripheral glucose intake, restoring B cells, increasing C – peptide levels. Diabecon has antioxidant properties, protecting cells from oxidative stress. The drug eliminates the painful symptoms of diabetes: polyuria, fever, burning feet and hands. Symptoms are eliminated not immediately after administration but within two to three weeks. This is due to changes in chemical processes in the body that cause symptoms of the disease. Diabecon naturally reduces craving for sweets, restores the patient's appetite, normalizes the functions of liver and kidney.
Penegra drug, which can be ordered in an online pharma shop without the RX, is made by Zydus Fortiza (located in India), a major chemical plant producing remedies for potency. The preparation is designed in the form of pills, sorted in blisters for 4 pcs. Penegra, as a generic version of the well-known blue tablet, is used both, at the initial stage, and in severe cases of an impotence.
Hytrin refers to the group of pharmaceutical products intended to cure the sexual/urinary maladies and sex hormone medical preparations. Its composition includes Terazozin - a medical mean for the normalization of the prostate gland in benign hypertrophy.
Avodart – special medical remedy, also named Dutasteride, refers to urological drugs. A considerable number of men who are at the age of fifty and older address a urologist for the occurrence of a micturition disorder due to benign prostatic hyperplasia. Avodart capsules help to overcome this malady.
Trileptal is used to treat simple and complex forms of partial epileptic seizures that have secondary generalization (possibly without it) beginning at the age of one month; generalized tonic-clonic forms of epileptic seizures in patients from two years of age. Reviews about Trileptal have a positive connotation, which allows to determine its effectiveness in use, thanks to patients who have experience of taking the drug.
Haldol antipsychotic remedy, butyrophenone derivative. It has a powerful antipsychotic effect, moderate sedation. The mechanism of antipsychotic action of haloperidol is associated with the blockade of dopamine receptors in the mesocortex and limbic system.
Coumadin is a drug that promotes blood thinning in the veins. Within a short period of application, anticoagulant reduces viscous blood consistency and lowers the risk of blood clots. The drug is prescribed only after laboratory blood tests when certain symptoms are detected. Independent use of tablets is prohibited, only a doctor may establish the need for taking the drug. Thrombosis is a disease that is characterized by the formation of blood clots. In case of delayed treatment, this disease may cause disorders of oxygen metabolism in the blood and embolism.
Xalatan is a chemical analog of the hormone prostaglandin. It is a topical agent available in the form of eye drops with a concentration of latanoprost 50 mcg/ml. Its mode of action is similar to the one of its natural equivalent – the drug increases the flow of intraocular fluid from the hypertensive eyeball. As a result, the pressure in the eyeball slowly decreases. Since this symptom frequently accompanies various eye diseases, Xalatan is often prescribed in combination with other medicines. Today, this drug is among the high-priority agents in the treatment of such an ubiquitous disease as glaucoma.
Elavil - antidepressive medicine. Renders also some analgesic, H2-histamineblocking and antiserotonin action, promotes elimination of bedwetting and reduces appetite. It is taken at Depressions (especially with anexiety, agitation and sleep disorders, including children's age, endogenous, involutional, reactive, neurotic, medicinal, at organic lesions of a brain, alcoholic abstinence), schizophrenic psychoses, mixed emotional frustration, behavior disorders, night enuresis, nervous bulimia, chronic pain syndrome.
Baclofen is a central muscle relaxant. It is assigned if the patient is diagnosed with spasticity in multiple sclerosis, strokes, craniocerebral trauma, meningitis, spinal diseases (infectious, degenerative, tumor and traumatic genesis), with infantile cerebral palsy; alcoholism
Zanaflex (tizanidine) - the drug with an antispastic effect in increased muscle tone, relieves spasms and clonic convulsions.
Assign with painful muscular spasms associated with static and functional spine lesions (cervical and lumbar syndrome), and after surgery for a herniated disc or osteoarthritis of the thigh, as well as for spasms and pain due to multiple sclerosis, chronic myelopathy, degenerative diseases of the spinal cord brain, stroke, with cramps of central origin.
Accutane, which is isotretinoin, - is a form of vitamin A, belongs to the group of retinoids. It is often used to treat complex, neglected forms of acne, when the remaining anti-acne drugs do not have a positive effect on the treatment of acne. Accutane inhibits the production of sebum and reduces the size of the gums with the main active substance isotretinoin. It is proved that isotretinoin has an antiseptic effect. Also, isotretinoin thinens the stratum corneum of the epidermis to more easily penetrate deep into the affected area. Due to the fact that Accutane suppresses the sebum secretion by reducing the sebaceous glands themselves, this allows to reduce the migration of bacteria in the ducts. And due to the fact that the stratum corneum is thin, the skin fat has an outlet to the outside, from which there is no blockage of the pores and, as a result, pimples.
Deltasone - renders an antiinflammatory, antiallergic, antishock and immunodepressive effect. It is taken for treatment of acute and chronic inflammatory diseases of joints, acute asthma, allergic diseases, skin diseases.
Enzymes for inward, affect edema of instigative and non-inflammatory origin (traumatic, sports). Animal studies have shown the anti-inflammatory characteristics of Benzac and mixed enzyme preparations in oral administration. In numerous animal studies, bromelain and trypsin suppressed platelet aggregation. Healthy volunteers who received a combination these substances were not observed to have a violation of the system of the ability of blood to thicken.
Xeloda is a cytostatic drug. The drug is used for the treatment of patients with metastatic or locally advanced breast cancer, including after an ineffective chemotherapy course, which included anthracycline drugs and taxanes, and also if the patient has contraindications to anthracyclines.
An antineoplastic, antiestrogen remedy. Used to treat breast cancer, mammary gland cancer, carcinoma in situ of the ductal breast cancer; endometrial cancer; estrogenconsisting tumors; adjuvant treatment of breast cancer. It inhibits estrogen receptors competitively in the target organs and tumors originating from these organs.