Zestoretic - tablets containing 12,5Mg of Hydrochlorothiazide and 10Mg of Lisinopril, as active ingredients. It is hypotensive, vasodilating, natriuretic, cardioprotective medical preparation.The drug is used to treat arterial hypertension, also in order to reduce the risk of cardiovascular disease and mortality in patients with hypertension and left ventricular hypertrophy, manifesting cumulative reduction in the incidence of cardiovascular death, incidence of stroke and myocardial infarction.
Zestoretic
| Package | pill | Total price | Save | Order |
|---|---|---|---|---|
| 5/12.5mg × 30 Pills | $1.21 | $36.43 + Bonus - 4 Pills | - | Add to cart |
| 5/12.5mg × 60 Pills | $0.95 | $56.72 + Bonus - 4 Pills | $15.60 | Add to cart |
| 5/12.5mg × 90 Pills | $0.86 | $77.03 + Bonus - 7 Pills | $31.50 | Add to cart |
| 5/12.5mg × 120 Pills | $0.83 | $99.12 + Bonus - 7 Pills | $45.60 | Add to cart |
| 5/12.5mg × 180 Pills | $0.77 | $138.43 + Bonus - 11 Pills | $79.20 | Add to cart |
| 5/12.5mg × 270 Pills | $0.74 | $200.26 + Bonus - 11 Pills Free Trackable Delivery | $126.90 | Add to cart |
| 5/12.5mg × 360 Pills | $0.73 | $261.85 + Bonus - 11 Pills Free Trackable Delivery | $172.80 | Add to cart |
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Product description
Drug uses
Zestoretic is an oral drug, containing two antihypertensive agents, Lisinopril and Hydrochlorothiazide. Due to the combination of the two active ingredients, Zestoretic has a dual mechanism of action.
- Lisinopril lowers high arterial pressure by widening blood vessels.
- Hydrochlorothiazide helps control high blood pressure through diuresis simulation.
Zestoretic is approved for the second-line hypertension treatment in patients, who fail controlling blood pressure with drugs for hypertension monotherapy.
By promoting vasodilation and diuresis, Zestoretic tablets provide a quick, powerful and long-lasting antihypertensive effect.
Taking note of this fact, the patients require regular blood pressure monitoring in early days of Zestoretic treatment. The daily dose of this antihypertensive drug should be reduced, if Zestoretic causes hypotension.
Zestoretic is recommended for once-daily hypertension therapy. The daily Zestoretic dose is one tablet of Zestoretic 10 or Zestoretic 20. Adjustment of antihypertensive therapy is recommended not earlier than 14 days after the starting dose of Zestoretic.
Missed dose
One missed Zestoretic dose does not affect the effectiveness of the antihypertensive therapy. If you missed one dose of Zestoretic, skip it and continue with your normal schedule of this drug use. You should not take more than one Zestoretic 20 pill per day, even if you’ve missed two or more Zestoretic doses in a row.
More information
You should stop using other diuretics and vasodilators before using Zestoretic pills. Zestoretic should be taken with caution by people with moderate or progressive liver disease.
Storage
Zestoretic tablets should be stored in a tightly sealed bottle or the original blister packing, at temperature below 30°C. If a blister with Zestoretic pills was removed from the primary packaging, it should be protected from strong light.
Safety information
Warnings
Using Zestoretic during pregnancy creates a serious threat to the normal fetus development. Therefore, the women of childbearing age should use reliable contraception methods throughout the treatment period with Zestoretic tablets. Zestoretic and other diuretics or vasodilators should be stopped immediately, if you detected pregnancy, when going through the antihypertensive therapy.
Disclaimer
Information about the antihypertensive drug Zestoretic is published for general information purposes only. In no event is the online pharmacy liable for any consequences, arising from the use of or restricted access to information about Zestoretic.
Zestoretic side effects
Zestoretic causes undesirable effects very rarely. Clinical studies have demonstrated that approximately 5-7% of patients, taking Zestoretic tablets, have mild headaches or dizziness. Less than 4% of patients may experience fatigue, cough, orthostatic effects, hypotension, when going through treatment with Zestoretic. Zestoretic may rarely cause syncope or muscle cramps.
Just over 4% of the total number of patients, participating in clinical trials for Zestoretic, had to stop taking Zestoretic tablets due to serious unwanted effects. The most frequent reasons for Zestoretic cancellation due to side effects include excessive fatigue, uncontrollable muscle spasm, dizziness, persistent cough.
In case of an arterial hypertension of Atacand causes dose-dependent long lowering of arterial pressure. Anti-hypertensive action happens due to decrease in system peripheric resistance without reflex increase in heart rate. Instructions on serious or strengthened hypotension after taking of the first dose or Withdrawal Effect after termination of treatment are absent.
Co-Amoxiclav - co-formulated antibacterial agent, combine of bactericidal antibiotic of a broad spectrum of activity, from a group of semi-synthetic penicillin - Amoxicillin and Betalactamase inhibitor.
Allopurinol - a drug that promotes the excretion of uric acid and the removal of urinary calculi.
Clozaril - atypical antipsychotic medicine. Blocks dopamine receptors of CNS and interferes dopamine transfer in basal gangliya and in limbic part of neoncephalon. It is taken at Hypersensitivity, diseases of hemopoietic system (including in anamnesis), alcoholic and toxic psychosis, myasthenia, comas.
Advair Diskus is a drug manufactured to cope with diseases which attack bronchi and lungs. Medics prescribe it for people with COPD, pant, wheeze, dyspnea, pulmonary emphysema, and chronic bronchitis. It consists of two main components: a corticosteroid (Fluticasone) and a long-acting beta agonist (Salmeterol). The first component reduces the irritation and the swelling of lungs and bronchi. The second component makes the breathing easier. Doctors prescribe the drug for patients who need a combination treatment when one medication doesn’t work. The medicine is a part of a long-term medication as it isn’t effective in case of sudden asthma attacks.
Promethazine reduces the permeability of capillaries, swelling of the mucous membranes, itching. Has adrenolytic, moderate peripheral and central cholinolytic action. Inhibits histamine-N-methyltransferase, blocks central histamine H3 receptors. Oppresses the central nervous system, has a sedative, anxiolytic, antipsychotic and hypnotic effect, lowers body temperature. Reduces the excitability of the vestibular receptors, eliminates dizziness. Has antiemetic effect.
Clarinex is an antihistamine, anti-allergic, anti-inflammatory drug in the form of tablets. Selectively blocks peripheral histamine H1 receptors. It is used for symptomatic therapy of seasonal and all-year-round allergic rhinitis, chronic idiopathic urticaria.
The medicine is blue or white tablets, the dose of the active substance is 75, 100 and 150 mg. Tablets have the bitter taste and a slight anesthetic effect on the oral mucosa. Pills may be quickly dissolved in water. Bupron is a second-generation antidepressant. Its effectiveness as an anti-nicotine drug is based on the suppression of psychological dependence on nicotine (nicotine dependence), as well as on the direct antidepressant effect, which reduces the negative manifestations that appear when a person gives up smoking.
Sinequan - antidepressant, which is taken as prescribed by the doctor in case of the following indications: depression, anxiety and sleep disturbance in neuroses, alcoholism, organic diseases of the central nervous system, psychoneurotic disorders with anxiety, depression, psychotic depression (including the involutionary, reactive depressive phase of manic-depressive Psychosis). In general therapeutic practice - duodenal ulcer, dumping syndrome, premenstrual syndrome, chronic pain in cancer patients, skin itching, chronic idiopathic urticaria.
Januvia - is a drug for adult patients with type 2 diabetes mellitus, in order to control the glycemic level under conditions of monotherapy as part of combined treatment regimens. The drug is prescribed to patients with ineffectiveness of diet therapy in combination with optimal physical activity, with the impossible use of metformin because of its intolerance.
Glucotrol peroral hypoglycemic medicine. It is taken at a diabetes mellitus of type 2 (at inefficiency of dietotherapy). It has pancreatic and extra pancreatic effects. Stimulates secretion of insulin by reductions of the threshold of irritation with glucose of beta cells of pancreas, increases sensitivity to insulin and extent of its linkng with target cells, increases insulin release, strengthens influence of insulin on glucose absorption by muscles and liver, brakes lipolysis in fatty tissue.
Fulvicin - the antifungal antibiotic, which is taken at mycosis of skin, hair and nails (favus, trichophytosis, microsporia of a pilar part of the head, microsporia of smooth skin, dermatomycosis of beard and moustaches, epidermophitia of smooth skin, inguinal epidermophitia, onychomycoses). It is effective concerning fungus of the sort Trichophyton, Microsporum, Epydermophyton, Achorionum; causes disturbance of the structure of a mitotic spindle and synthesis of a cell wall at chitin fungus, suppresses division of fungal cells in metaphase and synthesis of protein because of disruption of linking with template-RNA.
Diflucan - antifungal medicine, possesses highly specific action, inhibiting activity of enzymes of fungus. It is taken at systemic lesions caused by fungus including meningitis, sepsis, infections of lungs and skin as at patients with a normal immune response, and at patients with various forms of immunosuppression.
An antifungal agent from the group of imidazole derivatives for external and local applications reduces the synthesis of ergosterol, which is a part of the cell membrane of the microbial wall and leads to a change in its structure and properties. In fungicidal concentrations, it interacts with mitochondrial and peroxidase enzymes, leading to an increase in the concentration of hydrogen peroxide to toxic levels, which also contributes to the destruction of fungal cells. The pills are active against pathogenic dermatophytes, pathogens of multi-colored lichen, erythrasma, gram-positive and gram-negative bacteria.
Famvir - antiviral medicine which is taken for prevention and treatment of herpes at primary infection, post-herpetic neuralgia, recurrent genital herpes. Pro-medicine; represents a 6-deoxysidiacetil analog of active antiviral agent of a penciclovir.
Cephalexin - antibacterial agents for systemic use. Cephalosporins of the first generation. Used in the treatment of infections caused by microorganisms susceptible to cefalexin: ENT organs and respiratory tract, genitourinary system, skin and soft tissues, bone tissue and joints.
Erythromycin is a macrolide antibiotic of bacteriostatic action. In high concentrations and relatively high-sensitivity microorganisms may have a bactericidal effect.
It is a sulfonamide diuretic that is pharmacologically related to thiazide diuretics. The medicine inhibits sodium reabsorption in the cortical segment of the kidneys. It increases the excretion of sodium and chlorides in the urine and the excretion of potassium and magnesium, thus increasing diuresis. The antihypertensive effect of the active components appears at doses at which the diuretic effect is insignificant. Moreover, its antihypertensive effect persists even in patients with hypertension.
The medicine is used for the temporary correction of male erectile disorders. It represents the last generation of drugs for men, as it was developed less than 10 years ago and has the most modern composition than the previous tablets for treating of potency.Avanafil is an active substance of the drug.In the process of excitation in the cavernous body of the male sexual organ,, it relaxes the arteries and vessels to increase blood flow in the right places. The enzyme FDE-5 in some cases disrupts the natural process, not allowing accumulating cGMP to the required level.
Super Kamagra - Ajanta product combining two active substances: sildenafil, with a dosage of 100 mg, and dapoxetine, with a dosage of 60 mg. Such a successful mix of these elements helps men who have some potency disorders to fix 2 difficulties at once: 1 - connected with an erection, another - with premature ejaculation.
Viagra Professional - Advantage of Professional Viagra from usual Viagra is that it works twice longer (6 - 8 hours) and has a stronger effect. Strengthens desire, improves brightness of sexual feelings and increases duration of sexual intercourse.
Viagra Super Active - an innovative formula of drug for treatment of erectile dysfunction. Drug is produced in gelatin capsules that allows to avoid emergence of heartburn or other unpleasant feelings in a stomach. Sildenafil Super Active also has a number of advantages. It is soaked quicker and works longer. The principle of action is identical with ordinary Sildenafil. Each capsule contains about 100 mg of active ingredient. That is quite enough for any man.
Suhagra If one has difficulties with a masculine power, we’d suggest buying Suhagra® a drug of an Indian enterprise, named Cipla, founded back in 1937. It is an exact Viagra® copy, a well-known worldwide medical mean targeted to eliminate the ED problems. Still, Suhagra® is not a Generic Drug. It is a completely independent brand pharmaceutical product that has been verified by all needed health organizations in developed countries. One can buy Suhagra® in 180 countries around the globe. This is an evidence of the reliability and safety of the good.
With Sildigra, the same traditional active ingredients of ED medications provide even more invigoration. The drug’s dynamics is based on the muscle-relaxing effect of nitric oxide. This natural substance receives a boost, while PDE5, the substance that obstructs erections, becomes depressed. The resulting effect manifests as a strong, long-lasting erection that can be adequately maintained throughout the entire intercourse. The pharmaceutical formula of Sildigra includes classic Sildenafil citrate and demonstrates efficiency on the level of branded Viagra.
Premature ejaculation (PE) is a distressing male sexual dysfunction that can be present from the first sexual encounter or can develop later in life. Men with premature ejaculation appear to go through the same process of ejaculation as other men, but it happens more quickly and with a reduced feeling of control.
An antimicrobial bactericide - synthetic derivative of nitroimidazole. Used in urethritis, vaginitis, intestinal amoebiasis, liver amoebiasis, giardiasis.
Methocarbamol – a muscle relaxant used to treat muscle spasms and pain. Its action is to block pain nerve impulses sent to the brain. The mechanism of action is not completely clear. The drug has no direct effect on skeletal muscles. It's likely that its effect is associated with sedative properties.
Thorazine - the product of GlaxoSmithKline and Zuellig Pharma, based on the Chlorpromazine, the substance which belongs to a neuroleptic group of aliphatic derivatives of phenothiazine. It has a pronounced antipsychotic effect, eliminates psychomotor agitation, reduces fear, aggressiveness, psychomotor inhibition. In addition to neuroleptic and sedative, it has antiemetic, hypothermic, antihypertensive, antihistamine and antiserotonin effect. It blocks central adrenergic and dopaminergic interneural contacts. Potentsiruet action of analgesics, local anesthetics, hypnotics and anticonvulsants.
Olanzapine is an antipsychotic drug (neuroleptic). It is shown in schizophrenia in adults, psychotic disorders, bipolar affective disorder in adults, depressive states.
Enalapril is an angiotensin converting enzyme inhibitor (or ACE inhibitor); administered in hypertensive pediatric patients (from 1 month old and above), adults and elderly patients for treatment
Rogaine is the brand recommended by trichologists all over the world for hair restoration. For more than 20 years, the medicine has shown excellent results, which are confirmed in more than 2000 clinical trials. Using Rogaine 5 one is able to grow new hair and stop further hair loss. The lotion has no smell and is easy to use. The medicine is a great discovery that stops baldness and regains self-confidence. Rogaine lotion Extra Strength 5% Minoxidil stimulates the growth of new healthy hair. The first signs of growth appear after 2-3 months of regular use of the drug.
Finpecia - potent pharmaceutical agent aimed to cure an illness named alopecia, of an androgenic as well as a hereditary genesis. Moreover, it stops the manifestation of various maladies deteriorating the advancement of the follicles and other difficulties connected with baldness.
Tenorminis a cardioselective beta-adrenoblocker. It is based on a substance called Atenolol, which blocks nerve impulses, which leads to a decrease in the frequency and strength of the heartbeat. Atenolol has antihypertensive (lowers pressure), antianginal (eliminates the symptoms of myocardial ischemia) and antiarrhythmic (eliminates heart rhythm disturbances) by action.
Atorlip-10 belongs to the drugs which reduce the level of low-density lipoprotein and triglycerides. Doctors identify the level with the help of blood tests. If the level is rather high, then the patients are prescribed the pills. Heart attack, strokes, high blood pressure, diabetes, and other cardiovascular diseases can be prevented thanks to the medicine. The pills are effective in case the disease is acquired due to the improper way of living or when it’s inherited.
Gasex arranges the work of the intestine and reduces the time of digestion process. The drug acts as spasmolytic, antiulcerant, anti-inflammatory agent, cholagogue, hepatoprotective agent, membrane-modulating agent, an antimicrobial agent, and antioxidant. The drug also improves the digestibility of vitamins. It’s used for symptomatic control and relief of dyspepsia (upset stomach). The drug is used in case of flatulence, bloating, belching and for preliminary radiographic preparation of the intestine for radiography. The pills cope with discomfort in the abdomen in the postoperative period or during prolonged immobilization.
Diabecon is aimed at increasing peripheral glucose intake, restoring B cells, increasing C – peptide levels. Diabecon has antioxidant properties, protecting cells from oxidative stress. The drug eliminates the painful symptoms of diabetes: polyuria, fever, burning feet and hands. Symptoms are eliminated not immediately after administration but within two to three weeks. This is due to changes in chemical processes in the body that cause symptoms of the disease. Diabecon naturally reduces craving for sweets, restores the patient's appetite, normalizes the functions of liver and kidney.
Tadapox includes two medications combined for an even more effective approach of the problem of erectile dysfunction. The first one, Tadalafil, is a mighty restorative agent that reverses a male’s inability to achieve a satisfyingly firm erection. The second component, Dapoxetine, handles the other side of clinical impotency that shows as untimely ejaculation. Tadapox successfully manages said issues in populations of patients from 18 to 64 years of age. Its unique mix of therapeutic characteristics helps men revitalize their sexual function in a comparatively short time.
Doxazosin is used for treating hypertension (high blood pressure) and enlarged prostate. The drug increases the blood flow by expanding the veins and arteries. It also relaxes the muscles of the prostate and the neck of urinary bladder, making it easier to urinate.
The medicine is a cardioselective blocker of beta-1-adrenergic receptors. A major risk index for glaucomatous scotoma is an increased tension. When its rate is soaring, the eyes are more damaged. As a consequence, a visual field narrows. Betoptic reduces both increased and usual pressure, regardless of if it occurs with glaucoma, or not; the structure of its activity is connected with a decline in the performance of intraocular fluid. Betaxolol acts after half-an-hour, and the expected result is normally achieved after 2 hours after application.
Xalatan is a chemical analog of the hormone prostaglandin. It is a topical agent available in the form of eye drops with a concentration of latanoprost 50 mcg/ml. Its mode of action is similar to the one of its natural equivalent – the drug increases the flow of intraocular fluid from the hypertensive eyeball. As a result, the pressure in the eyeball slowly decreases. Since this symptom frequently accompanies various eye diseases, Xalatan is often prescribed in combination with other medicines. Today, this drug is among the high-priority agents in the treatment of such an ubiquitous disease as glaucoma.
Prevents the occurrence of epileptic seizures, allodynia and hyperalgesia, and especially the pain response in different models of neuropathic pain. In addition,it reduces the pain response to peripheral inflammation, but does not affect the immediate behavior caused by pain.
Etodolac - has an anti-inflammatory, analgesic, antipyretic effect. The medicine is prescribed in case of rheumatoid arthritis, ankylosing spondylitis, arthrosis with pain syndrome and restriction of movements, acute and chronic osteoarthritis.
Tegretol - anticonvulsant drug, dibenzodiazepine derivative. It also has neurotropic and psychotropic action. Indications for use: epilepsy, alcohol withdrawal syndrome, idiopathic trigeminal neuralgia and trigeminal neuralgia with multiple sclerosis (typical and atypical), idiopathic neuralgia of the glossopharyngeal nerve, diabetic neuropathy with pain syndrome, diabetes insipidus of central genesis,
Cilostazol - reversibly oppresses aggregation of thrombocytes caused by various incentives, surpassing in this respect Аspirin, Dipiridamolum, Тiclopidine and Pentoxifylline. It also inhibits formation of arterial blood clots and proliferation of smooth muscle cells, possesses vasodilating action.
Anti-inflammatory gel for joints and muscles is based on plant components. Rumalaya gel is used for pain in the joints, muscles, relieves swelling and inflammation, makes the joints mobile. The gel is used in the treatment of damaged joints. Unlike tablets, it is used localized, thus gives the best result. The medicine is aimed to treat arthritis, polyarthritis, arthrosis, gout, injuries of the musculoskeletal system, bruises, sprains, rheumatic diseases, osteochondrosis, neuritis, and radiculitis.
Anticholinesterase agent; having a cholinesterase effect through a reversible acetylcholinesterase inhibition and enhancing the action of acetylcholine. Improves neuromuscular transmission, increases the motility of the gastrointestinal tract, increases the tone of urinary bladder, bronchi, the secretion of exocrine glands. Prescribed for myasthenia gravis, postoperative intestinal atony, atonic constipation, bladder atony, post-traumatic movement disorders; flaccid paralysis; residual explication of polio, encephalitis, violation of emptying the bladder after gynecological surgery and childbirth.
Baclofen is a central muscle relaxant. It is assigned if the patient is diagnosed with spasticity in multiple sclerosis, strokes, craniocerebral trauma, meningitis, spinal diseases (infectious, degenerative, tumor and traumatic genesis), with infantile cerebral palsy; alcoholism
Zanaflex (tizanidine) - the drug with an antispastic effect in increased muscle tone, relieves spasms and clonic convulsions.
Assign with painful muscular spasms associated with static and functional spine lesions (cervical and lumbar syndrome), and after surgery for a herniated disc or osteoarthritis of the thigh, as well as for spasms and pain due to multiple sclerosis, chronic myelopathy, degenerative diseases of the spinal cord brain, stroke, with cramps of central origin.
Deltasone - renders an antiinflammatory, antiallergic, antishock and immunodepressive effect. It is taken for treatment of acute and chronic inflammatory diseases of joints, acute asthma, allergic diseases, skin diseases.
Enzymes for inward, affect edema of instigative and non-inflammatory origin (traumatic, sports). Animal studies have shown the anti-inflammatory characteristics of Benzac and mixed enzyme preparations in oral administration. In numerous animal studies, bromelain and trypsin suppressed platelet aggregation. Healthy volunteers who received a combination these substances were not observed to have a violation of the system of the ability of blood to thicken.
Xenical - a powerful, specific and reversible inhibitor of gastrointestinal lipases, which has a long-lasting effect. Its therapeutic effect is carried out in the lumen of the stomach and small intestine and consists in the formation of a covalent bond with the active serine portion of the gastric and pancreatic lipases. The inactivated enzyme at the same time loses the ability to break down food fats coming in the form of triglycerides, to sucking free fatty acids and monoglycerides. Since uncleaved triglycerides are not absorbed, the resulting decrease in the intake of calories into the body leads to a decrease in body weight. Thus, the therapeutic effect of the drug is carried out without absorption into the systemic circulation.
Fluoxetine is an antidepressant group of selective serotonin reuptake inhibitors. It has a timoanaleptic and stimulating effect. It is used for depression of various genesis, obsessive-compulsive disorders, bulimic neuroses.