Pharmacological influence of Calan is explained by braking of a flow of calcium ions through the slowed-down calcic tubules of cellular covers of smooth muscle structure of vessels and a cardiac muscle. Calan is prescribed if it was diagnosed paroxysmal supraventricular tachycardia (except WPW syndrome), sinus tachycardia, premature atrial contraction, blinking and atrial flutter, stenocardia (inc. stress, postinfarction), arterial hypertension, hypertensive crisis, idiopathic hypertrophic subaortic stenosis, hypertrophic cardiomyopathy.
Calan
| Package | pill | Total price | Save | Order |
|---|---|---|---|---|
| 240mg × 30 Pills | $0.86 | $25.87 + Bonus - 4 Pills | - | Add to cart |
| 240mg × 60 Pills | $0.67 | $40.45 + Bonus - 4 Pills | $11.40 | Add to cart |
| 240mg × 90 Pills | $0.61 | $55.03 + Bonus - 7 Pills | $22.50 | Add to cart |
| 240mg × 120 Pills | $0.58 | $69.62 + Bonus - 7 Pills | $33.60 | Add to cart |
| 240mg × 180 Pills | $0.55 | $98.78 + Bonus - 11 Pills | $55.80 | Add to cart |
| 240mg × 270 Pills | $0.53 | $142.53 + Bonus - 11 Pills | $89.10 | Add to cart |
| 240mg × 360 Pills | $0.52 | $186.28 + Bonus - 11 Pills | $122.40 | Add to cart |
| Package | pill | Total price | Save | Order |
|---|---|---|---|---|
| 120mg × 60 Pills | $0.54 | $32.17 + Bonus - 4 Pills | - | Add to cart |
| 120mg × 90 Pills | $0.45 | $40.54 + Bonus - 7 Pills | $8.10 | Add to cart |
| 120mg × 120 Pills | $0.41 | $48.90 + Bonus - 7 Pills | $15.60 | Add to cart |
| 120mg × 180 Pills | $0.36 | $65.63 + Bonus - 11 Pills | $32.40 | Add to cart |
| 120mg × 270 Pills | $0.34 | $90.73 + Bonus - 11 Pills | $54.00 | Add to cart |
| 120mg × 360 Pills | $0.32 | $115.82 + Bonus - 11 Pills | $79.20 | Add to cart |
| Package | pill | Total price | Save | Order |
|---|---|---|---|---|
| 80mg × 90 Pills | $0.31 | $27.47 + Bonus - 7 Pills | - | Add to cart |
| 80mg × 180 Pills | $0.27 | $48.34 + Bonus - 11 Pills | $7.20 | Add to cart |
| 80mg × 270 Pills | $0.26 | $69.22 + Bonus - 11 Pills | $13.50 | Add to cart |
| 80mg × 360 Pills | $0.25 | $90.10 + Bonus - 11 Pills | $21.60 | Add to cart |
| Package | pill | Total price | Save | Order |
|---|---|---|---|---|
| 40mg × 60 Pills | $0.43 | $25.93 + Bonus - 4 Pills | - | Add to cart |
| 40mg × 120 Pills | $0.35 | $41.48 + Bonus - 7 Pills | $9.60 | Add to cart |
| 40mg × 240 Pills | $0.30 | $72.59 + Bonus - 11 Pills | $31.20 | Add to cart |
| 40mg × 300 Pills | $0.29 | $88.15 + Bonus - 11 Pills | $42.00 | Add to cart |
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Calan Product Description
Drug Uses
Calan is a calcium channel blocker, which expands coronary arteries and coronary arterioles that supply blood and oxygen to the heart. The drug reduces the total peripheral vascular resistance and myocardial oxygen demand.
Calan has antianginal, antiarrhythmic and hypotensive action, so it is used to treat:
- hypertension (essential hypertension)
- tachyarrhythmia (atrial fibrillation, atrial flutter)
- angina (chronic stable angina, angina at rest, vasospastic angina)
The dosage regimen and duration of antihypertensive therapy are set individually considering the disease severity, the patient's condition and the treatment efficiency.
Typically, the treatment is started with a daily dose of Calan 240 mg divided into 3 doses. If necessary, the daily dose of the antihypertensive drug can be gradually increased to Calan 480 mg. The maximum daily dose should not exceed 480mg.
Antihypertensive effect of Calan develops in about 1.5 hours after the intake and lasts about 10 hours. Sustained therapeutic effect of Calan is usually reached during the first week of the systematic use of these tablets.
Missed dose
For sustained antihypertensive effect, patients should follow a prescribed dosage regimen of Calan and not miss the tablets of this antihypertensive drug. If the patient forgets to take the therapeutic dose of the drug, he or she should take it as soon as possible. However, if the interval between the last Calan tablet and the missed one is about 3 hours, the patient should skip the missed dose. The next tablet of Calan should be taken according to the dose schedule.
More Information
Calan tablets are taken during or immediately after eating swallowing whole and using plenty of fluids. Antihypertensive drug should be used with caution in patients with hepatic insufficiency and in elderly patients, since Calan can be slowly excreted from the body in such patients.
Calan use is not recommended during pregnancy. Due to the high risk of side effects in infants, nursing mothers should also renounce the use of Calan tablets.
Storage
Calan modified-release tablets are recommended to be stored in a tight package away from light, at room temperature below 25°C. Throw away Calan at the term indicated on the label.
Calan Safety Information
Warnings
Clinical studies have shown that Calan can affect the pharmacological efficiency of other antiarrhythmic medications (such as, flecainide, disopyramide). Co-administration of these drugs can cause a negative inotropic effect and disrupt atrioventricular conduction.
During antihypertensive therapy, patients are advised to avoid using alcohol, since Calan may increase alcohol concentration in the blood and develop side effects.
In simultaneous use of Calan with neuromuscular blocking drugs, it should be noted that the antihypertensive drug is able to increase the activity of the last ones. Therefore, dose reduction of one of the medications can be required.
Some patients taking Calan together with Telithromycin (semisynthetic antibacterial agent) may develop bradyarrhythmias and hypotension. In simultaneous prescription of Rifampicin with Calan, the dose adjustment of the last one can be required, since Rifampicin is able to lower the hypotensive effect of Calan.
Disclaimer
Information on the treatment of arrhythmia, angina and hypertension published in Calan review is provided for informational purposes only and should not be construed as a substitute for consultation with a cardiologist or treating physician. The online pharmacy disclaims all liability in respect to actions taken or not taken based on any or all the information provided in the Calan tablets review.
Calan Side Effects
While using the recommended (optimal) doses of Calan, adverse effects are rare and usually mild and transient. Clinical studies have shown that the most common adverse effects associated with Calan tablets are constipation (7%), nausea (3%) and dizziness (3%). During Calan clinical trials, less than 4% of patients were forced to abandon this antihypertensive agent because of heart failure and hypotension. In Calan overdose, the risk of severe adverse effects that require the withdrawal of this drug increases.
Ventolin is a medicament for eliminating asthma attacks (bronchial) and other reversible diseases with bronchial obstruction.
The main active substance is salbutamol.
Geodon - antipsychotic medicine (neuroleptic). It is taken at treatment of schizophrenia and similar mental disorders (treatment and prevention of aggravations), stopping of psychomotor excitement at patients with schizophrenia.
Endep - tricyclic antidepressant. The mechanism of antidepressive action is connected with increase in concentration of noradrenaline in synapses and/or serotonin in CNS (decrease in return absorption). Accumulation of these neurotransmitters results from inhibition of their return capture by membranes of presynaptic neurons.
An antidepressant from the group of selective inhibitors of serotonin reverse capture. It has thymoanaleptic and stimulating effect. Improves the mood, reduces tension, anxiety and fear, eliminates dysphoria. Doesn’t cause sedation. When taken in high therapeutic doses, it virtually doesn’t effect the function of cardiovascular and other systems.
Actos, which is pioglitazone - is prescribed to patients with diabetes of type 2 (both as monotherapy, and in a form of the combined therapy with sulphonylurea, metformin or insulin as additional medicine to dietotherapy and physical exercises). Pioglitazone represents peroral hypoglycemic medicine of Thiazolidinediones alignment which effect depends on insulin presence. It is a high-selective agonist of gamma receptors, activated by proliferator of peroxysom (PPAR-γ).
Augmentin - the Antibiotic of a broad spectrum of activity. It has bacterolytic (destroying bacteria) effect. It is active concerning a wide range of aerobic and anaerobic gram-positive and aerobic gramnegative microorganisms, including strains producing betalactamase. It is prescribed at diagnosing of bacterial infections caused by microorganisms, sensitive to drug: infections of upper respiratory tracts, bacterial infections of skin and soft tissues, infections of urogenital tract, sepsis, infection pelvic organs.
Ciplox is a medicine which is antimicrobial of the fluoroquinolone group. The system of action is connected with exposure to DNA bacteria. The medicine eliminates microorganisms that are both at rest and reproduction. A range of action of the drug includes such types of negative and positive microorganisms: Shigella, Salmonella, Citrobacter, Klebsiella, Enterobacter, Serratia, Hafnia, Edwardsiella and others. It is resistant to Ureaplasma uralyticum, Nocardia asteroids, Treponema pallidum. Such defiance to the drug develops slowly and gradually.
Floxin - antimicrobic broad-spectrum agent from group of fluroquinolone. It is active concerning the microorganisms producing beta lactamelements and fast-growing atypical mycobacteria. It is taken at respiratory infection, the ENT organs, skin, soft tissues, bones, joints, abdominal cavity, urinary tract.
Flagyl - antiprotozoan and antimicrobic drug. It is prescribed at treatment of protozoan inspections (abenteric amebiasis, including amoebic abscess of liver, an intestinal amebiasis, trichomoniasis, giardiasis, balanthidiasis, lambliasis, skin leushmaniosis, mecotic vaginitis, mecotic urethritis), pseudomembranous colitis, gastritises, ulcer, prevention of postoperative complications (especially interventions at segmented intestine, perirectal area, appendectomy, gynecologic operations).
Cefixime is a medicine intended for the treatment of acute and chronic bronchitis, bacterial bronchitis, middle ear inflammation, pharyngitis and tonsillitis, bacterial infections of the urinary tract, cystitis, urethritis, pyelonephritis, cerivitis.
Suprax - is a semisynthetic antibiotic of the group of the third generation cephalosporins for oral administration. It has bactericidal action. The drug is formed on the basis of cefiximum under the name Suprax given by such companies:Wyeth, Elder Pharmaceuticals, Fujisawa, Gedeon Richter, Hikma Pharmaceuticals, Lederle, Lupin Pharmaceuticals, Sanofi-Aventis.
Stromectol - a medical preparation that effectively cope with many kinds of parasites. It is used to treat lice, scabies, as well as onchocerciasis (river blindness) and other nematodes in humans and animals. It is applied externally and internally, depending on the disease.
Avalide is an effective medicine which aim is to lower the blood pressure. Hypertension provokes serious diseases as strokes, heart attack, and problems with the kidney. An angiotensin receptor blocker and diuretic are the basic components of the drug. The first one relaxes the walls of the blood vessels letting the blood move freely without the pressure. The second component stimulates urination so that a patient can get rid of extra salt and water which also provoke high blood pressure.
"Loop" diuretic, used for edematous syndrome with CHF II-III st., liver cirrhosis, kidney disease; swelling of the lungs or brain; arterial hypertension, hypercalcemia. Causes a rapidly advancing, strong and short-term diuresis. Has natriuretic and chlororetic effects, increases the excretion of K +, Ca2 +, Mg2 +.
Exforge the combined antihypertensive which includes amlodipine and valastran. Valsartan - a specific blocker of AT1 receptors of angiotensin II. Amlodipin - calcium channel blocking agents of III generation, inhibits transmembrane receipt of Ca2+ in cardiomyocytes and smooth muscle cells of vessels, by weakening them.
A thiazide diuretic of the average intensity, applied in arterial hypertension, edema syndrome of different origin, gestosis and diabetes insipidus. Reduces reabsorption of Na+ at the level of the Henle loop cortical segment, without affecting its segment lying in the medulla of the kidney that detects a weaker diuretic effect compared with furosemide.
A selective calcium channel blockers; a derivative of dihydropyridine; has a vasodilating, antihypertensive, antianginal effect. Has a high selective activity against smooth muscle of the arterioles. Prescribed to the patients with hypertension, angina pectoris (voltage, vasospastic, unstable with the ineffectiveness of beta-blockers and nitrates), Raynaud's syndrome (as a symptomatic drug).
Caverta - another affordable version of Indian Viagra created by Ranbaxy, released as Caverta 100mg and Caverta 50mg.
Levitra - the main component - the active agent Vardenafil which promotes strengthening of blood circulation in generative organs of men. It allows to reach a high level erection at sexual stimulation, and also to increase sensitivity of head of a penis and to make sexual intercourse longer and more pleasant. The main feature of a drug Levitra - quickness of effect, duration of impact on an organism up to 12 hours and a very small number of side effects.
Aciphex - the medicine, normalizing acidity of a stomach, inhibitor of a proton pomp. It is prescribed at gastroduodenal ulcer in the exacerbation phase, gastroesophageal reflux disease; states which are characterized by pathological hyper secretion including Zollinger-Ellison syndrome. In combination with bactericide - Helicobacter pylori eradication at patients with gastric ulcer or chronic gastritis; treatment and prevention of recurrence of an ulcer at patients with gastric ulcer related to Helicobacter pylori.
A symptomatic medication against vomiting and nausea of various origins. Used at vomiting caused by radiation therapy or cytotoxic drugs intake, hypotony and atony of the stomach and intestines, biliary dyskinesia, reflux esophagitis, flatulence, aggravation of gastric ulcer and duodenal gut, when performing contrast studies of the gastrointestinal tract. It reduces the moving activity of the esophagus, increases the tone of the lower esophageal sphincter, accelerates gastric emptying, and accelerates the movement of food through the small intestine without causing diarrhea. Stimulates the secretion of prolactin.
Fights diarrhea (acute and chronic of various genesis: allergic, emotional, drug, radiation, with a change in diet and quality of food, in violation of metabolism and absorption), used for regulation of stool in patients with ileostomy. Loperamide (the effective ingredient of Imodium) reduces the tone and motility of the smooth muscles of the intestine. Slows down the peristalsis and increases the transit time of intestinal contents. Increases the tone of the anal sphincter, promotes retention of fecal masses and reduced urge to defecate. The effect develops quickly and lasts for 4-6 hours.
Levaquin is used to treat infections of the lower respiratory tract, urinary tract, kidneys, skin, soft tissues, chronic bronchitis, acute sinusitis, chronic bacterial prostatitis and tuberculosis. The drug is a fluoroquinolone, a broad-spectrum antimicrobial bactericide. It blocks DNA gyrase and topoisomerase IV, disrupts supercoiling and cross-linking of DNA gaps, suppresses DNA synthesis, causes profound morphological changes in the cytoplasm, cell wall and bacterial membranes.
An antiarrhythmic Ia class drug, a blocker of the "fast" Na+ channels. It has a membrane stabilizing, anti-arrhythmic, hypotensive and m-anticholinergic action. In normally functioning sinus node it causes acceleration of the sinus rhythm due to the antimuscarinic effect.
The drug dilates coronary vessels (mostly arterioles) and causes a significant increase in volumetric blood flow velocity. Increases the content of oxygen in venous blood of coronary sinus and its absorption by myocardium. Promotes the development of collateral coronary circulation, reduction in a systemic vascular resistance, improves microcirculation, has angioprotective action.
Strattera - the drug with an international non-proprietary name of the active substance - Atomoxetine, it is intended as a sympathomimetic agent for the prevention and treatment of attention deficit hyperactivity disorder (ADHD) in children 6 years of age and older, adolescents and adults.
Zerit - treatment of infection caused by HIV, with severe clinical manifestations and ineffectiveness or intolerance of zidovudine, and other antiretroviral drugs. The nucleoside analogue of thymidine is phosphorylated by cellular enzymes to its active form - stavudine triphosphate. Suppresses reverse transcriptase of HIV, cellular DNA polymerases (beta and gamma), inhibits the synthesis of viral and mitochondrial DNA. It is active against HIV-1.
Flexeril - medicine acting against muscular spasms. It possesses sedative action, it is not recommended to be engaged in potentially dangerous types of activity if a person takes Flexeril. As well as in a case with narcotic analgetics, Flexeril is not recommended to take longer than seven days as in case of a long taking there can be a dependence.
Proscar - the drug is used to treat men’s baldness and benign prostatic hyperplasia. Inhibits the 5-alpha-reductase which converts testosterone into a more active 5-alpha-dihydrotestosterone, reduces its concentration in blood and prostate tissue.
Actonel, which is risedronate - is prescribed for treatment and prevention of osteoporosis (post-menopausal, caused by corticosteroids), Paget disease. Risedronate binds to substance of a bone tissue, inhibits its resorption mediated by osteoclasts and reduces a bone turn (does not break process of formation of a bone). It increases the biomechanical strength and volume of bone mass. The maximum decrease in a bone turn is observed in 3-6 months, remaining at the same level during a course of treatment.
An antimicrobial agent from the fluoroquinolone group. It has a broad spectrum of antibacterial action. The therapeutical indications include bacterial infection of the urinary tract (pyelonephritis, cystitis, urethritis), genitals (prostatitis, cervicitis, endometritis), gastrointestinal tract (salmonellosis, shigellosis), uncomplicated gonorrhea. Also used to prevent infections in patients with granulocytopenia, diarrhea of travelers.
Synthroid finds use as a hormone-regulating agent for managing low levels of triiodothyronine/thyroxine. It also has a pronounced therapeutic effect on goiters of certain types. Synthroid often accompanies surgeries and other medical means of treating thyroid cancer. The drug compensates for the insufficient production of thyroid hormones by standing in their place as a synthetic substitution. Compensations of this kind help the patient’s body to restitute the normal rate of metabolism. Synthroid also helps to fight obesity due to its ability to remove the initial thyroid gland-related causes as such.
Urispas is an oral antispasmodic drug approved to prevent bladder spasms caused by urethral catheterization, infectious and /or inflammatory diseases of the urogenital system or neurological disorders.
Anti-migraine drug. Specific and selective agonist of 5-HT1-serotonin receptors, localized predominantly in the blood vessels of the brain and it does not affect other subtypes of 5-HT-serotonin receptors (5-HT2-7). Causes narrowing of the vessels of the carotid arterial bed, that supply extracranial and intracranial tissues with blood (vasodilation of the meninges and / or their edema is the main mechanism of migraine development in humans) without significantly affecting cerebral blood flow.
An anti-migraine drug. Used for emergency treatment to eliminate migraine, with aura as well. A selective agonist of 5-hydroxytryptamine 1D receptors. The effect can be observed within 30 minutes after the intake.
Rizact -pills swallowed for the urgent care of the headache phase within the attacks of migraines. This Cipla product is a great painkillerthanks to an action of Rizatriptan, which is characterized by an analgesic effect.
Dapsone antibacterial agent, which is active concerning Mycobacterium leprae and tuberculosis. It has bacteriostatic action similar to antagonists of p-aminobenzoic acid.
The effect of clomipramine is to inhibit the opposite neurological catching of serotonin and noradrenaline. The most crucial is the suppression of serotonin recapture. In addition, the medicine has a broad range of other pharmacological actions: alpha 1-adrenoliticheskoe, anticholinergic, antigestagen and antiserotonergic. The pill acts on the depressive disorder in general. The difference is usually observed after 2-3 weeks of therapy. Acticine also has a specific influence on obsessive-compulsive disorders.
Differin is a white gel or cream. The drug is used to treat acne. It can also be used to combat comedones. Differin monotherapy is helpful in case of minor acne. For the treatment of severe and moderate degree of acne, the drug is used in conjunction with systemic drugs (antiandrogens, antibacterial agents). The drug is well tolerated. It rarely causes irritation, so its use is good even for those who have sensitive skin with acne. The gel is more suitable for oily skin and the cream suits better for dry skin.