A selective calcium channel blockers; a derivative of dihydropyridine; has a vasodilating, antihypertensive, antianginal effect. Has a high selective activity against smooth muscle of the arterioles. Prescribed to the patients with hypertension, angina pectoris (voltage, vasospastic, unstable with the ineffectiveness of beta-blockers and nitrates), Raynaud's syndrome (as a symptomatic drug).
Plendil
| Package | pill | Total price | Save | Order |
|---|---|---|---|---|
| 10mg × 30 Pills | $1.06 | $31.67 + Bonus - 4 Pills | - | Add to cart |
| 10mg × 60 Pills | $0.85 | $50.90 + Bonus - 4 Pills | $12.60 | Add to cart |
| 10mg × 90 Pills | $0.78 | $70.13 + Bonus - 7 Pills | $25.20 | Add to cart |
| 10mg × 120 Pills | $0.74 | $89.36 + Bonus - 7 Pills | $38.40 | Add to cart |
| 10mg × 180 Pills | $0.71 | $127.83 + Bonus - 11 Pills | $63.00 | Add to cart |
| 10mg × 270 Pills | $0.69 | $185.51 + Bonus - 11 Pills | $99.90 | Add to cart |
| 10mg × 360 Pills | $0.68 | $243.21 + Bonus - 11 Pills Free Trackable Delivery | $136.80 | Add to cart |
| Package | pill | Total price | Save | Order |
|---|---|---|---|---|
| 5mg × 30 Pills | $0.87 | $26.06 + Bonus - 4 Pills | - | Add to cart |
| 5mg × 60 Pills | $0.70 | $42.17 + Bonus - 4 Pills | $10.20 | Add to cart |
| 5mg × 90 Pills | $0.65 | $58.28 + Bonus - 7 Pills | $19.80 | Add to cart |
| 5mg × 120 Pills | $0.62 | $74.39 + Bonus - 7 Pills | $30.00 | Add to cart |
| 5mg × 180 Pills | $0.59 | $106.61 + Bonus - 11 Pills | $50.40 | Add to cart |
| 5mg × 270 Pills | $0.57 | $154.95 + Bonus - 11 Pills | $81.00 | Add to cart |
| 5mg × 360 Pills | $0.56 | $203.27 + Bonus - 11 Pills Free Trackable Delivery | $111.60 | Add to cart |
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Plendil Product Description
Drug Uses
Plendil is a calcium channel blocker, used to treat hypertension (high blood pressure). Antihypertensive drug Plendil relaxes the blood vessels, thus increasing the blood flow and lowwering the blood pressure.
Because Plendil has no effect on the venous smooth muscle, the antihypertensive drug does not cause orthostatic hypotension (colloquially as head rush).
Calcium channel blocker Plendil is prescribed to adults and elderly patients for treatment of hypertension and prophylaxis of chronic stable angina pectoris. To treat high blood pressure, an initial recommended Plendil dose is 5 mg per day.
Depending on the tolerability and the effect, the daily dose of Plendil can be increased up to 10mg or decreased to 2.5mg. If necessary, therapy with Plendil can be supported with another antihypertensive agent. The recommended maintenance Plendil dose is 5-10mg per day.
Missed dose
If more than 12 hours has passed after a missed dose of Plendil, do not take the calcium antagonist. In this case just return to the regular dosing schedule of Plendil.
More Information
Plendil is completely absorbed from the gastrointestinal tract and immediately provides an antihypertensive effect, which lasts about 2-5 hours. At the systematic application of antihypertensive agent Plendil, substantial control of blood pressure lasts for 24 hours. Plendil is well tolerated by the patients with renal transplant and requires no modification of the recommended dosage in patients with renal impairment.
Storage
Antihypertensive Plendil agent should be stored in a dark place in a tightly closed container, at room temperature not exceeding 25°C.
Plendil Safety Information
Warnings
Plendil is recommended to be indicated with caution to the hypertensive patients with heart failure. Coadministration of the calcium channel blocker with beta-adrenergic blocking agents is especially recommended to be avoided.
In some cases, the hypertension treatment in the patients with coronary artery disease may cause significant hypotension and result in myocardial ischaemia. Therefore, the level of blood pressure is recommended to be thoroughly monitored in these patients during the antihypertensive therapy with Plendil. Also the patients with a history of cerebrovascular insufficiency should be careful and try to avoid hypotension.
Disclaimer
This review of Plendil contains only general information on the hypertension treatment. This information in no case should be treated as medical advice from the cardiologist or other professional healthcare provider. The online pharmacy shall not be liable for any loss or damage, caused due to improper use of the information provided on antihypertensive agent Plendil.
Plendil Side Effects
Adverse effects after the application of Plendil are usually transient and decrease when dosages are decreased. Only about 6% of patients taking Plendil, have to discontinue the treatment due to blushing, ankle edema and headache. Other common and the most serious adverse effects after the use of Plendil are: nausea, dizziness, vomiting, weakness, palpitation, flush, gingival overgrowth, paraesthesia, low blood pressure, costiveness or paresthesia.
Augmentin - the Antibiotic of a broad spectrum of activity. It has bacterolytic (destroying bacteria) effect. It is active concerning a wide range of aerobic and anaerobic gram-positive and aerobic gramnegative microorganisms, including strains producing betalactamase. It is prescribed at diagnosing of bacterial infections caused by microorganisms, sensitive to drug: infections of upper respiratory tracts, bacterial infections of skin and soft tissues, infections of urogenital tract, sepsis, infection pelvic organs.
Sumycin - An antibiotic based on tetracycline, a brand of such pharmaceutical companies as Bristol-Myers Squibb, Apothecon, Par Pharmaceutical.
Cefixime is a medicine intended for the treatment of acute and chronic bronchitis, bacterial bronchitis, middle ear inflammation, pharyngitis and tonsillitis, bacterial infections of the urinary tract, cystitis, urethritis, pyelonephritis, cerivitis.
A thiazide diuretic of the average intensity, applied in arterial hypertension, edema syndrome of different origin, gestosis and diabetes insipidus. Reduces reabsorption of Na+ at the level of the Henle loop cortical segment, without affecting its segment lying in the medulla of the kidney that detects a weaker diuretic effect compared with furosemide.
Aceon, which is perindopril - is prescribed at hypertensia, stroke prevention, chronic cardiac failure. Medicine has a vasorelaxant action, it reduces an afterload due to TPR relief, the medicine reduces resistance in vessels of lungs. It is observed increase of the minute volume of myocardium and increase tolerance of myocardium to strain. The medicine has the natriuretic effect and cardioprotection action. The effect of hypotension is observed in 60 minutes after taking the medicine. Arterial pressure loss isn't followed by development of tachycardia. The maximum therapeutic effect is observed in 4-8 hours, the effect is long-term (up to 24 hours). Perindopril improves brain, kidneys, and myocardium circulation, it reduces the needs of cardiomyocytes for oxygen at CHD.
The component of Duphalac is Lactulose. It is used as a means to decrease the content of hydrogen nitride in the blood. It is a disaccharide that is not captivated in the digestive tract. Under the action of microorganisms of the colon, the component is cleaved to form organic acids, together with acetic and lactic acids. The effect of acids on the mucous membrane of the colon increases motility. The number of proteolytic bacteria is reduced with the growth in the number of acidophilic Increasing the acidity of the environment slows down the absorption of NH3 from the intestine. It was found that Duphalac facilitates the circulation of ammonia from the vessels into the cavity of the colon.
Anti-migraine drug. Specific and selective agonist of 5-HT1-serotonin receptors, localized predominantly in the blood vessels of the brain and it does not affect other subtypes of 5-HT-serotonin receptors (5-HT2-7). Causes narrowing of the vessels of the carotid arterial bed, that supply extracranial and intracranial tissues with blood (vasodilation of the meninges and / or their edema is the main mechanism of migraine development in humans) without significantly affecting cerebral blood flow.
The drug is used for treatment of infectious diseases such as community acquired pneumonia, exacerbation of chronic bronchitis, acute sinusitis, pharyngitis and skin infections. The active ingredient in Omnicef is cefdinir—a semi-synthetic cephalosporin broad-spectrum antibiotic of the third generation for oral administration. Like other cephalosporin antibiotics, cefdinir has a bactericidal action against susceptible organisms through the inhibition of synthesis of bacteria peptidoglycan cell walls by interfering with the final stage of transamination, required for cross-linking.