Celebrex - non-steroidal anti-inflammatory drug. It has antiinflammatory, febrifugal and analgesic effect, slows down aggregation of thrombocytes. Oppressing COX-2, reduces quantity of Pg (preferentialy in the inflammation center), suppresses exudative and proliferative phases of inflammation. At prescribtion in high doses, prolonged use or specific features of an organism the selectivity decreases.
Celebrex
| Package | pill | Total price | Save | Order |
|---|---|---|---|---|
| 200mg × 30 Pills | $0.99 | $29.74 + Bonus - 4 Pills | - | Add to cart |
| 200mg × 60 Pills | $0.72 | $43.25 + Bonus - 4 Pills | $16.20 | Add to cart |
| 200mg × 90 Pills | $0.63 | $56.77 + Bonus - 7 Pills | $32.40 | Add to cart |
| 200mg × 120 Pills | $0.59 | $70.29 + Bonus - 7 Pills | $48.00 | Add to cart |
| 200mg × 180 Pills | $0.54 | $97.32 + Bonus - 11 Pills | $81.00 | Add to cart |
| 200mg × 270 Pills | $0.51 | $137.87 + Bonus - 11 Pills | $129.60 | Add to cart |
| 200mg × 360 Pills | $0.50 | $178.42 + Bonus - 11 Pills | $176.40 | Add to cart |
| Package | pill | Total price | Save | Order |
|---|---|---|---|---|
| 100mg × 30 Pills | $0.80 | $23.98 + Bonus - 4 Pills | - | Add to cart |
| 100mg × 60 Pills | $0.58 | $34.88 + Bonus - 4 Pills | $13.20 | Add to cart |
| 100mg × 90 Pills | $0.51 | $45.79 + Bonus - 7 Pills | $26.10 | Add to cart |
| 100mg × 120 Pills | $0.47 | $56.69 + Bonus - 7 Pills | $39.60 | Add to cart |
| 100mg × 180 Pills | $0.44 | $78.48 + Bonus - 11 Pills | $64.80 | Add to cart |
| 100mg × 270 Pills | $0.41 | $111.19 + Bonus - 11 Pills | $105.30 | Add to cart |
| 100mg × 360 Pills | $0.40 | $143.89 + Bonus - 11 Pills | $144.00 | Add to cart |
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Celebrex Product Description
Drug Uses
Celebrex is a nonsteroidal anti-inflammatory agent used for the symptomatic treatment of inflammatory joint diseases (IJD), as well as for pain relief of various intensity and localization. Celebrex effectively relieves pain and joint inflammation in patients with:
- degenerative rheumatic diseases (including osteoarthritis);
- juvenile rheumatoid arthritis (including systemic, polyarticular and pauciarticular types);
- autoimmune rheumatic diseases (including rheumatoid arthritis, and ankylosing spondylitis).
For relief of the symptoms of rheumatic diseases in children younger than two years and adults, the maintenance doses of Celebrex vary from 100mg to 200mg per day. For the management of severe rheumatoid arthritis flare-ups, the maximum daily dose of Celebrex 400mg can be prescribed.
Due to the fact that Celebrex capsules exert not only anti-inflammatory, but also a powerful analgesic effect, they can be used to relieve acute pain caused by:
- tooth extraction;
- trauma and sprains;
- orthopedic surgery.
Women can use Celebrex capsules for management of acute pain episodes caused by primary dysmenorrhea. To treat pain syndromes in adult men and women, the maximum daily dose of Celebrex is 400mg divided into two equal doses.
Missed Dose
If you use Celebrex on a schedule and forgot to take a regular dose, take the missed dose of this anti-inflammatory drug as soon as you remember. If it is almost time for the next dose of Celebrex, skip the missed dose of this drug and continue your regular dosing schedule.
More Information
- If Celebrex capsules are used as an analgesic agent, the duration of their use should not exceed 7 days in a row.
- The duration of Celebrex use for the symptomatic treatment of rheumatic diseases is prescribed individually for each patient.
- Patients with chronic rheumatic conditions may require a symptomatic treatment of joint disease lasting from several months to several years.
Storage
Celebrex capsules should be stored at room temperature of up to 25°C. Storage and transportation of Celebrex capsules may be at temperature of up to 30°C. This anti-inflammatory / analgesic agent should be kept out of sight and reach of children and pets.
Celebrex Safety Information
Warnings
In prolonged use of Celebrex and while using high doses of this drug, a risk of gastrointestinal bleeding, hypertension, cardiovascular and cerebrovascular events may increase. Smoking, alcohol use, elderly age, and Celebrex combination with other drugs are potential factors for increasing the risk of serious gastrointestinal and / or cardiovascular effects.
Disclaimer
The information contained in this Celebrex review is published for informational purposes only and not intended as a substitute for services provided by a rheumatologist, gynecologist, surgeon or other medical professionals. The online pharmacy is not liable for any damage of a material or immaterial nature ensuing from the use or non-use of information about the analgesic / anti-inflammatory therapy provided in Celebrex review.
Celebrex Side Effects
During clinical trials of Celebrex capsules, it was noted that elderly people aged 75 and older experienced unwanted effects more frequently than patients of other age groups did. However, regardless of the patient’s age and the used Celebrex dose, this anti-inflammatory drug rarely causes serious unwanted effects. Celebrex may increase the risk of hypertension, sinusitis, dizziness, pharyngitis, flatulence, diarrhea, rhinitis, rash or peripheral edema in some patients.
The most common reasons for Celebrex cancellation because of unwanted effects are abdominal pain and dyspepsia. These unwanted effects do not occur or are mild in the majority of patients with rheumatic diseases.
Glucophage - guanyl guanidine, hypoglycemic medicine for peroral takein. At patients with a diabetes mellitus reduces concentration of glucose in blood by oppression of gluconeogenesis in a liver, reduction of absorption of glucose from GIT and increase of its utilization in tissues. Stabilizes or reduces a body weight.
Zetia contains ezetrol as an active ingredient, which is a selective representative of a new class of lipid-lowering drugs that reduce the absorption of cholesterol in the intestine, including cholesterol from plant fats.
Methocarbamol – a muscle relaxant used to treat muscle spasms and pain. Its action is to block pain nerve impulses sent to the brain. The mechanism of action is not completely clear. The drug has no direct effect on skeletal muscles. It's likely that its effect is associated with sedative properties.
Trecator SC - an anti-TB drug (antituberculous), contains Ethionamide as a basic substance, the drug is prescribed for the treatment of multidrug-resistant type of tuberculosis, with the mycobacterium tuberculosis susceptible to it.
Aggrenox - the combined antiplatelet agent. There are two active ingredients - acetilsalicylic acid and dipiridamol. Action of such combination is caused by different biochemical mechanisms. Aggrenox is prescribed for secondary prevention of ischemic stroke which proceeds as thrombosis. Medicine is also effective for prevention of transitory ischaemic attack.
Olanzapine is an antipsychotic drug (neuroleptic). It is shown in schizophrenia in adults, psychotic disorders, bipolar affective disorder in adults, depressive states.
Combined oral contraceptives block the action of gonadotropins. The first effect of these drugs is aimed to inhibit ovulation. The drug leads to modifications in cervical mucus. Thus, it is strenuous for sperm to pass to the uterine cavity and affect the uterine lining, thereby reducing the possibility of implementation. It helps to prevent pregnancy. Moreover, oral contraceptives prevent pregnancy and have a number of advantages. They have an impact on the cycle of menses and it becomes regular. The amount of blood loss at the time of menstruation is shorter as well as the loss of iron, dysmenorrhea is rare.
Uroxatral - Alfuzosinis an active substance, as an antagonist of the α1 adenogenetic receptor, this drug relaxes the muscles of the prostate and the bladder. Used in the treatment of benign prostatic hyperplasia (BPH). Reduces pressure in the urethra and reduces resistance to urine flow, eases urination and eliminates dysuria.
Coumadin is a drug that promotes blood thinning in the veins. Within a short period of application, anticoagulant reduces viscous blood consistency and lowers the risk of blood clots. The drug is prescribed only after laboratory blood tests when certain symptoms are detected. Independent use of tablets is prohibited, only a doctor may establish the need for taking the drug. Thrombosis is a disease that is characterized by the formation of blood clots. In case of delayed treatment, this disease may cause disorders of oxygen metabolism in the blood and embolism.
It is used for the treatment of spasticity in multiple sclerosis, strokes, TBI, meningitis, spinal diseases (infectious, degenerative, tumor and traumatic genesis), in children's cerebral palsy; alcoholism (affective disorders). Reducing the excitability of the end sections of the afferent sensitive fibers and suppressing the intermediate neurons, inhibits the mono- and polysynaptic transmission of nerve impulses; reduces the preliminary stress of the muscle spindles.
Enzymes for inward, affect edema of instigative and non-inflammatory origin (traumatic, sports). Animal studies have shown the anti-inflammatory characteristics of Benzac and mixed enzyme preparations in oral administration. In numerous animal studies, bromelain and trypsin suppressed platelet aggregation. Healthy volunteers who received a combination these substances were not observed to have a violation of the system of the ability of blood to thicken.