Erythromycin is a macrolide antibiotic of bacteriostatic action. In high concentrations and relatively high-sensitivity microorganisms may have a bactericidal effect.
Erythromycin
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Product Description
According to the spectrum of antimicrobial action erythromycin is an antibiotic, close to penicillins. It is active against gram-positive and gram-negative microorganisms. It also acts on a number of gram-positive bacteria, like brucella, rickettsia, causative agents of trachoma and syphilis. It has little or no effect on most gram-negative bacteria, mycobacteria, small and medium viruses, fungi. Erythromycin is tolerated by patients better than singingillines, and can be used by those who is allergic to penicillins.
Safety information
Erythromycin is indicated:
as a treatment of pneumonia, pneumoplethritis, bronchiectatic disease on the acute stage and other infectious diseases of the lungs caused by antibiotic-sensitive microorganisms;
in case of septic conditions, erysipelas, mastitis, osteomyelitis, peritonitis, purulent otitis and other purulent inflammatory processes;
it is also prescribed for patients with syphilis and with intolerance to antibiotics of the penicillin group;
locally, as a treatment for pustular lesions of the skin, infected wounds, bedsores, etc., as well as conjunctivitis, blepharitis, trachoma.
Erythromycin is not prescribed in case of meningitis, as it does not penetrate through the blood-brain barrier.
Mode of application
Prior to the appointment of a patient to the drug, it is desirable to determine the sensitivity to it of the microflora that caused the exact disease in patient. For oral administration, erythromycin is prescribed in the form of tablets or capsules. A single dose for an adult is 0.25 g, in case of serious diseases - 0.5 g. It is taken every 4 - 6 hours, an hour or hour and a half before meals. The maximum single dose for adults is 0.5 g orally, and daily - 2 g. Children under 14 years take 20-40 mg per 1 kg of their weight, children over 14 years - take the same dose as adults.
Contraindications
The drug is contraindicated to patients with individual hypersensitivity to it and with severe failure of liver function. The drug should be administered with caution by patients who use to have any type of allergic reaction.
Side effects
The likelihood of side effects during the treatment by erythromycin are relatively rare, still among reported reactions there are nausea, vomiting, diarrhea. In case of prolonged usage, there may be disorder of the liver function (jaundice). In some cases, there may occur an increased sensitivity to the drug accompanied by allergic reactions. In case of prolonged treatment by erythromycin, some microorganisms may become resistant to the drug.
Aristocort - glucocorticoid drug (the adrenal hormone influencing carbohydrate and protein metabolism). Renders prominent antiinflammatory, antiallergic and immunodepressive (suppressing immunity - body defences of an organism) effect. It is prescribed at rheumatism, allergic reactions, multiform erythema (variously proceeding skin disease which occurs with rubefaction of affected area of skin), pseudorheumatism (the infectious and allergic disease from a group of collagenoses which is characterized by chronic progressing inflammation of joints); systemic lupus erythematosus and other collagenoses.
Tenorminis a cardioselective beta-adrenoblocker. It is based on a substance called Atenolol, which blocks nerve impulses, which leads to a decrease in the frequency and strength of the heartbeat. Atenolol has antihypertensive (lowers pressure), antianginal (eliminates the symptoms of myocardial ischemia) and antiarrhythmic (eliminates heart rhythm disturbances) by action.
Xenical - a powerful, specific and reversible inhibitor of gastrointestinal lipases, which has a long-lasting effect. Its therapeutic effect is carried out in the lumen of the stomach and small intestine and consists in the formation of a covalent bond with the active serine portion of the gastric and pancreatic lipases. The inactivated enzyme at the same time loses the ability to break down food fats coming in the form of triglycerides, to sucking free fatty acids and monoglycerides. Since uncleaved triglycerides are not absorbed, the resulting decrease in the intake of calories into the body leads to a decrease in body weight. Thus, the therapeutic effect of the drug is carried out without absorption into the systemic circulation.
The drug made of herbs is used in the treatment of varicose veins, thrombophlebitis, hemorrhoids, proctitis. Its active components reduce varicose veins and prevent their formation. In general, it has a healing effect on veins, improves blood circulation, strengthens the walls of venous vessels, relieves inflammation and swelling, reduces pressure in the venous system of the liver. Pilex has an anti-inflammatory effect on the nodes of the venous system, accelerates blood stagnation, lowers cholesterol, relieves discomfort, itching and pain as well as inflammation of the rectum, hemorrhoids.