The drug is an inhibitor of the enzyme peptidyl. It inhibits the angiotensin-converting enzyme, which catalyzes the conversion of angiotensin I to vasoconstrictor peptide angiotensin II. Angiotensin II also stimulates the secretion of aldosterone by the adrenal cortex. Inhibition of ACE leads to reduced concentrations of angiotensin II, resulting in low aldosterone secretion. The decrease in the latter leads to an increase in the content of potassium in the blood serum. Since the mechanism is believed to be based on the inhibition of the renin-angiotensin-aldosterone system, it reduces blood pressure even in patients with hypertension with low renin levels.
Lopid
| Package | pill | Total price | Save | Order |
|---|---|---|---|---|
| 300mg × 30 Pills | $1.64 | $49.15 + Bonus - 4 Pills | - | Add to cart |
| 300mg × 60 Pills | $1.20 | $72.04 + Bonus - 4 Pills | $26.40 | Add to cart |
| 300mg × 90 Pills | $1.05 | $94.92 + Bonus - 7 Pills | $53.10 | Add to cart |
| 300mg × 120 Pills | $0.98 | $117.80 + Bonus - 7 Pills | $79.20 | Add to cart |
| 300mg × 180 Pills | $0.91 | $163.56 + Bonus - 11 Pills | $131.40 | Add to cart |
| 300mg × 270 Pills | $0.86 | $232.20 + Bonus - 11 Pills Free Trackable Delivery | $210.60 | Add to cart |
| 300mg × 360 Pills | $0.84 | $300.84 + Bonus - 11 Pills Free Trackable Delivery | $288.00 | Add to cart |
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The tablets are aimed at normalizing blood plasma composition. They reduce triglyceride content and increase apolipoprotein AI. The medicine inhibits peripheral lipolysis, helps to remove free fatty acids from the liver and blocks the inclusion of acyl in synthesized triglycerides. They lower its levels in the liver.
Product Description
The pills make faster turnover and removal of cholesterol and promote its excretion from the body. The components of the remedy are well absorbed if you take it inside. Absorption occurs one and a half hours after administration. The tablets are low-toxic and they make a concentration of lipids in the blood lower. They decrease lipoprotein in patients with hypertriglyceridemia and increase the number of triglycerides in the blood.
The drug does not react to the treatment by diet or other hypolipidemic agents. It increases the concentration of HDL (high-density lipoproteins).The medicine is prescribed for patients with hypertriglyceridemia if they are resistant to a therapeutic diet or other related means. If one has hyperchylomicronemia (increased blood levels of chylomicrons /neutral fat particles with a diameter of 1 micron due to family deficiency of lipoprotein lipase (an enzyme that destroys lipoproteins), the drug will be ineffective.
Safety Information
It is necessary to check the number of lipids in the blood during the treatment. If the effectiveness of the drugs is not manifested within three months, then the therapy should be stopped. It is also necessary to follow the diet. In long-term care one needs a constant control of the peripheral blood and as well as of indications of the functions of the liver. If there are significant changes in the liver, it is necessary to stop treatment until the normal findings.
If you miss a dose of pills you need to take the next one as soon as possible and double it twice. Sometimes the pain in the muscles may appear and in this case, it is necessary to exclude the presence of myositis. If it is found in the body, the treatment will be canceled. One should stop taking pills if cholelithiasis is detected. The tablets are incompatible with lovastatin because there may be a severe form of myopathy or liver failure. The drug enhances the effect of indirect anticoagulants and oral hypoglycemic drugs.
While taking the drugs, the risk of violations of fat metabolism increases. Adult patients have prescribed pills of 0.45 grams twice a day. It is usually taken in the morning 30 minutes before breakfast or in the evening and 30 minutes before dinner. The highest therapeutic effect is observed after three or four weeks after the first administration of the tablet.
Side Effects
The medicine has an adverse reaction on the nervous system. One may feel the following symptoms:
- dizziness;
- a headache;
- excessive fatigue;
- drowsiness;
- depression.
Sometimes there is dysfunction in the digestive system, such as dry mouth, low appetite, nausea, vomiting, heartburn, constipation or diarrhea. On the part of the human motor system can there are:
- Myasthenia gravis;
- Myalgia;
- Arthralgia;
- Rhabdomyolysis.
In the genitourinary system, there are decreases in potency and libido. Sometimes there are allergic reactions that appear in the skin, for example, rash or dermatitis. Among other sideway actions, one can identify visual impairment, hypokalemia, alopecia, synovitis.
Erythromycin is a macrolide antibiotic of bacteriostatic action. In high concentrations and relatively high-sensitivity microorganisms may have a bactericidal effect.
Zithromax - antibiotic of a wide spectrum of action. Antibiotic-azalide, a representative of a new subgroup of macrolide antibiotics. In the focus of inflammation it has a bactericidal effect. For the active ingredient of Zithromax, Azithromycin, all the gram-positive cocci (except those bacteria which are resistant to erythromycin) are susceptible.
Topamax - the remedy with an active ingredient: topiramate, it is used as a monotherapy for the treatment of adults and children 6 years of age with partial attacks with or without secondary generalized seizures and primary generalized tonic-clonic seizures; as an adjunct therapy for the treatment of adults and children 2 years of age with partial attacks with or without secondary generalized seizures or primary generalized tonic-clonic seizures and the treatment of attacks associated with Lennox-Gasto syndrome; to prevent migraine attacks in adults, after careful evaluation of alternative treatment options. Topiramate is not recommended for the treatment of acute conditions.
Casodex - racemic mix, a nonsteroid anti-androgen which does not influence endocrine system in any way. The mechanism of effect of active component consists in its ability to contact androgenic receptors of "wild type" and to oppress the activity, thereby, bringing a prostate tumor into a regression stage. Casodex is taken as a medicine for monotherapy, and as a part of complex treatment (radiation).
Betahistine is diaminoxidase inhibitor - the enzyme inactivating histamine. Stabilizing the histamine which is formed in an organism, betahistine has a histamine-like effect. Drug is effective at peroral taking (by mouth). Drug expands precapillary sphincters of vessels of an inner ear, it improves microcirculation. The main use of betahistine has at Menyer's disease and similar diseases which are followed by dizziness attacks, a sonitus, a hearing impairment, nausea, vomiting.