Trazodone is an antidepressant, a thiazolopyridine derivative. It also has a timoleptic, anxiolytic, sedative and miorelaxing action. Has a high affinity for some subtypes of serotonin receptors, inhibits the reuptake of serotonin; The neuronal capture of norepinephrine and dopamine affects little.
Trazodone
| Package | pill | Total price | Save | Order |
|---|---|---|---|---|
| 100mg × 30 Pills | $0.78 | $23.50 + Bonus - 4 Pills | - | Add to cart |
| 100mg × 60 Pills | $0.65 | $38.79 + Bonus - 4 Pills | $7.80 | Add to cart |
| 100mg × 90 Pills | $0.60 | $54.09 + Bonus - 7 Pills | $16.20 | Add to cart |
| 100mg × 120 Pills | $0.58 | $69.38 + Bonus - 7 Pills | $24.00 | Add to cart |
| 100mg × 180 Pills | $0.56 | $99.98 + Bonus - 11 Pills | $39.60 | Add to cart |
| 100mg × 270 Pills | $0.54 | $145.87 + Bonus - 11 Pills | $64.80 | Add to cart |
| 100mg × 360 Pills | $0.53 | $191.75 + Bonus - 11 Pills | $90.00 | Add to cart |
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Product Description
Trazodone is an antidepressant, which has a timoleptic, that is, mood-enhancing action, simultaneously combined with an anxiolytic and tranquilizing (anti-anxiety and soothing) effect. Applied with different forms of depression (suppressed states / endogenous, psychotic, neurotic, somatogenic, etc.), proceeding with anxiety, tension. Due to the good tolerability and lack of anticholinergic action, trazodone is widely used in the treatment of elderly patients with organic diseases of the central nervous system, as well as in the complex treatment of patients with somatic diseases (internal diseases) complicated by mental disorders (anxiety, tension, etc.).
Safety information
The initial dose for ingestion is 50 mg 3 times a day, then depending on the type and severity of depression may be increased up to 300-500 mg per day. Therapeutic effect is usually observed within 3-7 days from the beginning of treatment.
The drug should not be administered simultaneously with MAO inhibitors.
Trazodone is not indicated for pregnant women.
In case of the treatment by Trazodone the breastfeeding period should be stopped. Trazodone and its metabolites are found in the milk of lactating rats. It is not known whether trazodone is secreted into human milk in human milk.
Side effects
- fatigue, weakness, headache, dizziness, insomnia, drowsiness, agitation, psychosis, hypomania, hallucinations, tremor, muscle twitches, large convulsive seizures (grand mal), aphasia, ataxia, akathisia, dyskinesia, paresthesia, confusion, syncopal conditions , blurred vision, diplopia;
- arterial hypotension, incl. Orthostatic; Atrial fibrillation, arrhythmias, congestive heart failure, leukocytosis or leukopenia, neutropenia, hemolytic anemia, methemoglobinemia;
- increased appetite, dryness and unpleasant taste in the mouth, hypersalivation, caries, diseases of the peri-toothed tissues, candidiasis of the oral cavity, nausea, vomiting, flatulence, diarrhea, constipation, cholestasis, increased bilirubin and amylase in the blood plasma, jaundice;
- urinary retention, increased urination, hematuria, premature menstruation, hirsutism, increased libido, priapism, impotence, retrograde ejaculation;
- skin rash, hives;
- myalgia, pain in the chest, alopecia, psoriasis, swelling.
An antifungal agent from the group of imidazole derivatives for external and local applications reduces the synthesis of ergosterol, which is a part of the cell membrane of the microbial wall and leads to a change in its structure and properties. In fungicidal concentrations, it interacts with mitochondrial and peroxidase enzymes, leading to an increase in the concentration of hydrogen peroxide to toxic levels, which also contributes to the destruction of fungal cells. The pills are active against pathogenic dermatophytes, pathogens of multi-colored lichen, erythrasma, gram-positive and gram-negative bacteria.
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Tricor - is a hypolipidemic agent, has an uricosuric and antiplatelet effect. In combination with diet therapy, the drug is prescribed for a long-term treatment, the effectiveness of which must be periodically checked by determining serum lipid levels.
Premature ejaculation (PE) is a distressing male sexual dysfunction that can be present from the first sexual encounter or can develop later in life. Men with premature ejaculation appear to go through the same process of ejaculation as other men, but it happens more quickly and with a reduced feeling of control.
Vastarel - the main substance of the drug is trimetazidine, which is used for the prevention of angina attacks in IHD, as well as in vertigo caused by violations of cerebral circulation, Meniere's disease, noise in the ears. It is believed that the beneficial effect of trimetazidine in myocardial ischemia is mainly associated with its antioxidant and antihypoxic properties and cytoprotective effects on the function of cardiomyocytes.
Bystolic is an anti-anginal, antihypertensive anti-arrhythmic drug. It stimulates the internal surface of the blood vessels (endothelium) for the production of nitric oxide, which also helps the vessels to relax. It is used for hypertension, IHD, Stenocardia tension.
Xalatan is a chemical analog of the hormone prostaglandin. It is a topical agent available in the form of eye drops with a concentration of latanoprost 50 mcg/ml. Its mode of action is similar to the one of its natural equivalent – the drug increases the flow of intraocular fluid from the hypertensive eyeball. As a result, the pressure in the eyeball slowly decreases. Since this symptom frequently accompanies various eye diseases, Xalatan is often prescribed in combination with other medicines. Today, this drug is among the high-priority agents in the treatment of such an ubiquitous disease as glaucoma.
Etodolac - has an anti-inflammatory, analgesic, antipyretic effect. The medicine is prescribed in case of rheumatoid arthritis, ankylosing spondylitis, arthrosis with pain syndrome and restriction of movements, acute and chronic osteoarthritis.
