Sustiva is an antiviral agent. A non-nucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1 (HIV-1). It is based on efavirenz and is named like Sustiva by Bristol-Myers Squibb and United Drug.
Sustiva
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Sustiva (Efavirenz) product description
Sustiva is a drug belonging to the group of non-nucleoside reverse transcriptase inhibitors. It is widely used in order to cure the HIV infection. Introduced in 1998, Efavirenz being combined with two reverse transcriptase suppressor showed greater efficacy than protease inhibitors and nevirapine. The studies that were conducted in inSouth Africa among 2817 HIV-positive adult patients demonstrated the benefits of efavirenz before nevirapine. Sustiva as a whole has proved to be a more effective and safe drug. Sustiva is able to inhibit the advancement of HIV up to 144 weeks. The advantages of Sustiva include the fact that it can be taken 1 time per day. Studies have shown that in 95% of patients 48 weeks after the onset of Sustiva, there was a decrease in viral load and an increase in CD4 T-lymphocyte count. This medical remedy has good tolerability. At the beginning of the therapy, there are adverse reactions on the CNS, but after a few weeks, their severity can be significantly reduced. The advised dosage of Efavirenz is 600 mg once a day (tablets can be as per 200 or 600 mg). It is desirable to take the dose before a bedtime.
Sustiva safety information
Sustiva is not prescribed to pregnant, because it has teratogenic properties. During the medical care, it is necessary to choose an adequate way of contraception. Against the background of Sustiva, there was a significant reduction in the contraceptive effect of the use of implants with etonogestrel. This medical agent helps to lower the concentrations of etonogestrel, levonorgestrel, and norelgestromin in the blood.
Do not administrateSustiva concomitantly with astemizole or ergot alkaloids, cisapride or midazolam, as well as with terfenadine, and triazolam, or even with oral contraceptives. The simultaneous consumption of saquinavir and amprenavir with efavirenz is possible if this combination enhances ritonavir (otherwise serum concentrations are inadequate). It is not recommended to eat efavirenz together with food containing a large amount of fat. As this affects the absorption of the drug, lowering its concentration. If the medical care with efavirenz was preceded by the treatment with protease inhibitors, it is advised that, during the first week of the regiment, efavirenz continues to receive a protease suppressor. When using lopinavir, reinforced atazanavir, indinavir, rifabutin, methadone simultaneously with efavirenz, the adjustment of the dosages of these drugs is required.
Sustiva side effects
The administration of Sustiva is most often accompanied by adverse effects on the CNS. Often there are undesirable effects such as the nightmares, the feeling of dizziness, drowsiness, feeling of confusion, the incoherence of mind, impaired concentration, insomnia, depersonalization. The patient before the administration of efavirenz should remember that he or she would rather not engage in potentially hazardous motions that may need one to be better concentrated than usual. In particular, during the regiment of treatment with a help of Sustiva, it is not allowed to drive the car or operate any machinery.
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Co-Amoxiclav - co-formulated antibacterial agent, combine of bactericidal antibiotic of a broad spectrum of activity, from a group of semi-synthetic penicillin - Amoxicillin and Betalactamase inhibitor.
Allopurinol - a drug that promotes the excretion of uric acid and the removal of urinary calculi.
Advair Diskus is a drug manufactured to cope with diseases which attack bronchi and lungs. Medics prescribe it for people with COPD, pant, wheeze, dyspnea, pulmonary emphysema, and chronic bronchitis. It consists of two main components: a corticosteroid (Fluticasone) and a long-acting beta agonist (Salmeterol). The first component reduces the irritation and the swelling of lungs and bronchi. The second component makes the breathing easier. Doctors prescribe the drug for patients who need a combination treatment when one medication doesn’t work. The medicine is a part of a long-term medication as it isn’t effective in case of sudden asthma attacks.
Claritin prevents development and facilitates the course of allergic reactions. Possesses antiallergic, antipruritic, antiexudative action. Reduces permeability of capillaries, controls oedemata of tissues, removes spasms of smooth muscles. It is prescribed at allergic rhinitis, conjunctivitis, pollinosis, urticaria fever, angioedema, pruritic dermatosis; pseudo-allergic reactions, caused by release of histamine; allergic reactions at stings of insects.
Clarinex is an antihistamine, anti-allergic, anti-inflammatory drug in the form of tablets. Selectively blocks peripheral histamine H1 receptors. It is used for symptomatic therapy of seasonal and all-year-round allergic rhinitis, chronic idiopathic urticaria.
The medicine is blue or white tablets, the dose of the active substance is 75, 100 and 150 mg. Tablets have the bitter taste and a slight anesthetic effect on the oral mucosa. Pills may be quickly dissolved in water. Bupron is a second-generation antidepressant. Its effectiveness as an anti-nicotine drug is based on the suppression of psychological dependence on nicotine (nicotine dependence), as well as on the direct antidepressant effect, which reduces the negative manifestations that appear when a person gives up smoking.
Anafranil, which is clomipramine - is a tricyclic antidepressant. Clomipramine has antiserotonin effect, it eliminates night enuresis, causes loss of appetite. Sedative action is shown due to linkng with H1-histamine receptors, blocking of alpha-adrenoceptors. Medicine eliminates arrhythmia, slows down ventricular conductivity. The anti-depressive effect is implemented due to increase in concentration of noradrenaline, serotonin in synapses because of weakening of the process of recapture of these substances by presynaptic neurons.
Sinequan - antidepressant, which is taken as prescribed by the doctor in case of the following indications: depression, anxiety and sleep disturbance in neuroses, alcoholism, organic diseases of the central nervous system, psychoneurotic disorders with anxiety, depression, psychotic depression (including the involutionary, reactive depressive phase of manic-depressive Psychosis). In general therapeutic practice - duodenal ulcer, dumping syndrome, premenstrual syndrome, chronic pain in cancer patients, skin itching, chronic idiopathic urticaria.
Januvia - is a drug for adult patients with type 2 diabetes mellitus, in order to control the glycemic level under conditions of monotherapy as part of combined treatment regimens. The drug is prescribed to patients with ineffectiveness of diet therapy in combination with optimal physical activity, with the impossible use of metformin because of its intolerance.
Glucotrol peroral hypoglycemic medicine. It is taken at a diabetes mellitus of type 2 (at inefficiency of dietotherapy). It has pancreatic and extra pancreatic effects. Stimulates secretion of insulin by reductions of the threshold of irritation with glucose of beta cells of pancreas, increases sensitivity to insulin and extent of its linkng with target cells, increases insulin release, strengthens influence of insulin on glucose absorption by muscles and liver, brakes lipolysis in fatty tissue.
Fulvicin - the antifungal antibiotic, which is taken at mycosis of skin, hair and nails (favus, trichophytosis, microsporia of a pilar part of the head, microsporia of smooth skin, dermatomycosis of beard and moustaches, epidermophitia of smooth skin, inguinal epidermophitia, onychomycoses). It is effective concerning fungus of the sort Trichophyton, Microsporum, Epydermophyton, Achorionum; causes disturbance of the structure of a mitotic spindle and synthesis of a cell wall at chitin fungus, suppresses division of fungal cells in metaphase and synthesis of protein because of disruption of linking with template-RNA.
Diflucan - antifungal medicine, possesses highly specific action, inhibiting activity of enzymes of fungus. It is taken at systemic lesions caused by fungus including meningitis, sepsis, infections of lungs and skin as at patients with a normal immune response, and at patients with various forms of immunosuppression.
An antifungal agent from the group of imidazole derivatives for external and local applications reduces the synthesis of ergosterol, which is a part of the cell membrane of the microbial wall and leads to a change in its structure and properties. In fungicidal concentrations, it interacts with mitochondrial and peroxidase enzymes, leading to an increase in the concentration of hydrogen peroxide to toxic levels, which also contributes to the destruction of fungal cells. The pills are active against pathogenic dermatophytes, pathogens of multi-colored lichen, erythrasma, gram-positive and gram-negative bacteria.
Famvir - antiviral medicine which is taken for prevention and treatment of herpes at primary infection, post-herpetic neuralgia, recurrent genital herpes. Pro-medicine; represents a 6-deoxysidiacetil analog of active antiviral agent of a penciclovir.
Teramycin acts depressingly on pathogens of many diseases, as well as biomycin. It is less toxic and longer preserves its action in the body. The medicine is used for the treatment of anthrax, teileriosis, cholera and pasteurellosis and other diseases.
Hyzaar - complex hypertensia medicine. A hydrochlorothiazide - Thiazide diuretic of average force and losartan - hypotensive drug which is specific blocker angiotensin II (AT1 type) of receptors. Does not suppress a kinase II - enzyme destroying bradykinin.
A tricyclic antidepressant with a relatively short latency period. It has almost no sedative effect. therapeutical indications include: depressive phases of a manic-depressive psychosis, all other forms of endogenous depression (reactive and neurotic). In combination with amitriptyline it is used for depressions that occurred during treatment with reserpine. In combination with neuroleptics, it is used in the treatment of depression that developed during treatment of schizophrenic psychoses.
The drug is an inhibitor of the enzyme peptidyl. It inhibits the angiotensin-converting enzyme, which catalyzes the conversion of angiotensin I to vasoconstrictor peptide angiotensin II. Angiotensin II also stimulates the secretion of aldosterone by the adrenal cortex. Inhibition of ACE leads to reduced concentrations of angiotensin II, resulting in low aldosterone secretion. The decrease in the latter leads to an increase in the content of potassium in the blood serum. Since the mechanism is believed to be based on the inhibition of the renin-angiotensin-aldosterone system, it reduces blood pressure even in patients with hypertension with low renin levels.
Avana - generic of Stendra, based on avanafil, whose mission is aimed at fighting impotence. It differs from the usual Viagra with minimal contraindications, longer positive outcome and the prompt onset of action. Taking one pill,the outcome begins to be felt after fifteen minutes and lasts six hours.
The medicine is used for the temporary correction of male erectile disorders. It represents the last generation of drugs for men, as it was developed less than 10 years ago and has the most modern composition than the previous tablets for treating of potency.Avanafil is an active substance of the drug.In the process of excitation in the cavernous body of the male sexual organ,, it relaxes the arteries and vessels to increase blood flow in the right places. The enzyme FDE-5 in some cases disrupts the natural process, not allowing accumulating cGMP to the required level.
Super Kamagra - Ajanta product combining two active substances: sildenafil, with a dosage of 100 mg, and dapoxetine, with a dosage of 60 mg. Such a successful mix of these elements helps men who have some potency disorders to fix 2 difficulties at once: 1 - connected with an erection, another - with premature ejaculation.
Viagra Plus is the latest form of the medical treatment which is known worldwide. The formula is intensified by active medicinal plants, causing a boundless feeling of potentiality, unlimited desire and infinite lasting. The ginseng is one of the main ingredients of Viagra Plus, which carries out stimulation and increases endocrine activity in an organism, strengthens metabolism and facilitates cordial activity, helping thereby an arterial flow of blood, stimulating think-tanks and is promoted also by simplification of functioning of the central nervous system. Erection, sexual desire, success of sexual intercourse are guaranteed. From 400 mg of Viagra Plus - 50 mg make sildenafit, the remained 350 mg are ginseng and vitamins.
Viagra Professional - Advantage of Professional Viagra from usual Viagra is that it works twice longer (6 - 8 hours) and has a stronger effect. Strengthens desire, improves brightness of sexual feelings and increases duration of sexual intercourse.
Viagra Super Active - an innovative formula of drug for treatment of erectile dysfunction. Drug is produced in gelatin capsules that allows to avoid emergence of heartburn or other unpleasant feelings in a stomach. Sildenafil Super Active also has a number of advantages. It is soaked quicker and works longer. The principle of action is identical with ordinary Sildenafil. Each capsule contains about 100 mg of active ingredient. That is quite enough for any man.
Suhagra If one has difficulties with a masculine power, we’d suggest buying Suhagra® a drug of an Indian enterprise, named Cipla, founded back in 1937. It is an exact Viagra® copy, a well-known worldwide medical mean targeted to eliminate the ED problems. Still, Suhagra® is not a Generic Drug. It is a completely independent brand pharmaceutical product that has been verified by all needed health organizations in developed countries. One can buy Suhagra® in 180 countries around the globe. This is an evidence of the reliability and safety of the good.
Zantac - ranitidin - the drug is intended for the treatment of duodenal ulcers, benign gastric ulcer, postoperative ulcer, reflux esophagitis, Zollinger-Ellison syndrome, epigastric or chest pain. The administration of ranitidine is indicated in cases where a decrease in gastric secretion and a decrease in the production of hydrochloric acid is desirable, for the prevention of gastrointestinal bleeding, for the prevention of recurrence of bleeding in patients with bleeding ulcers of the stomach and duodenum, before general anesthesia in patients with a presumed risk of aspiration of acidic stomach contents (Mendelssohn syndrome), especially in women during childbirth delivery clashes.
Florinef is a brand name of Fludrocortisone. It is a corticosteroid produced to treat adrenogenital syndrome (also called Apera-Galle syndrome), Addison's disease, orthostatic hypotension, cerebral salt wasting syndrome, and adrenal insufficiency. The drug replenishes the deficiency of hormones of the adrenal cortex. 1 tablet contains 0.1 mg of fludrocortisone acetate. It participates in the metabolism, including mineral and carbohydrate one. The drug causes the retention of sodium ions and promotes the excretion of potassium.
An antimicrobial bactericide - synthetic derivative of nitroimidazole. Used in urethritis, vaginitis, intestinal amoebiasis, liver amoebiasis, giardiasis.
Methocarbamol – a muscle relaxant used to treat muscle spasms and pain. Its action is to block pain nerve impulses sent to the brain. The mechanism of action is not completely clear. The drug has no direct effect on skeletal muscles. It's likely that its effect is associated with sedative properties.
Topamax - the remedy with an active ingredient: topiramate, it is used as a monotherapy for the treatment of adults and children 6 years of age with partial attacks with or without secondary generalized seizures and primary generalized tonic-clonic seizures; as an adjunct therapy for the treatment of adults and children 2 years of age with partial attacks with or without secondary generalized seizures or primary generalized tonic-clonic seizures and the treatment of attacks associated with Lennox-Gasto syndrome; to prevent migraine attacks in adults, after careful evaluation of alternative treatment options. Topiramate is not recommended for the treatment of acute conditions.
Olanzapine is an antipsychotic drug (neuroleptic). It is shown in schizophrenia in adults, psychotic disorders, bipolar affective disorder in adults, depressive states.
Enalapril is an angiotensin converting enzyme inhibitor (or ACE inhibitor); administered in hypertensive pediatric patients (from 1 month old and above), adults and elderly patients for treatment
An antispasmodic drug, which removes pain and reduces the tone of smooth muscles: gastrointestinal tract, biliary tract, uterus, it also relaxes the detrusor (direct antispasmodic and m-anticholinergic effect). Increases bladder capacity, reduces the frequency of detrusor contractions, hinders urination. Well tolerated when appointed for a long term. Used in neurogenic bladder (including detrusor hyperreflexia, multiple sclerosis or spina bifida), urinary incontinence (of idiopathic origin), nocturnal enuresis (in children older than 5 years).
Rogaine is the brand recommended by trichologists all over the world for hair restoration. For more than 20 years, the medicine has shown excellent results, which are confirmed in more than 2000 clinical trials. Using Rogaine 5 one is able to grow new hair and stop further hair loss. The lotion has no smell and is easy to use. The medicine is a great discovery that stops baldness and regains self-confidence. Rogaine lotion Extra Strength 5% Minoxidil stimulates the growth of new healthy hair. The first signs of growth appear after 2-3 months of regular use of the drug.
Propecia - an anti-hormonal drug. Used to reduce the size of the prostate gland, to increase the maximum speed of urine outflow, reducing the risk of developing acute urinary retention. The drug also turned out to be effective in the treatment of men’s alopecia.
Finpecia - potent pharmaceutical agent aimed to cure an illness named alopecia, of an androgenic as well as a hereditary genesis. Moreover, it stops the manifestation of various maladies deteriorating the advancement of the follicles and other difficulties connected with baldness.
Atorlip-10 belongs to the drugs which reduce the level of low-density lipoprotein and triglycerides. Doctors identify the level with the help of blood tests. If the level is rather high, then the patients are prescribed the pills. Heart attack, strokes, high blood pressure, diabetes, and other cardiovascular diseases can be prevented thanks to the medicine. The pills are effective in case the disease is acquired due to the improper way of living or when it’s inherited.
Diabecon is aimed at increasing peripheral glucose intake, restoring B cells, increasing C – peptide levels. Diabecon has antioxidant properties, protecting cells from oxidative stress. The drug eliminates the painful symptoms of diabetes: polyuria, fever, burning feet and hands. Symptoms are eliminated not immediately after administration but within two to three weeks. This is due to changes in chemical processes in the body that cause symptoms of the disease. Diabecon naturally reduces craving for sweets, restores the patient's appetite, normalizes the functions of liver and kidney.
Casodex - racemic mix, a nonsteroid anti-androgen which does not influence endocrine system in any way. The mechanism of effect of active component consists in its ability to contact androgenic receptors of "wild type" and to oppress the activity, thereby, bringing a prostate tumor into a regression stage. Casodex is taken as a medicine for monotherapy, and as a part of complex treatment (radiation).
Doxazosin is used for treating hypertension (high blood pressure) and enlarged prostate. The drug increases the blood flow by expanding the veins and arteries. It also relaxes the muscles of the prostate and the neck of urinary bladder, making it easier to urinate.
Haldol antipsychotic remedy, butyrophenone derivative. It has a powerful antipsychotic effect, moderate sedation. The mechanism of antipsychotic action of haloperidol is associated with the blockade of dopamine receptors in the mesocortex and limbic system.
The medicine is a cardioselective blocker of beta-1-adrenergic receptors. A major risk index for glaucomatous scotoma is an increased tension. When its rate is soaring, the eyes are more damaged. As a consequence, a visual field narrows. Betoptic reduces both increased and usual pressure, regardless of if it occurs with glaucoma, or not; the structure of its activity is connected with a decline in the performance of intraocular fluid. Betaxolol acts after half-an-hour, and the expected result is normally achieved after 2 hours after application.
Prevents the occurrence of epileptic seizures, allodynia and hyperalgesia, and especially the pain response in different models of neuropathic pain. In addition,it reduces the pain response to peripheral inflammation, but does not affect the immediate behavior caused by pain.
Azulfidine - a medicine with antimicrobic and antiinflammatory properties. It is taken at ulcer colitis, an ulcer proctitis, a pseudorheumatism, Crohn's disease. After reception Sulfasalazinum - it is observed the normal intestinal microflora, and as result of the molecule of active ingredient breaks up to compound components: sulphapyridine and 5-aminosalicylic acid. These substances have antibacterial and antiinflammatory activity. Antiinflammatory effect of 5-aminosalicylic acid thanks to low ability to absorption is defined generally in walls of a large intestine. Sulphapyridine has generally systemic antiinflammatory effect due to better absorption.
Tegretol - anticonvulsant drug, dibenzodiazepine derivative. It also has neurotropic and psychotropic action. Indications for use: epilepsy, alcohol withdrawal syndrome, idiopathic trigeminal neuralgia and trigeminal neuralgia with multiple sclerosis (typical and atypical), idiopathic neuralgia of the glossopharyngeal nerve, diabetic neuropathy with pain syndrome, diabetes insipidus of central genesis,
Cilostazol - reversibly oppresses aggregation of thrombocytes caused by various incentives, surpassing in this respect Аspirin, Dipiridamolum, Тiclopidine and Pentoxifylline. It also inhibits formation of arterial blood clots and proliferation of smooth muscle cells, possesses vasodilating action.
Anti-inflammatory gel for joints and muscles is based on plant components. Rumalaya gel is used for pain in the joints, muscles, relieves swelling and inflammation, makes the joints mobile. The gel is used in the treatment of damaged joints. Unlike tablets, it is used localized, thus gives the best result. The medicine is aimed to treat arthritis, polyarthritis, arthrosis, gout, injuries of the musculoskeletal system, bruises, sprains, rheumatic diseases, osteochondrosis, neuritis, and radiculitis.
Anticholinesterase agent; having a cholinesterase effect through a reversible acetylcholinesterase inhibition and enhancing the action of acetylcholine. Improves neuromuscular transmission, increases the motility of the gastrointestinal tract, increases the tone of urinary bladder, bronchi, the secretion of exocrine glands. Prescribed for myasthenia gravis, postoperative intestinal atony, atonic constipation, bladder atony, post-traumatic movement disorders; flaccid paralysis; residual explication of polio, encephalitis, violation of emptying the bladder after gynecological surgery and childbirth.
Zanaflex (tizanidine) - the drug with an antispastic effect in increased muscle tone, relieves spasms and clonic convulsions.
Assign with painful muscular spasms associated with static and functional spine lesions (cervical and lumbar syndrome), and after surgery for a herniated disc or osteoarthritis of the thigh, as well as for spasms and pain due to multiple sclerosis, chronic myelopathy, degenerative diseases of the spinal cord brain, stroke, with cramps of central origin.
Enzymes for inward, affect edema of instigative and non-inflammatory origin (traumatic, sports). Animal studies have shown the anti-inflammatory characteristics of Benzac and mixed enzyme preparations in oral administration. In numerous animal studies, bromelain and trypsin suppressed platelet aggregation. Healthy volunteers who received a combination these substances were not observed to have a violation of the system of the ability of blood to thicken.
Fosamax - drug for treatment of Paget disease, osteoporosis at women in a postmenopause, osteoporosis at men, a hypercalcemia at malignant tumors. Active alendronate ingredient - non-hormonal specific inhibitor of an osteoclastic bone resorption, suppresses osteoclasts. Taking of Fosamax stimulates bone formation, recovers positive balance between a resorption and recovery of a bone, progressively increases the mineral density of bones, promotes formation of a normal bone tissue with normal histologic structure.
The drug made of herbs is used in the treatment of varicose veins, thrombophlebitis, hemorrhoids, proctitis. Its active components reduce varicose veins and prevent their formation. In general, it has a healing effect on veins, improves blood circulation, strengthens the walls of venous vessels, relieves inflammation and swelling, reduces pressure in the venous system of the liver. Pilex has an anti-inflammatory effect on the nodes of the venous system, accelerates blood stagnation, lowers cholesterol, relieves discomfort, itching and pain as well as inflammation of the rectum, hemorrhoids.
Fluoxetine is an antidepressant group of selective serotonin reuptake inhibitors. It has a timoanaleptic and stimulating effect. It is used for depression of various genesis, obsessive-compulsive disorders, bulimic neuroses.