Arava - a basic medicine with antirheumatic effect. Action is happened due to active metabolite of leflunomid. It has the inhibiting action on degidrorotate-dehydrogenase. Taking the medicine the progression of rheumatoid arthritis is slowed down, it is stopped the affection of arthral layers. Development of therapeutic effect is observed in a month. Increase of effect is noted within half a year.
Arava
| Package | pill | Total price | Save | Order |
|---|---|---|---|---|
| 20mg × 30 Pills | $2.33 | $69.75 + Bonus - 4 Pills | - | Add to cart |
| 20mg × 60 Pills | $1.89 | $113.60 + Bonus - 4 Pills | $26.40 | Add to cart |
| 20mg × 90 Pills | $1.75 | $157.45 + Bonus - 7 Pills | $52.20 | Add to cart |
| 20mg × 120 Pills | $1.68 | $201.30 + Bonus - 7 Pills Free Trackable Delivery | $78.00 | Add to cart |
| 20mg × 180 Pills | $1.61 | $289.01 + Bonus - 11 Pills Free Trackable Delivery | $129.60 | Add to cart |
| 20mg × 270 Pills | $1.56 | $420.56 + Bonus - 11 Pills Free Trackable Delivery | $207.90 | Add to cart |
| Package | pill | Total price | Save | Order |
|---|---|---|---|---|
| 10mg × 30 Pills | $1.34 | $40.34 + Bonus - 4 Pills | - | Add to cart |
| 10mg × 60 Pills | $1.04 | $62.53 + Bonus - 4 Pills | $18.00 | Add to cart |
| 10mg × 90 Pills | $0.94 | $84.71 + Bonus - 7 Pills | $36.00 | Add to cart |
Your order will be packed safely and securely and dispatched within 24 hours. This is exactly how your parcel will look like (pictures of a real shipping item). It has the size and the look of a regular private letter (9.4x4.3x0.3 inches or 24x11x0.7cm), and it does not disclose its contents
Arava product description
Drug uses
Arava is a pyrimidine synthesis inhibitor, used to treat symptoms of rheumatoid arthritis. The drug is characterized by anti-inflammatory, immunosuppressive and antiproliferative action, slowing progressive joint destruction in active rheumatoid arthritis.
Arava tablets are prescribed to adolescents above 18-year-old, adults and elderly patients for the treatment of:
- active psoriatic arthritis
- active rheumatoid arthritis
Treatment is usually recommended to begin with a single Arava dose of 100mg per day to be taken for three consecutive days. In therapy of rheumatoid arthritis and psoriatic arthritis, the maintaining dose of Arava is advised as 20mg per day.
Arava doses above 20mg /day are not recommended. In case of poor drug tolerability, the daily dose can be reduced to 10mg. Arava administration in elderly patients above 65 years does not require dosage adjustment. Typically, the therapeutic effect of Arava is observed in 4-5 weeks and can be further accumulated for up to 4-6 months.
Missed dose
If the patient has forgotten to take an Arava pill, it should be taken as soon as possible, unless it is not the time for the next dose of the drug. In case if it is the nearly time to take the next Arava pill, a missed dose is recommended to be skipped, and a succeeding dose to be taken as usual. Patients should not double-up on the next dose, otherwise allergic reactions or side effects may appear.
More information
Arava tablets are prescribed to be swallowed whole with plenty of water. The drug can be taken regardless of food, at the same time every day. During treatment, the patients are recommended to refrain from alcoholic beverages. Arava pills together with alcohol can adversely affect the patient’s liver state.
Storage
Pyrimidine synthesis inhibitor Arava should be stored at room temperature below 25°C in the original package to avoid moisture and light on pills. Do not store Arava in facilities like bathroom or kitchen, or accessible to children.
Arava safety information
Warnings
Arava is not recommended for pregnant women and breastfeeding mothers. The drug may increase blood pressure in some patients. Arava is contraindicated to patients with severe immunodeficiency states (e.g. AIDS), impairment of liver function, severe hypoproteinemia (e.g. in nephrotic syndrome), significantly impaired bone marrow function.
Coadministration of Arava with activated charcoal may lead to decrease in Arava efficacy. Live vaccines are not recommended to be administered in patients if they are taking Arava.The therapeutic efficacy of Arava can be affected by medications for asthma treatment (theophylline), muscle relaxant medicines (tizanidine), oral contraceptives, anti-inflammatory drugs (sulfasalazine, indometacin, ketoprofen), certain drugs for cancer treatment (daunorubicin, methotrexate).
Disclaimer
Review of immunomodulatory agent Arava is provided here solely for informational purposes. Information about Arava and antirheumatic therapy under no circumstances should be used instead of consultation with the immunologist or rheumatologist. In no event the online pharmacy shall not be liable for any loss or damage arising from the use or inability to use this review about Arava.
Arava side effects
Pyrimidine synthesis inhibitor Arava may cause some adverse reactions; usually they are expressed as nausea, leucopenia, weight loss, musculoskeletal disorder. Certain psychopathological disorders, expressed as asthenia, dizziness, headache, and gastrointestinal disturbances - diarrhea and dyspepsia can be observed as well.
Sometimes adverse reactions of Arava can be expressed as paraesthesia and skin disorders, such as mild allergic reactions or rash, and respiratory infections. In addition, hypertension and alopecia are rarely reported during the rheumatoid arthritis treatment with Arava pills.
Ventolin is a medicament for eliminating asthma attacks (bronchial) and other reversible diseases with bronchial obstruction.
The main active substance is salbutamol.
Endep - tricyclic antidepressant. The mechanism of antidepressive action is connected with increase in concentration of noradrenaline in synapses and/or serotonin in CNS (decrease in return absorption). Accumulation of these neurotransmitters results from inhibition of their return capture by membranes of presynaptic neurons.
Actos, which is pioglitazone - is prescribed to patients with diabetes of type 2 (both as monotherapy, and in a form of the combined therapy with sulphonylurea, metformin or insulin as additional medicine to dietotherapy and physical exercises). Pioglitazone represents peroral hypoglycemic medicine of Thiazolidinediones alignment which effect depends on insulin presence. It is a high-selective agonist of gamma receptors, activated by proliferator of peroxysom (PPAR-γ).
Augmentin - the Antibiotic of a broad spectrum of activity. It has bacterolytic (destroying bacteria) effect. It is active concerning a wide range of aerobic and anaerobic gram-positive and aerobic gramnegative microorganisms, including strains producing betalactamase. It is prescribed at diagnosing of bacterial infections caused by microorganisms, sensitive to drug: infections of upper respiratory tracts, bacterial infections of skin and soft tissues, infections of urogenital tract, sepsis, infection pelvic organs.
Ciplox is a medicine which is antimicrobial of the fluoroquinolone group. The system of action is connected with exposure to DNA bacteria. The medicine eliminates microorganisms that are both at rest and reproduction. A range of action of the drug includes such types of negative and positive microorganisms: Shigella, Salmonella, Citrobacter, Klebsiella, Enterobacter, Serratia, Hafnia, Edwardsiella and others. It is resistant to Ureaplasma uralyticum, Nocardia asteroids, Treponema pallidum. Such defiance to the drug develops slowly and gradually.
Floxin - antimicrobic broad-spectrum agent from group of fluroquinolone. It is active concerning the microorganisms producing beta lactamelements and fast-growing atypical mycobacteria. It is taken at respiratory infection, the ENT organs, skin, soft tissues, bones, joints, abdominal cavity, urinary tract.
Flagyl - antiprotozoan and antimicrobic drug. It is prescribed at treatment of protozoan inspections (abenteric amebiasis, including amoebic abscess of liver, an intestinal amebiasis, trichomoniasis, giardiasis, balanthidiasis, lambliasis, skin leushmaniosis, mecotic vaginitis, mecotic urethritis), pseudomembranous colitis, gastritises, ulcer, prevention of postoperative complications (especially interventions at segmented intestine, perirectal area, appendectomy, gynecologic operations).
Stromectol - a medical preparation that effectively cope with many kinds of parasites. It is used to treat lice, scabies, as well as onchocerciasis (river blindness) and other nematodes in humans and animals. It is applied externally and internally, depending on the disease.
Avalide is an effective medicine which aim is to lower the blood pressure. Hypertension provokes serious diseases as strokes, heart attack, and problems with the kidney. An angiotensin receptor blocker and diuretic are the basic components of the drug. The first one relaxes the walls of the blood vessels letting the blood move freely without the pressure. The second component stimulates urination so that a patient can get rid of extra salt and water which also provoke high blood pressure.
Exforge the combined antihypertensive which includes amlodipine and valastran. Valsartan - a specific blocker of AT1 receptors of angiotensin II. Amlodipin - calcium channel blocking agents of III generation, inhibits transmembrane receipt of Ca2+ in cardiomyocytes and smooth muscle cells of vessels, by weakening them.
Caverta - another affordable version of Indian Viagra created by Ranbaxy, released as Caverta 100mg and Caverta 50mg.
A symptomatic medication against vomiting and nausea of various origins. Used at vomiting caused by radiation therapy or cytotoxic drugs intake, hypotony and atony of the stomach and intestines, biliary dyskinesia, reflux esophagitis, flatulence, aggravation of gastric ulcer and duodenal gut, when performing contrast studies of the gastrointestinal tract. It reduces the moving activity of the esophagus, increases the tone of the lower esophageal sphincter, accelerates gastric emptying, and accelerates the movement of food through the small intestine without causing diarrhea. Stimulates the secretion of prolactin.
Levaquin is used to treat infections of the lower respiratory tract, urinary tract, kidneys, skin, soft tissues, chronic bronchitis, acute sinusitis, chronic bacterial prostatitis and tuberculosis. The drug is a fluoroquinolone, a broad-spectrum antimicrobial bactericide. It blocks DNA gyrase and topoisomerase IV, disrupts supercoiling and cross-linking of DNA gaps, suppresses DNA synthesis, causes profound morphological changes in the cytoplasm, cell wall and bacterial membranes.
An antiarrhythmic Ia class drug, a blocker of the "fast" Na+ channels. It has a membrane stabilizing, anti-arrhythmic, hypotensive and m-anticholinergic action. In normally functioning sinus node it causes acceleration of the sinus rhythm due to the antimuscarinic effect.
The drug dilates coronary vessels (mostly arterioles) and causes a significant increase in volumetric blood flow velocity. Increases the content of oxygen in venous blood of coronary sinus and its absorption by myocardium. Promotes the development of collateral coronary circulation, reduction in a systemic vascular resistance, improves microcirculation, has angioprotective action.
Strattera - the drug with an international non-proprietary name of the active substance - Atomoxetine, it is intended as a sympathomimetic agent for the prevention and treatment of attention deficit hyperactivity disorder (ADHD) in children 6 years of age and older, adolescents and adults.
Zerit - treatment of infection caused by HIV, with severe clinical manifestations and ineffectiveness or intolerance of zidovudine, and other antiretroviral drugs. The nucleoside analogue of thymidine is phosphorylated by cellular enzymes to its active form - stavudine triphosphate. Suppresses reverse transcriptase of HIV, cellular DNA polymerases (beta and gamma), inhibits the synthesis of viral and mitochondrial DNA. It is active against HIV-1.
Flexeril - medicine acting against muscular spasms. It possesses sedative action, it is not recommended to be engaged in potentially dangerous types of activity if a person takes Flexeril. As well as in a case with narcotic analgetics, Flexeril is not recommended to take longer than seven days as in case of a long taking there can be a dependence.
Actonel, which is risedronate - is prescribed for treatment and prevention of osteoporosis (post-menopausal, caused by corticosteroids), Paget disease. Risedronate binds to substance of a bone tissue, inhibits its resorption mediated by osteoclasts and reduces a bone turn (does not break process of formation of a bone). It increases the biomechanical strength and volume of bone mass. The maximum decrease in a bone turn is observed in 3-6 months, remaining at the same level during a course of treatment.
Synthroid finds use as a hormone-regulating agent for managing low levels of triiodothyronine/thyroxine. It also has a pronounced therapeutic effect on goiters of certain types. Synthroid often accompanies surgeries and other medical means of treating thyroid cancer. The drug compensates for the insufficient production of thyroid hormones by standing in their place as a synthetic substitution. Compensations of this kind help the patient’s body to restitute the normal rate of metabolism. Synthroid also helps to fight obesity due to its ability to remove the initial thyroid gland-related causes as such.
Anti-migraine drug. Specific and selective agonist of 5-HT1-serotonin receptors, localized predominantly in the blood vessels of the brain and it does not affect other subtypes of 5-HT-serotonin receptors (5-HT2-7). Causes narrowing of the vessels of the carotid arterial bed, that supply extracranial and intracranial tissues with blood (vasodilation of the meninges and / or their edema is the main mechanism of migraine development in humans) without significantly affecting cerebral blood flow.
An anti-migraine drug. Used for emergency treatment to eliminate migraine, with aura as well. A selective agonist of 5-hydroxytryptamine 1D receptors. The effect can be observed within 30 minutes after the intake.
Rizact -pills swallowed for the urgent care of the headache phase within the attacks of migraines. This Cipla product is a great painkillerthanks to an action of Rizatriptan, which is characterized by an analgesic effect.
The drug is used for treatment of infectious diseases such as community acquired pneumonia, exacerbation of chronic bronchitis, acute sinusitis, pharyngitis and skin infections. The active ingredient in Omnicef is cefdinir—a semi-synthetic cephalosporin broad-spectrum antibiotic of the third generation for oral administration. Like other cephalosporin antibiotics, cefdinir has a bactericidal action against susceptible organisms through the inhibition of synthesis of bacteria peptidoglycan cell walls by interfering with the final stage of transamination, required for cross-linking.
Dapsone antibacterial agent, which is active concerning Mycobacterium leprae and tuberculosis. It has bacteriostatic action similar to antagonists of p-aminobenzoic acid.
The effect of clomipramine is to inhibit the opposite neurological catching of serotonin and noradrenaline. The most crucial is the suppression of serotonin recapture. In addition, the medicine has a broad range of other pharmacological actions: alpha 1-adrenoliticheskoe, anticholinergic, antigestagen and antiserotonergic. The pill acts on the depressive disorder in general. The difference is usually observed after 2-3 weeks of therapy. Acticine also has a specific influence on obsessive-compulsive disorders.
Differin is a white gel or cream. The drug is used to treat acne. It can also be used to combat comedones. Differin monotherapy is helpful in case of minor acne. For the treatment of severe and moderate degree of acne, the drug is used in conjunction with systemic drugs (antiandrogens, antibacterial agents). The drug is well tolerated. It rarely causes irritation, so its use is good even for those who have sensitive skin with acne. The gel is more suitable for oily skin and the cream suits better for dry skin.