Promethazine reduces the permeability of capillaries, swelling of the mucous membranes, itching. Has adrenolytic, moderate peripheral and central cholinolytic action. Inhibits histamine-N-methyltransferase, blocks central histamine H3 receptors. Oppresses the central nervous system, has a sedative, anxiolytic, antipsychotic and hypnotic effect, lowers body temperature. Reduces the excitability of the vestibular receptors, eliminates dizziness. Has antiemetic effect.
Promethazine
| Package | pill | Total price | Save | Order |
|---|---|---|---|---|
| 25mg × 60 Pills | $0.50 | $29.86 + Bonus - 4 Pills | - | Add to cart |
| 25mg × 90 Pills | $0.47 | $42.11 + Bonus - 7 Pills | $2.70 | Add to cart |
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Product Description
Promethazine - causes sedative effect, has antiemetic effect. It has also pronounced to be an adrenoblocking remedy, which moderates peripheral and central anticholinergic action. The effect starts already in 20 minutes after ingestion and lasts up to 6 hours, sometimes up to 12 hours.
The drug is used to cure some allergic diseases and reactions such as: rash, itching, eczema, drug rash, serum sickness, Quincke's edema, hay fever, anaphylactic shock, bronchial obstructive syndrome (as part of complex therapy).
Also it is prescribed for the treatment of skin diseases (including eczema, neurodermatitis, diathesis, contact dermatitis and toxicodermia).
Safety information
When administered orally for adults, the daily dose of the drug is 75-100 mg.
Maximum dosage: during oral administration, single dose - 75 mg, daily - 500 mg; It is used in the composition of lytic mixtures.
Children of 1 - 2 years take 5-10 mg 1-2 times a day; from 2 - 5 years - 5-10 mg 1-3 times a day; From 5 - 10 years - 5-15 mg 1-3 times a day; Older than 10 years and adolescents take 5-20 mg of Promethazine 1-3 times a day. In case of emergency (asthmatic status, false cereal), the dose may be increased to 1-2 mg / kg.
Contraindications:
- simultaneous use of MAO inhibitors,
- coma (including on the background of alcohol intoxication),
- severe disorders of the liver function,
- first trimester of pregnancy,
- lactation (breastfeeding),
- early childhood (2 months),
- hypersensitivity to promethazine or other phenothiazine derivatives.
Side effects
- Moderately expressed numbness of the oral mucosa, dry mouth, nausea, constipation, diarrhea, unpleasant sensations; Rarely - jaundice.
- Drowsiness, dizziness, anxiety, lethargy, fatigue, impaired coordination of movements, impaired vision; Rarely - tinnitus, euphoria, nervousness, insomnia, seizures, oculogic crisis, catatonic status, hysteria, psychomotor agitation, extrapyramidal disorders, headache, nystagmus.
- Tachycardia, bradycardia, palpitation, fainting, arterial hypotension (with iv introduction), arrhythmias.
- Contact dermatitis, photosensitivity, urticaria.
- Leukopenia, agranulocytosis, aplastic anemia, thrombocytopenic purpura.
- Exanthema, urticaria, angioedema, anaphylactic reactions.
- Irregular breathing, urinary retention.
A lipid-lowering agent. Reversibly inhibits HMG-COA reductase, inhibits the cholesterol synthesis at the stage of mevinolinic acid and moderately reduces its intracellular concentration. The indications for the drug use include: primary hypercholesterolemia mainly of IIa and IIb types, under the ineffective diet treatment in patients with increased risk of coronary atherosclerosis, hypercholesterolemia combined with hypertriglyceridemia; prevention of coronary artery disease. The drug decreases the risk of myocardial infarction, the need for revascularization of the myocardium, deaths from cardiovascular system diseases.
Nootropil improves cognitive processes, memory, attention, and mental performance.
Nootropilum affects the CNS, by changing the speed of propagation of the excitation in the brain, improves metabolic processes in nerve cells, improves by acting on the rheological characteristics of blood and causing no vasodilatory action.
Betapace - beta adrenoblocker, antiarrhytmic medicine. It is taken for treatment of ventricular arrhythmia, tachycardia, supraventricular arrhythmia, tachycardia at thyrotoxicosis, angina of effort, especially at combination with tachyarrhythmias, arterial hypertension, hypertrophic cardiomyopathy, prolapse of the mitral valve, prevention and treatment of myocardial infarction at stable condition of the patient.
Haldol antipsychotic remedy, butyrophenone derivative. It has a powerful antipsychotic effect, moderate sedation. The mechanism of antipsychotic action of haloperidol is associated with the blockade of dopamine receptors in the mesocortex and limbic system.
Xalatan is a chemical analog of the hormone prostaglandin. It is a topical agent available in the form of eye drops with a concentration of latanoprost 50 mcg/ml. Its mode of action is similar to the one of its natural equivalent – the drug increases the flow of intraocular fluid from the hypertensive eyeball. As a result, the pressure in the eyeball slowly decreases. Since this symptom frequently accompanies various eye diseases, Xalatan is often prescribed in combination with other medicines. Today, this drug is among the high-priority agents in the treatment of such an ubiquitous disease as glaucoma.